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Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

Infants with severe KID syndrome may be more prone to serious infections and need close monitoring.

A bull with a gene mutation was asymptomatic, synthetic retinoids cause hair loss, and new therapeutic targets were identified for skin diseases.

A new gene mutation causes vitamin D resistance and rickets, treatable with calcium therapy.

Mouse high-glycine/tyrosine proteins have distinct patterns in hair follicles, peaking at specific hair cycle days.

A genetic mutation caused severe rickets and alopecia in an Indian patient, but high-dose calcium and phosphate treatment improved their condition.

Ptprq has multiple forms that change during inner ear development.

A variant in the ADAM17 gene causes hair loss by increasing protein degradation through TRIM47.

The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.

A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.

Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.

The PP2A-B55α protein is essential for brain and skin development in embryos.

Removing STAT5 from 3D-cultured human skin cells reduces their ability to grow hair.

LHX2 is essential for hair follicle development, controlled by NF-κB and TGFβ2 signaling.

Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Different mutations in the 5 alpha-reductase-2 gene were found in affected individuals in the Dominican Republic, suggesting no common ancestry.

Personalized sonidegib dosing can effectively treat Gorlin-Goltz syndrome with fewer side effects.

Certain variations in the vitamin D receptor gene are linked to an increased risk of polycystic ovary syndrome.

Removing part of the vitamin D receptor stops vitamin D from working properly.

DNA phenotyping can predict physical traits like eye, hair, and skin color, improving forensic investigations.

NDRG1 protein helps infantile hemangioma, a common infant tumor, to grow, and its mismanagement by FOXO1 protein plays a big role in causing the tumor.

Acidic keratin genes are on CFA9 and basic keratin genes are on CFA27 in dogs.

Sheep have 17 keratin genes, similar to humans, but with different expression patterns affecting wool and hair.

TGFβ-2 may cause hair loss in androgenetic alopecia.

2-deoxy D-glucose does not help with hair regrowth in alopecia areata.

Keratins are crucial for cell structure, growth, and disease risk.

Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.