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GlossaryBenign Prostatic Hyperplasia

non-cancerous enlargement of the prostate gland common in older men

Benign Prostatic Hyperplasia (BPH), also known as an enlarged prostate, is a non-cancerous increase in the size of the prostate gland. This condition is common in older men and can lead to urinary symptoms such as difficulty starting urination, a weak urine stream, and frequent urination, especially at night. BPH occurs due to hormonal changes and can be managed with medications, lifestyle changes, or surgical procedures if necessary.

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research Influencia del tratamiento con alfa bloqueantes e inhibidores de la 5 alfa reductasa en los hallazgos morfológicos e inmunohistoquímicos de la hiperplasia benigna de próstata

January 2002 in “Dialnet (Universidad de la Rioja)”

Finasteride treatment makes the prostate look more like a healthy one.

research Association of Benign Prostatic Hyperplasia with Male Pattern Baldness

54 citations , May 1998 in “Urology”

Men with enlarged prostates often have more severe baldness.

research Ejaculations and Benign Prostatic Hyperplasia: An Impossible Compromise? A Comprehensive Review

34 citations , December 2021 in “Journal of Clinical Medicine”

Men with BPH should discuss potential sexual side effects with doctors before treatment, as some treatments can affect ejaculation.

Prevalence of Metabolic Syndrome and Its Components Among Men With and Without Clinical Benign Prostatic Hyperplasia: A Large, Cross-Sectional, UK Epidemiological Study

research Prevalence of metabolic syndrome and its components among men with and without clinical benign prostatic hyperplasia: a large, cross-sectional, UK epidemiological study

31 citations , September 2015 in “BJUI”

Men with benign prostatic hyperplasia are more likely to have metabolic syndrome than those without it.

research Dihydroartemisinin attenuates benign prostatic hyperplasia in rats by inhibiting prostatic epithelial cell proliferation

4 citations , August 2021 in “Annals of Translational Medicine”

Dihydroartemisinin helps reduce prostate enlargement in rats by stopping the growth of prostate cells.

research Phytotherapy in Benign Prostatic Hyperplasia

3 citations , January 2018 in “Elsevier eBooks”

Serenoa repens is a common and effective plant-based treatment for mild-to-moderate prostate enlargement symptoms.

Tamsulosin Treatment for Benign Prostatic Hyperplasia and Risk of Severe Hypotension in Men Aged 40-85 Years in the United States: Risk Window Analyses Using Between and Within Patient Methodology

research Tamsulosin treatment for benign prostatic hyperplasia and risk of severe hypotension in men aged 40-85 years in the United States: risk window analyses using between and within patient methodology

70 citations , November 2013 in “The BMJ”

Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.

research Ursolic acid reduces prostate size and dihydrotestosterone level in a rat model of benign prostatic hyperplasia

44 citations , January 2012 in “Food and chemical toxicology”

Ursolic acid can shrink the prostate and lower a hormone linked to prostate growth in rats.

research Dutasteride for the treatment of benign prostatic hyperplasia

24 citations , June 2013 in “Expert opinion on pharmacotherapy”

Dutasteride effectively treats benign prostatic hyperplasia but isn't approved for preventing prostate cancer.

Benign Prostatic Hyperplasia: A Disorder of Androgen Metabolism in Males

research Benign Prostatic Hyperplasia: A Disorder of Androgen Metabolism in the Male

23 citations , May 1984 in “Journal of the American Geriatrics Society”

Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.

research The prevention of benign prostatic hyperplasia (bph)

12 citations , December 2016 in “Medical Hypotheses”

A vaccine may prevent benign prostatic hyperplasia (BPH).

research The Risk of Venous Thromboembolism (VTE) in Men with Benign Prostatic Hyperplasia Treated with 5-Alpha Reductase Inhibitors (5ARIs).

6 citations , August 2021 in “Clinical Epidemiology”

Men using 5-alpha reductase inhibitors for prostate issues may have a slightly higher risk of blood clots.

research Re: Androgenetic Alopecia as an Early Marker of Benign Prostatic Hyperplasia

5 citations , September 2012 in “The Journal of Urology”

Early hair loss may indicate future prostate issues.

research Patterns of Care for Newly Diagnosed Benign Prostatic Hyperplasia in the United States

4 citations , February 2016 in “The Journal of urology/The journal of urology”

Most care for benign prostatic hyperplasia follows guidelines, but 5-α reductase inhibitors are often used incorrectly.

research Pharmacological Effects of the Lipidosterolic Extract from Kigelia africana Fruits in Experimental Benign Prostatic Hyperplasia Induced by Testosterone in Sprague Dawley Rats

3 citations , February 2023 in “Journal of Experimental Pharmacology”

Kigelia africana fruit extract can prevent and reverse prostate enlargement in rats.

