June 2021 in “Asian Journal of Medical Sciences” Vitamin B12 deficiency can cause reversible skin darkening.
August 2024 in “Journal of the Association of Physicians of India” Adding vitamin B12 to food like salt can effectively improve vitamin levels in rural areas.
11 citations
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August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which can be reversed with treatment.
July 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” Knuckle darkening can be an early sign of vitamin B12 deficiency.
77 citations
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August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which are reversible with treatment.
1 citations
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January 2013 in “Nasza Dermatologia Online” Vitamin B12 deficiency can cause reversible hair color loss in children.
4 citations
,
March 2020 in “JAAD Case Reports” Vitamin B12 deficiency can cause darkening of all nails.
16 citations
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February 2008 in “PubMed” Vitamin B12 deficiency can cause skin darkening and white hair, but it's reversible.
April 2024 in “International Journal of Advanced Research” Vitamin B12 deficiency is linked to hair loss and skin pigmentation changes.
9 citations
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September 2019 in “Journal of clinical sleep medicine” Vitamin B12 deficiency can rarely cause excessive daytime sleepiness.
2 citations
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October 2016 in “Nutrition in clinical practice” Vitamin B12 deficiency can cause facial dark spots that go away with treatment.
October 2007 in “European Neuropsychopharmacology”
January 2025 in “The International Journal of Gastroenterology and Hepatology Diseases” Vitamin B12 is crucial for hair and nerve health, and its malabsorption can cause hair loss and nerve damage.
August 2018 in “Journal of The American Academy of Dermatology” People with telogen effluvium and scalp discomfort might have low vitamin B12 and could benefit from B12 supplements.
4 citations
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January 2011 in “Journal of Cosmetics, Dermatological Sciences and Applications” Vitamin B12 may promote hair growth by affecting certain cell processes.
July 2022 in “Journal of Dermatology and Dermatologic Surgery” People with chronic hair loss often have lower Vitamin B12 levels.
20 citations
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July 1990 in “Clinical and experimental dermatology” Taking cyproterone acetate and ethinyl oestradiol for hair loss can lower vitamin B12 levels in women.
March 1993 in “Neuroscience letters” Biotin is important for metabolism, with specific daily intake recommendations, and deficiency can cause health problems.
August 2023 in “Natural Resources for Human Health” Vegetarians should take B vitamin supplements to avoid health issues.
November 2022 in “Gene Cell and Tissue” Zinc deficiency might affect vitamin B12 levels.
2 citations
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August 2024 in “Molecular Genetics & Genomic Medicine” Biotin mega-dose therapy led to dramatic improvement in a newborn with a rare metabolic disorder.
January 2019 in “Kocaeli tıp dergisi” People with chronic hair loss may have a higher chance of Vitamin B12 deficiency.
Taking too much biotin can mess up blood test results, which might lead to wrong diagnoses and treatments.
June 2024 in “British Journal of Dermatology” Vitamin B supplements may reverse grey hair.
October 2019 in “Turkderm” Patients with pernio have lower vitamin B12 and ferritin levels than healthy people.
8 citations
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January 2007 in “Hair transplant forum international” Vitamin B12 improves the health and growth of hair micrografts.
21 citations
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June 1991 in “Journal of Inherited Metabolic Disease” Selenium deficiency caused symptoms in a child, which improved with selenium supplements.
73 citations
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October 2001 in “Epilepsia” Children taking higher doses of valproic acid had lower biotinidase activity, which may lead to biotin deficiency, but biotin supplements could help.
1 citations
,
February 2022 in “Journal of the American Academy of Dermatology” Taking biotin supplements can be risky and often lacks evidence of effectiveness for skin, hair, and nail issues.
2 citations
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November 1995 in “American Journal of Obstetrics and Gynecology” Taking vitamin B6 corrected a pregnant woman's metabolic disorder, which changed her hair color.