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,
June 2019 in “Clinical research in dermatology” Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
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,
August 2021 in “International journal of molecular sciences” PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.
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,
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,
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,
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,
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,
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263 citations
,
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248 citations
,
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227 citations
,
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114 citations
,
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114 citations
,
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96 citations
,
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91 citations
,
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81 citations
,
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79 citations
,
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51 citations
,
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,
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,
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46 citations
,
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,
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,
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,
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,
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,
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,
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,
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24 citations
,
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,
September 2021 in “Frontiers in Cellular and Infection Microbiology” Testosterone's effects on COVID-19 are unclear and need more research.