75 citations
,
July 2013 in “The Journal of Clinical Endocrinology and Metabolism” Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.
30 citations
,
May 2015 in “Current Cardiology Reviews” Lower testosterone increases heart disease risk; higher estradiol increases risk in women.
November 2012 in “Experimental and Clinical Endocrinology & Diabetes” A new genetic mutation causes severe Leydig cell hypoplasia, affecting sexual development.
1 citations
,
January 2017 in “Journal of rare disease research & treatment” Obesity is common in PCOS patients and early treatment is important for their heart and metabolic health.
49 citations
,
April 1997 in “Human reproduction” Hormone therapy for excessive hair growth is as good with GnRHa as with high-dose CPA, but GnRHa has longer-lasting results.
August 2013 in “日本医療薬学会年会講演要旨集” Hair contains complex lipids, including cholesterol and fatty acids, similar to skin.
5 citations
,
May 2019 in “Hormone and Metabolic Research” Women with nonclassic 21-hydroxylase deficiency can have successful pregnancies through IVF, with certain factors affecting their chances.
February 2022 in “Mediators of Inflammation” Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.
1 citations
,
December 2016 in “Journal of Evolution of Medical and Dental Sciences” Hemodialysis patients often experience skin issues like dryness and itching, linked to certain blood chemical levels.
High insulin levels are more common and a better predictor of carbohydrate issues in women with PCOS than glucose tolerance tests.
September 2018 in “Dermatologic Therapy” Finasteride at 2.5mg/day may help postmenopausal women with hair loss.
January 2026 in “Open Veterinary Journal” PUFA-rich oil improves pet hair quality but may raise triglyceride levels.
4 citations
,
January 1994 in “Journal of hepatology” Cyclosporine A therapy changes sex hormone levels differently in pre-menopausal and post-menopausal women with primary biliary cirrhosis.
2 citations
,
August 2024 in “Molecular Genetics & Genomic Medicine” Biotin mega-dose therapy led to dramatic improvement in a newborn with a rare metabolic disorder.
September 2025 in “Value in Health” 10 citations
,
October 2019 in “Iranian Biomedical Journal” Simvastatin helps hair follicle stem cells turn into skin cells.
19 citations
,
August 1999 in “European journal of endocrinology” The study concluded that testing hormone levels after stimulation is not reliable for identifying carriers of 21-hydroxylase deficiency; genetic testing is necessary.
April 2011 in “Global journal of health science” Aldactone effectively reduces hair thickness in women with excessive hair growth, both alone and with other treatments.
1 citations
,
August 2024 in “Journal of Pharmacy & Pharmaceutical Sciences” The DPCP/HPβCD complex improves solubility and anti-inflammatory effects for alopecia areata treatment.
February 2022 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Low-dose oral minoxidil is a promising, safe treatment for various hair diseases, improving hair thickness and density, but more research is needed on long-term side effects and treatment duration.
3 citations
,
January 2022 in “Journal of The American Academy of Dermatology” 1 mg/day of low-dose oral minoxidil is effective and safe for treating female hair loss.
39 citations
,
September 2000 in “Obstetrics and Gynecology Clinics of North America” Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.
October 2023 in “Pakistan Journal of Medical & Health Sciences” Men with hair loss often have abnormal cholesterol levels, so early screening is advised.
43 citations
,
July 2005 in “Journal of Chromatography B” A new method accurately measures hair lipids, revealing individual differences.
1 citations
,
April 2021 in “Journal of Cosmetic Dermatology” The cream effectively reduced hair growth on forearms.
2 citations
,
January 2023 in “Uro” UHP-sCESr is as effective as HESr for treating BPH symptoms.
6 citations
,
October 2014 in “Endokrynologia Polska” Excessive hair growth is much more common in Chinese women with PCOS than in the general population.
February 2024 in “Bioengineering” The hydrogel made of chitosan, HPMC, and insulin speeds up wound healing and could be a new dressing, especially for diabetics.
40 citations
,
November 2013 in “European journal of endocrinology” Effective hirsutism treatment for women with PCOS should be personalized and may include lifestyle changes and medication.
1 citations
,
April 1976 in “Archives of Dermatology” Sudden weight loss can cause significant hair loss, and using colchicine on the skin for psoriasis may be unsafe.