49 citations
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December 1997 in “Urology” Tamoxifen effectively treats gynecomastia without causing impotence.
49 citations
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November 1992 in “Archives of dermatology” Different treatments for alopecia areata have varying success rates and side effects; intralesional steroids are most effective.
49 citations
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January 2004 in “Dermatology” Men with a family history of hair loss are more likely to experience it themselves, especially if both parents have hair loss.
48 citations
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July 1996 in “Human & Experimental Toxicology” Human enzymes can detoxify harmful substances but might also increase their cancer risk.
48 citations
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October 2014 in “International Journal of Cardiology” People with alopecia are at higher risk for heart disease and have more heart-related risk factors.
48 citations
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February 2013 in “Molecular and Cellular Endocrinology” The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
47 citations
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April 2000 in “The American journal of pathology” Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.
46 citations
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December 2001 in “Journal of Endocrinology/Journal of endocrinology” FLRG and follistatin have different roles in wound healing.
45 citations
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February 2001 in “Joint bone spine” Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.
44 citations
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August 2012 in “Journal of Food Science” The best way to extract saponins from Eclipta prostrasta is using 70% ethanol, at 70°C for 3 hours with a 14:1 liquid to solid ratio.
43 citations
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September 2001 in “Scanning” Hair treatments like bleaching increase friction by exposing tiny pores on the hair surface.
41 citations
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October 2008 in “The American journal of pathology” Blocking a specific protein signal can make hair grow on mouse nipples.
41 citations
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June 2018 in “Medicine Health Care and Philosophy” The article suggests using four questions to tell apart necessary medicalization from excessive medicalization, focusing on problem significance, social expectations, medical understanding, and effective resolution.
41 citations
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October 2012 in “Australian and New Zealand Journal of Psychiatry” Negative expectations can cause adverse effects in patients even without active treatment, and managing this nocebo effect involves better communication and patient-clinician relationships.
40 citations
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August 2018 in “Skin appendage disorders” Some alternative treatments for hair loss might work, but more research is needed.
40 citations
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January 2013 in “Frontiers in Endocrinology” Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.
39 citations
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April 2020 in “Clinical, Cosmetic and Investigational Dermatology” Asian hair is generally straight and thick, with unique disorders and properties, and more research is needed to understand it fully.
39 citations
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October 2010 in “Journal of The American Academy of Dermatology” Some patients with mycosis fungoides or Sézary syndrome experience hair loss, which may be similar to alopecia areata or linked to skin lesions, possibly due to abnormal T cells, and bexarotene can help treat it.
39 citations
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April 2010 in “International Journal of Pharmaceutics” Nanoparticles improve minoxidil skin permeation, but more research needed for effective hair growth.
39 citations
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November 1984 in “Journal of Cardiovascular Pharmacology” Minoxidil lowers blood pressure, increases heart rate, and improves blood flow in dogs.
38 citations
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October 1996 in “Dermatologic Clinics” Certain hormone treatments can improve acne and related conditions in women.
37 citations
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April 2019 in “Journal of The American Academy of Dermatology” Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.
37 citations
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June 2018 in “Clinical and Experimental Medicine” People with alopecia areata often have lower vitamin D levels and more inflammation, suggesting vitamin D might be involved in the condition.
37 citations
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October 2015 in “Anais Brasileiros de Dermatologia” Lichen planopilaris mostly affects women with fair skin and can look different on each person, needing early treatment to prevent hair loss.
36 citations
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November 2005 in “Journal of The American Academy of Dermatology” Topical latanoprost doesn't effectively regrow hair in severe eyebrow alopecia areata cases.
36 citations
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September 2001 in “Journal of The European Academy of Dermatology and Venereology” Finasteride doesn't reduce sexual function in people with hair loss.
35 citations
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August 1980 in “Circulation” Minoxidil may cause heart issues in animals and humans.
33 citations
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July 1992 in “Journal of Investigative Dermatology” Minoxidil doesn't affect perifollicular lymphoid infiltration in alopecia areata patients.
31 citations
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January 2018 in “Pediatric annals” Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.
31 citations
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March 2018 in “Frontiers in Immunology” The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.