October 2017 in “The American Journal of Gastroenterology” Early diagnosis and nutritional support are crucial for managing Cronkhite-Canada Syndrome.
25 citations
,
June 2017 in “Journal of Investigative Dermatology” HPV8 causes skin cancer by expanding specific skin stem cells.
1 citations
,
February 1991 in “Journal of Biological Chemistry” 149 citations
,
July 2000 in “Molecular and Cellular Biology” Keratin 6a is important for quick wound healing from hair follicles.
November 2019 in “Harper's Textbook of Pediatric Dermatology” Mutations in keratin genes cause skin, hair, and nail disorders, with future treatments possible.
April 2009 in “The FASEB Journal” Keratin biomaterials from human hair help nerve regeneration by activating Schwann cells.
10 citations
,
January 2010 in “International journal of trichology” Keratin-associated proteins are part of the developing hair fiber cuticle.
36 citations
,
December 2004 in “British Journal of Dermatology” The cyst had unusual keratin spherules and resembled bone marrow.
November 2020 in “Research Square (Research Square)” Keratin injections in mice can stimulate hair growth and might help treat hair loss.
26 citations
,
October 1998 in “Experimental Dermatology” A keratin hHb6 mutation causes a hair disorder with varying severity, influenced by other factors.
31 citations
,
January 2004 in “Methods in cell biology” Hair and follicle keratins differ in structure and expression, especially in cysteine content.
8 citations
,
March 2019 in “Journal of Biomedical Materials Research Part A” Sulfated hyaluronan in collagen helps hair follicle cells grow and develop better for skin grafts.
January 2024 in “The Indian Veterinary Journal” A young goat with skin issues improved with medication and supplements.
2 citations
,
November 2006 in “Pump Industry Analyst” Pilomatricomas don't follow the usual hair follicle cell differentiation process.
48 citations
,
May 1991 in “The journal of investigative dermatology/Journal of investigative dermatology” Trichohyalin is also found in the outer layers of normal human skin.
7 citations
,
October 2024 in “Cells” Autophagy is essential for proper skin cell development and function.
55 citations
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December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” Keratinocytes control how melanocytes work.
87 citations
,
September 2012 in “Journal of Cell Science” Keratins are crucial for tissue strength, and mutations in keratin genes can lead to various diseases, highlighting the need for targeted therapies.
January 2022 in “The Pan African medical journal” Hypertrichosis causes excessive hair growth and needs psychological support due to its impact on self-esteem.
8 citations
,
August 1993 in “Colloid & Polymer Science” The observed "toughening" in keratin was actually due to water evaporation, not a real change in keratin.
40 citations
,
September 2010 in “Journal of Biological Chemistry” Keratin K80 is an ancient protein found in various tissues, important for cell structure and tissue differentiation.
2 citations
,
August 2013 in “Journal of Investigative Dermatology” Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.
26 citations
,
May 2014 in “BioEssays” Using neurohormones to control keratin can lead to new skin disease treatments.
40 citations
,
November 2021 in “International Journal of Molecular Sciences” Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.
41 citations
,
May 2012 in “Advanced Healthcare Materials” Human hair keratins improve cell adhesion and growth on culture surfaces.
7 citations
,
April 2004 in “International Journal of Dermatology” The newborn's skin blistering is due to a genetic condition called epidermolytic hyperkeratosis.
July 2007 in “Manuals in biomedical research”
16 citations
,
August 2019 in “Cell Proliferation” Keratinocytes help keep hair follicle cells and skin cells separate in 3D cultures, which is important for hair growth research.
Keratinocytes grew and migrated into hair follicle areas but disappeared after 15-20 days.