research Author response: Coordinated hedgehog signaling induces new hair follicles in adult skin
Hedgehog signaling can create new hair follicles in adult skin but may increase cancer risk.
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900-930 / 1000+ resultsresearch Faculty Opinions recommendation of Nonviral in situ green fluorescent protein labeling and culture of primary, adult human hair follicle epithelial progenitor cells.
Researchers developed a method to label and study human hair follicle stem cells using a fluorescent protein.
research Enrichment and characterization of human dermal stem/progenitor cells using collagen type IV
Scientists identified a group of human skin cells with high growth and regeneration potential.
research Progenitor cells expressing nestin, a neural crest stem cell marker, differentiate into outer root sheath keratinocytes
Nestin-expressing progenitor cells become outer root sheath keratinocytes.
research Mutation of the doublecortin gene in male patients with double cortex syndrome: Somatic mosaicism detected by hair root analysis
Hair root analysis can effectively detect somatic mosaicism in double cortex syndrome.
research Epithelial skirt and bulge of human facial vellus hair follicles and and associated Merkel cell-nerve complex
Merkel cells are abundant in facial vellus hair follicles, especially during the anagen phase.
research Analyse de la régulation du gène Hairless et identification des voies de signalisation affectées chez les mutants «bald Mill Hill».
The mutant HR bmh protein affects hair follicle formation by failing to repress vitamin D receptor activity.
research Differential expression levels of Sox9 in early neocortical radial glial cells regulate the decision between stem cell maintenance and differentiation
Sox9 levels in brain stem cells affect whether they stay as stem cells or become neurons.
research 545 Skin Organoids derived from NCSTN mutated patient-induced pluripotent stem cells recapitulate Hidradenitis Suppurativa pathogenic hallmarks
Skin organoids with NCSTN mutation show changes in hair follicle development and higher inflammation, key features of Hidradenitis Suppurativa.
research 1390 Active hair growth is fuelled by conveyor-belt like differentiation of germinative layer cells
Hair growth is driven by cells that move and change like a conveyor belt.
research Mapping Human Skin: One Sequenced Cell at a Time
The article concludes that creating a detailed map of normal human skin at the single-cell level is important.
research Colourless side of the nude mutation: Foxn1 and hair pigmentation
Foxn1 is essential for hair pigmentation by directing pigment transfer to hair cells.
research Dermal‐Epidermal Cross‐Talk: Differential Interactions With Microvascular Endothelial Cells
Human dermal fibroblasts help microvascular endothelial cells grow, but not vice versa.
research Optimization of hair follicle spheroids for hair-on-a-chip
The method could grow hair in lab settings without using animals.
research 685 Modelling intrinsic and extrinsic cellular senescence in vitro with complex bioengineered human skin constructs
Bioengineered skin models aging well, useful for studying aging and testing treatments.
research 1410 Single-cell RNA sequencing reveals POUF51 and HES3 as regulators of the stem cell population in psoriasis
POUF51 and HES3 are key in controlling stem cell numbers in psoriasis.
research Human follicular stem cells: their presence in plucked hair and follicular cell culture
Stem cells are present in plucked hair follicles and can be maintained in culture.
research Stem Cells in the Body
Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.
research Multifunctional Merkel cells: Their roles in electromagnetic reception, finger-print formation, Reiki, epigenetic inheritance and hair form
Merkel cells may have roles in sensing magnetic fields, creating fingerprints, Reiki energy healing, passing on environmental information to offspring, and influencing hair shape.
research Classic versus non‐classic: A survival Kit for life in the skin
Melanocytes in different body areas have evolved to perform specific functions based on their location.
research There and Back Again: Hair Follicle Stem Cell Dynamics
Hair follicle stem cells can return to their original niche and help regenerate hair.
research Hair follicle stem cell fate supports distinct clinical endotypes in hidradenitis suppurativa
Different types of hidradenitis suppurativa need specific treatments based on unique skin cell issues.
research Decision letter: Hair follicle epidermal stem cells define a niche for tactile sensation
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
research Receptor types in cat hairy skin supplied by myelinated fibers.
Cats' hairy skin has different touch receptors connected by myelinated fibers.
research Ptch2 is a Potential Regulator of Mesenchymal Stem Cells
Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.
research 773 Generation of human hair follicle organoids in vitro and ex vivo by co-culture of primary human hair matrix keratinocytes and dermal papilla fibroblasts
Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.
research Canine Follicle Stem Cell Candidates Reside in the Bulge and Share Characteristic Features with Human Bulge Cells
Canine hair follicles have stem cells similar to human hair follicles, useful for studying hair disorders.
research Novel mutation in PTCH1 gene in a patient with basal cell nevus syndrome and uterus bicornis
research Genome-wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage
Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.
research Three-row stereocilia model predicts mammalian hair bundle behavior
The model explains how mammal ear hair cells respond to sound and adapt.