research Minoxidil Overdosage: A Case Report
A man who drank too much hair growth medication got very sick but got better after hospital treatment.
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research An Investigation of Keratin 15 Function by Small Interfering Ribonucleic Acid Technology
Keratin 15 affects cell behavior and characteristics in skin cells.
research Evaluación de la seguridad de minoxidil oral a dosis bajas en el tratamiento de la alopecia
Low-dose oral minoxidil is generally safe for treating hair loss, with mostly mild side effects.
research Encapsulación en ciclodextrinas de compuestos con actividad frente a la alopecia androgénica masculina.
Encapsulating hair loss drugs in cyclodextrins improves their solubility and reduces scalp irritation.
research Mechanisms of proton inhibition and sensitization of the cation channel TRPV3
Acid can block TRPV3 from outside the cell but boost its function from inside.
research Is neuronal inhibition or excitability controlled by Na+K+2CL– transporters?
NKCC1 transporters help control neuron excitability and inhibition.
research Feedback between PI4P signaling and ER-PM contact sites orchestrates polarized root hair growth
research Cutaneous TRPV4 Potentiates the Afferent Transmission of Electroacupuncture Stimulation
TRPV4 channels in the skin may enhance the effects of acupuncture.
research The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2
A special receptor in sensory nerve endings helps control how they respond to stretching.
research 2‐Deoxy‐d‐glucose enhances tonic inhibition through the neurosteroid‐mediated activation of extrasynaptic GABAA receptors
2-DG reduces seizures by enhancing brain inhibition through specific receptor activation.
research 738 Cryo-EM and molecular dynamics of TRPV3 channel in activated state reveal structural features implicated in severe itch and hyperkeratosis
The TRPV3 channel structure changes linked to severe itch and hyperkeratosis were identified using cryo-EM.
research Potassium channel conductance as a control mechanism in hair follicles
research UV light may induce hypertrichosis through production of PGE2
UV light might cause excessive hair growth by increasing PGE2 in the skin.
research How Does pH Fit in with Oscillating Polar Growth?
pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.
research INTRODUCING THEORY LINKING GENESIS OF HAIR SHAFT BIPOLARITY WITH ARRECTOR PILI MUSCLE PROXIMAL ATTACHMENT
The document suggests that human hair has electrical charges because of a gap in nerve cell coverage that affects electromagnetic radiation.
research Potassium Channel Conductance as a Control Mechanism in Hair Follicles.
research Cytoplasmic Ca2+ concentrations in intact Merkel cells of an isolated, functioning rat sinus hair preparation
research Electroosmotic pore transport in human skin.
research Special collection on inward rectifying K+ channels
Inward rectifier potassium channels are important in many body functions and diseases, and could be potential drug targets.
research Author response: Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing
Reducing PIEZO1 speeds up wound healing.
research KCNQ Potassium Channels Modulate Sensitivity of Skin Down-hair (D-hair) Mechanoreceptors
KCNQ potassium channels help control the sensitivity of touch receptors in the skin.
research Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells.
Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.
research Novel modulatory effects of neurosteroids and benzodiazepines on excitatory and inhibitory neurons excitability: a multi-electrode array recording study
Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.
research The Emerging Structural Pharmacology of ATP-Sensitive Potassium Channels
KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.
research Dynamic Plasticity of Axons within a Cutaneous Milieu
Hair clipping can trigger axon growth and changes in the skin.
research 1372 Biological effects of electrical epilation on human hair follicles and perifollicular skin ex vivo
Electrical epilation damages hair follicles and surrounding skin, likely preventing hair regrowth.
research Plasticity of GABAergic Inhibition
Targeting specific GABA receptors may help treat epilepsy and postpartum depression.
research INTRODUCING GAP IN HAIR FOLLICLE ELECTROMAGNETISM AS MECHANISM FOR THE PRESENCE OF BIPOLAR ELECTRICAL CHARGES INHERENT IN THE HUMAN HAIR SHAFT
Human hair has bipolar electrical charges because of a gap in the hair follicle's electromagnetic field.
research Increased PHGDH expression uncouples hair follicle cycle progression and promotes inappropriate melanin accumulation
Increased PHGDH expression causes early melanin buildup in hair follicles.
research Modulating mechanosensory afferent excitability by an atypical mGluR
A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.