September 2019 in “Journal of Investigative Dermatology” Scientists used stem cells to create a model of the skin disease Epidermolysis Bullosa simplex, which helped them understand its molecular mechanisms and could aid in finding treatments.
5 citations
,
April 2014 in “International Journal of Pediatric Endocrinology” Prepubertal girls with hypertrichosis have more sensitive androgen receptors, leading to increased body hair growth.
15 citations
,
January 1988 Hair follicles have unique proteins that vary by species and are influenced by nutrition.
27 citations
,
November 1991 in “Journal of Investigative Dermatology” 686 citations
,
February 2002 in “Current Opinion in Cell Biology” Keratin filaments are crucial for cell structure and protection, with ongoing discoveries about their genes and functions.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.
Daily hair care may cause holes in hair fibers.
26 citations
,
December 2019 in “Stem Cell Reports” Proper tissue repair in adult skin requires specific histone hypomethylation.
45 citations
,
October 2019 in “Clinical and Experimental Dermatology” Targeted therapies promoting differentiation could help treat basal cell carcinoma by exhausting cancer stem cells.
August 2015 in “PubMed Central” Epithelial-derived Pop-Up Keratinocytes (ePUKs) may enhance wound healing in regenerative medicine.
August 2024 in “Postgraduate Medical Journal” A rare skin reaction from cancer treatment was successfully managed with topical treatments and antihistamines.
44 citations
,
October 1990 in “Archives of Dermatological Research” The connective tissue around hair follicles changes structure throughout the hair cycle.
26 citations
,
January 1964 in “Experimental Cell Research” January 2020 in “프로그램북(구 초록집)” The skin has two main layers, the epidermis and dermis, which work together and are essential for diagnosing skin conditions.
January 2005 in “Enlighten: Publications (The University of Glasgow)” Melanocyte pathology requires keratinocyte hyperplasia and regulation dysfunction.
1 citations
,
January 2016 in “Frontiers in Bioengineering and Biotechnology” Human hair keratin is a promising and sustainable biomaterial for tissue regeneration.
42 citations
,
July 2015 in “PLoS ONE” The study revealed the detailed structure of a keratin dimer, aiding understanding of how intermediate filament proteins function.
6 citations
,
November 2001 in “Der Hautarzt” Photothermolysis is the best method for permanent hair removal.
11 citations
,
January 2010 in “Current problems in dermatology” Ichthyoses are genetic skin disorders that affect the skin's barrier function.
36 citations
,
January 1994 in “Cell and Tissue Research” 32 citations
,
December 1963 in “Pharmacological Reviews” Some drugs can cause hair loss and skin issues.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Ezh2 controls skin development by balancing signals for dermal and epidermal growth.
11 citations
,
September 1996 in “Journal of applied polymer science” Potassium cyanide treatment changes hair's disulfide bonds, making it more elastic.
26 citations
,
August 2014 in “Veterinary Dermatology” Sphynx cats have abnormal hair follicles and keratinization affecting their skin.
85 citations
,
September 2013 in “International Journal of Molecular Sciences” Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.
53 citations
,
July 2011 in “Biomaterials” Human liver cells stick to hair protein materials mainly through the liver's asialoglycoprotein receptor.
September 1998 in “Journal of the European Academy of Dermatology and Venereology” Different racial groups have varying keratin proteins, affecting hair texture and strength.
21 citations
,
June 2004 in “Experimental Dermatology” Ber‐EP4 marks cells related to the secondary hair germ in hair follicles.
27 citations
,
July 1983 in “Journal of Investigative Dermatology” 15 citations
,
May 2014 in “Journal of Biological Chemistry” A chimeric keratin partially improved skin structure in mice lacking keratin 5, but didn't fully restore normal skin.