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Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.

Metabolic syndrome in kids and teens is linked to obesity and increases diabetes and heart disease risk; early lifestyle changes are crucial for management.

MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.

Taking thyroid medication reduced the patient's pituitary gland swelling and improved her symptoms.

Metformin can help diagnose and treat high testosterone levels in women, often due to insulin resistance rather than a tumor.

Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.

Biotin mega-dose therapy led to dramatic improvement in a newborn with a rare metabolic disorder.

Metformin improved insulin resistance and BMI in overweight Taiwanese women with PCOS, and a 2-hour insulin test may be a good screening tool.

Targeting lipid metabolism can help treat advanced, resistant cancers.

Certain skin conditions can indicate a higher risk of diabetes and heart problems.

The ketogenic diet can worsen biotin deficiency, suggesting a need for biotin supplements.

Women with PCOS, especially if they are obese, are more likely to have an underactive thyroid than women without PCOS.

Skin conditions can indicate underlying metabolic issues.

Doctors often diagnose Cushing's syndrome late, which worsens symptoms; earlier detection is needed.

Certain metabolites may help diagnose and predict polycystic ovary syndrome.

Measuring certain hormones can help predict metabolic risk in women with PCOS.

A rare case of Cushing's syndrome and pheochromocytoma requires careful re-evaluation to avoid complications.

Children with metabolic syndrome often have skin problems like dark patches, skin tags, stretch marks, infections, acne, and psoriasis, which are linked to obesity and insulin resistance.

Altered DHEA metabolism in hair follicles may be linked to hair loss in balding men.

Overweight women with PCOS are more likely to have excess male hormones.

Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.

An unhealthy lifestyle increases the risk of metabolic syndrome.

Some skin problems can be signs of diabetes or other metabolic diseases and recognizing them can help diagnose and treat these diseases early.

A man's health improved after treating his undiagnosed adrenal insufficiency, which caused fatigue and weight loss.

PCOS has three subtypes, with 11-oxygenated androgens increasing metabolic risk.

Older age, obesity, hirsutism, and having children increase metabolic risk in women with PCOS.

A man's adrenal insufficiency was caused by a pituitary tumor linked to kidney cancer.

Increasing isoleucine intake improved skin and health issues in an infant with maple syrup urine disease.