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Sexual Dysfunction in Subjects Treated with Inhibitors of 5α-Reductase for Benign Prostatic Hyperplasia: A Comprehensive Review and Meta-Analysis

research Sexual dysfunction in subjects treated with inhibitors of 5α-reductase for benign prostatic hyperplasia: a comprehensive review and meta-analysis

66 citations , April 2017 in “International Journal of Andrology”

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

research The utility of DHL-HisZnNa, a novel antioxidant, against anticancer agent-induced alopecia in breast cancer patients: a multicenter phase II clinical trial

4 citations , February 2019 in “Breast Cancer Research and Treatment”

DHL-HisZnNa may help reduce hair loss from chemotherapy, but more research is needed.

research Evaluating the safety profile of α-1 blockers, 5α-reductase inhibitors, and PDE5I for BPH: a disproportionality analysis of real-world adverse events based on FDA adverse event reporting system (FAERS)

March 2026 in “Figshare”

These medications for BPH have known risks and may have new side effects.

research Dihydroartemisinin loaded nanostructured lipid carriers (DHA-NLC): evaluation of pharmacokinetics and tissue distribution after intravenous administration to rats.

11 citations , September 2010 in “PubMed”

DHA-NLC may improve drug delivery and reduce side effects for cancer treatment.

research Abstract 153: Inhibition of the 5-a-reductase Reduces Cardiac Hypertrophy and Improves Cardiac Function

August 2013 in “Circulation Research”

Finasteride reduces heart enlargement and improves heart function.

research Cardiovascular Toxicities of Androgen Deprivation Therapy

45 citations , April 2021 in “Current Treatment Options in Oncology”

ADT for prostate cancer may harm the heart, but GnRH antagonists might be safer.

research Release systems based on self-assembling RADA16-I hydrogels with a signal sequence which improves wound healing processes

1 citations , April 2023 in “Scientific Reports”

Self-assembling RADA16-I hydrogels with bioactive peptides significantly improve wound healing.

research Drugs that affect autonomic functions or the extrapyramidal system

January 2009 in “Side effects of drugs annual”

Some drugs can cause serious side effects like heart issues and nervous system problems, but certain drugs for Parkinson's and overactive bladder may be safer, though they still have some common side effects.

research Ophthalmohypertension caused by minoxidil

May 2025 in “Modern technologies in ophtalmology”

Minoxidil might rarely increase eye pressure.

Finasteride and Tamsulosin: Sexual Side Effects in a 61-Year-Old Man with Benign Prostatic Hyperplasia

research Finasteride/tamsulosin

December 2019 in “Reactions Weekly”

Man stopped medications due to sexual side effects, found relief with prostatic artery embolisation.

research The effects of topical diazoxide on hair follicular growth and physiology of the stumptailed macaque

11 citations , May 1990 in “Journal of Dermatological Science”

Diazoxide applied to the skin can increase hair growth without harmful side effects.

research Dutasteride: a guide to its use as monotherapy in benign prostatic hyperplasia

June 2008 in “Drugs & therapy perspectives”

Dutasteride effectively treats benign prostatic hyperplasia, improving symptoms and quality of life.

research Controlled Release of Minoxidil through Hydrogel Cross-Linking to Treat Androgenetic Alopecia

June 2025 in “ACS Biomaterials Science & Engineering”

A new method using hydrogels and microneedle patches improves minoxidil delivery for better hair growth.

research Biochemical Mechanisms by Which Minoxidil Sulfate Influences Mammalian Cells

13 citations , January 1987 in “Dermatology”

Minoxidil sulfate relaxes blood vessels by increasing potassium permeability.

research Application of histamine receptors H2R, H3R and H4R, but not H1R, in dermatology

September 2014 in “International Journal of Dermatology and Venereology”

Certain histamine receptors (H2R, H3R, H4R) have unique roles in treating skin diseases, with H2R helping with chronic urticaria and other conditions, H3R providing pain relief and allergy benefits, and H4R reducing inflammation and itchiness.

research Risperidone

October 2011 in “Reactions Weekly”

A man had a severe allergic reaction to sulfasalazine, with symptoms improving after treatment and follow-up.

research 595 In vitro evaluation of skin distribution and human dermal papilla cells proliferation for minoxidil 5% topical lotion hydrogel

July 2022 in “Journal of Investigative Dermatology”

The new minoxidil hydrogel is a promising alternative for hair loss treatment, with similar effectiveness and less skin irritation.

research Spironolactone

February 2024 in “Practical Diabetes”

Spironolactone helps reduce hospital visits and death from heart issues, lowers blood pressure, but has unclear effects on heart failure with normal heart pump function and can cause high potassium and breast enlargement in men.