88 citations
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May 2020 in “Clinical therapeutics” Stress can worsen skin diseases by affecting immune cells, hormones, and neurotransmitters in the skin.
81 citations
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July 2008 in “The Journal of Clinical Endocrinology and Metabolism” Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
67 citations
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July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
61 citations
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September 2010 in “Journal of Dermatological Science” Stress hormones and autoimmune reactions can cause hair loss.
61 citations
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March 2003 in “American Journal Of Pathology” Stress can cause hair loss and skin issues by affecting hair growth cycles.
56 citations
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November 2010 in “Pigment Cell & Melanoma Research” Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
54 citations
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November 1995 in “The Journal of Clinical Endocrinology & Metabolism” Females with 5 alpha-reductase-2 deficiency have less body hair, no acne, normal fertility, and delayed menarche.
52 citations
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June 2013 in “The Journal of Clinical Endocrinology and Metabolism” The research found that anovulatory young women have higher androgen and hormone levels than those who ovulate, suggesting immature hormonal regulation rather than a specific condition.
50 citations
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July 2018 in “Psychoneuroendocrinology” Hair cortisol can indicate long-term stress levels, but hair growth rate differences may affect accuracy.
38 citations
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April 2018 in “Psychopharmacology/Psychopharmacologia” Blocking CRF-R1 can reduce alcohol intake in stressed mice.
34 citations
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April 2014 in “Psychopharmacology” Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.
30 citations
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November 2021 in “Obesity Reviews” Higher glucocorticoids in hair are linked to increased obesity measures like waist size.
26 citations
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January 1982 in “Hormone Research” Normal androgen levels need ACTH, and different mechanisms control adrenarche and gonadarche.
24 citations
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October 2018 in “Addiction Biology” Alcohol dependence affects stress hormone levels more than childhood maltreatment.
23 citations
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January 2016 in “Brazilian Journal of Psychiatry” First-episode psychosis patients have higher hair cortisol levels, indicating early stress response issues.
22 citations
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November 2007 in “Journal of Investigative Dermatology Symposium Proceedings” Hair growth and health are influenced by stress and hormones.
18 citations
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August 2012 in “Cutaneous and Ocular Toxicology” People with alopecia areata have higher insulin resistance.
16 citations
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May 2020 in “Psychoneuroendocrinology” People with Parkinson's disease have higher levels of cortisone in their hair, which may indicate chronic stress hormone dysfunction.
14 citations
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September 2015 in “Expert Opinion on Therapeutic Targets” The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
10 citations
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May 2020 in “Advances in Polymer Technology” Melatonin-loaded nanoparticles improve antidepressant effects and HPA hormone balance better than regular melatonin.
7 citations
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March 2022 in “Journal of the American Academy of Dermatology” Stress can trigger or worsen alopecia areata.
7 citations
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December 2011 in “InTech eBooks” Glucocorticoid and mineralocorticoid therapy effectively manage Congenital Adrenal Hyperplasia symptoms but have limitations.
7 citations
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October 2010 in “Medical Hypotheses” Alopecia areata may involve stress-related changes affecting hormone receptors, leading to reduced cortisol production.
3 citations
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January 2017 in “Journal of clinical and diagnostic research” Injecting steroids like Triamcinolone Acetonide for skin treatments can cause Cushing's Syndrome.
2 citations
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June 2022 in “Scientific reports” Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.
2 citations
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November 2011 in “InTech eBooks” Stress can worsen skin conditions by affecting immune responses and skin cell activities.
1 citations
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February 2023 in “Drug Design Development and Therapy” Plant adaptogens may help treat skin diseases and improve skin health, but more research is needed to fully understand how they work.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Alopecia affects mental health, causing depression and anxiety, but new treatments can improve both hair growth and quality of life.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Alopecia affects mental health, causing depression and anxiety, but new treatments can help improve both hair growth and quality of life.
July 2025 in “International Journal of Dermatology Venereology and Leprosy Sciences” Higher stress levels may worsen alopecia areata, suggesting stress management is important for treatment.