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August 1997 in “Microscopy Research and Technique” New molecules involved in skin and hair growth were identified, improving understanding and future treatments.
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November 2020 in “Nature Communications” Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
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January 2016 in “Open Journal of Regenerative Medicine” Myoblast transplantation shows promise for treating various muscle and heart conditions.
37 citations
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January 2022 in “Frontiers in Genetics” Aging reduces dermal sheath cells, affecting youthful skin appearance.
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February 2023 in “Stem Cell Research & Therapy” Mouse skin cells can become sperm-like cells in the lab.
24 citations
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April 2012 in “Developmental Biology” Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists created a new 3D skin model from cells of plucked hairs that works like real skin and is easier to get.
83 citations
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May 2013 in “International Journal of Molecular Sciences” Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
50 citations
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November 2010 in “Tissue Engineering Part A” Hair follicle cells and intestinal tissue can create strong, functional blood vessel replacements.
68 citations
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December 2011 in “Journal of Investigative Dermatology” Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
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April 2010 in “Cellular Reprogramming” Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
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September 2016 in “PLoS ONE” Cell division orientation varies by body site and is linked to epidermal thickness and cell density.
December 2004 in “Differentiation”
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December 2016 in “PloS one” A specific protein in chicken embryos links early skin layers to feather development.
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February 2011 in “Cell” Nephronectin helps attach muscle cells to hair follicles.
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February 2025 in “International Journal of Molecular Sciences” Enzymatic digestion is an efficient method for isolating cells from hair follicles for tissue-engineered skin.
August 2023 in “Journal of Investigative Dermatology” Skin organoids can regenerate hair by forming specific cell units with certain signals.
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January 1998 in “EXPERIMENTAL ANIMALS” The skin of both rat strains showed similar lectin binding patterns.
February 2025 in “Animals” Understanding proteins in skin structures like claws and hair is crucial for future research.
418 citations
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September 2012 in “Nature” African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.
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December 2014 in “Scanning” Multiphoton microscopy effectively images rabbit skin structures in detail without staining and shows differences from human skin.
277 citations
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July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
43 citations
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February 2008 in “Journal of cutaneous pathology” Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
106 citations
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April 1986 in “British Journal of Dermatology” Dermal papilla cells from human hair follicles form unique structures and don't live as long as other skin cells in lab conditions.
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September 1980 in “Zoological Journal of the Linnean Society” Dendritic cells help regulate skin development and hair growth in mice.
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April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
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May 2016 in “Journal of dermatology” Tissue expansion successfully treated alopecia in a child with hypohidrotic ectodermal dysplasia.
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January 2023 in “PubMed”
23 citations
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November 2018 in “Development, Growth & Differentiation” Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.
11 citations
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January 2010 in “Dermatology Research and Practice” Desmosomes are crucial for human skin development, increasing in density as the skin matures.