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Certain blood metabolites are linked to female pattern hair loss, with some increasing risk and others offering protection.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Metabolite 7 is a strong inhibitor for Alzheimer's disease management.

Consider rare forms of CAH for accurate diagnosis and treatment.

Cholesterol helps hair grow by activating nerves and boosting hair follicle stem cells.

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.

The research found that measuring androgens in urine can give extra information about body metabolism and is linked to androgen levels in the blood, especially in young girls.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.

Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.

New vitamin D3 forms need the vitamin D receptor to reduce fibrosis in human cells.

The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.

Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

High doses of tryptophan may cause eosinophilic fasciitis.

Rodent models of PCOS show some hormone changes similar to humans, but also have key differences.

Higher BPA levels may be linked to idiopathic hyperandrogenemia in women.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Different types of skin on mice have unique chemical profiles related to how they grow and react to stress.

Mitotane changes steroid breakdown, affecting cortisol availability.

5α-reduced progestogens may reduce mood issues and brain damage linked to HIV-1 Tat.

Alopecia in these mice is caused by defective hair cycle communication due to missing vitamin D receptor function, not vitamin D levels.

Vitamin A is important for healthy skin and hair, influencing hair growth and skin healing, but UV light reduces its levels.