research Effect of a Benign Prostatic Hyperplasia (BPH) Xenobiotic - Croton membranaceus Müll.Arg. Root Extract on CYP1A2, CYP3A4, CYP2D6, and GSTM1 Drug Metabolizing Enzymes in Rat Model

1 citations , August 2020

Croton membranaceus root extract can change how drugs are processed in the body.

research The Risk of Benign Prostatic Hyperplasia and Prostate Cancer With Long-Term, Low Dose Finasteride Use in Adult Men with Nonscarring Alopecia: A Propensity-Matched Observational Study

April 2026 in “Urology”

Long-term, low-dose finasteride may reduce the risk of benign prostatic hyperplasia and prostate cancer.

research Evaluation of residual symptoms and anxiety among patients on therapy for benign prostatic hyperplasia at a Nigerian tertiary healthcare facility

January 2026 in “Journal of Pharmacy & Bioresources”

Many patients with benign prostatic hyperplasia experience high anxiety and residual symptoms, needing better anxiety management.

research Referee report. For: Recent advances in treatment for Benign Prostatic Hyperplasia [version 1; referees: 2 approved]

January 2015 in “Faculty of 1000 Research Ltd”

BPH treatment improved with personalized medicine, new drugs, and less invasive surgeries.

research Dutasteride: a guide to its use as monotherapy in benign prostatic hyperplasia

June 2008 in “Drugs & therapy perspectives”

Dutasteride effectively treats benign prostatic hyperplasia, improving symptoms and quality of life.

research Effect of dutasteride on the detection of prostate cancer in men with benign prostatic hyperplasia.

November 2005 in “The Journal of Urology”

Dutasteride may lower the chance of finding prostate cancer in men with enlarged prostates.

research Asociación entre disfunción eréctil y funcionalidad del subsistema conyugal en pacientes con hiperplasia prostática benigna

1 citations , August 2020 in “REMUS - Revista Estudiantil de Medicina de la Universidad de Sonora”

Erectile dysfunction is linked to marital issues in patients with benign prostatic hyperplasia.

research Acción de Finasteride sobre el volumen prostático en caninos con hiperplasia prostática benigna

1 citations , January 2002 in “El Servicio de Difusión de la Creación Intelectual (National University of La Plata)”

Finasteride effectively reduces prostate size in dogs with benign prostatic hyperplasia at a low, safe dose.

research UTILIZAÇÃO DE FINASTERIDA NO TRATAMENTO DA HIPERPLASIA PROSTÁTICA BENIGNA – RELATO DE CASO

March 2023 in “Enciclopédia Biosfera”

Finasteride effectively treats BPH but requires continuous use to maintain benefits.

research La combinación de finasteride y doxazosina fue más efectiva que la monoterapia en la hiperplasia prostática benigna

September 2004 in “Evidencia actualizacion en la práctica ambulatoria”

Using finasteride and doxazosina together works better for treating benign prostatic hyperplasia than using just one.

Comparison of the Therapeutic Effect Between Ethanolic Extract of Physalis Peruviana Fruit, Finasteride, and Terazosine on Benign Prostatic Hyperplasia Induced in Rats

research Comparación del efecto terapéutico entre el extracto etanólico del fruto de Physalis peruviana, Finasteride y Terazosine en la hiperplasia prostática benigna inducida en ratas

January 2018 in “Repositorio de Tesis - UNMSM”

Physalis peruviana extract is more effective in treating benign prostatic hyperplasia in rats than finasteride and terazosine.

Androgenic Alopecia as a Predictive Factor for Benign Prostatic Hyperplasia

research Alopecia androgénica como factor predictor de hiperplasia benigna de próstata

January 2018 in “Universidad Privada Antenor Orrego”

Male pattern baldness may be an early sign of noncancerous prostate enlargement.

research PREVALENCIA DE APEGO AL TRATAMIENTO CON FINASTERIDA EN PACIENTES CON HIPERPLASIA BENIGNA DE PRÓSTATA DE UN SERVICIO DE UROLOGÍA DEL I.S.S.S.T.E.

December 2008

Adherence to finasteride treatment for prostate issues is generally low.

Three-Month Treatment With a Long-Acting Gonadotropin-Releasing Hormone Agonist of Patients With Benign Prostatic Hyperplasia: Effects on Tissue Androgen Concentration, 5α-Reductase Activity and Androgen Receptor Content

research Three-Month Treatment With a Long-Acting Gonadotropin-Releasing Hormone Agonist of Patients With Benign Prostatic Hyperplasia: Effects on Tissue Androgen Concentration, 5α-Reductase Activity and Androgen Receptor Content*

82 citations , February 1989 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

research Cinnamomi Cortex (Cinnamomum verum) Suppresses Testosterone-induced Benign Prostatic Hyperplasia by Regulating 5α-reductase

43 citations , August 2016 in “Scientific Reports”

Cinnamomi cortex may help treat prostate enlargement by reducing related proteins.