research Composite Hydrogel Based on Green Chlorella Polysaccharide–Selenium Nanoparticles for Simultaneous Wound Treatment and pH Monitoring
The hydrogel speeds up wound healing, fights bacteria, reduces inflammation, and monitors pH.
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research 25 years of ERβ: a personal journey
ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
research Evaluation of hydro-alcoholic extract of Eclipta alba for its anticancer potential: An in vitro study
Eclipta alba extract shows potential as an anticancer agent by inhibiting cancer cell growth and promoting cell death.
research Physicochemical evaluation of Prinsepia utilis seed oil (PUSO) and its utilization as a base in pharmaceutical soap formulation
Prinsepia utilis seed oil is suitable for making pharmaceutical soap.
research Comparative Study on Antioxidant Potential of Schinus terebinthifolius Extracts Prepared by Conventional Extraction, Accelerated Solvent Extraction, and Pulsed Electric Field Method
The conventional extraction method with 50% ethanol was the most effective for antioxidant activity.
research Cepharanthine: An update of its mode of action, pharmacological properties and medical applications
Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.
research Epigenetic regulation and factors that influence the effect of iPSCs-derived neural stem/progenitor cells (NS/PCs) in the treatment of spinal cord injury
Epigenetic factors affect the success of using iPSC-derived cells for spinal cord injury treatment.
research 5. 周産期チーム医療におけるソーシャルワークの役割 : 子どもと家族のしあわせへの貢献をチームで目指す中で(メインシンポジウム これからの周産期チーム医療の展開,第50回日本母性衛生学会総会)
DPC-Exos can help regenerate hair follicles and heal wounds by activating the Wnt/β-catenin pathway.
research Feasibility of repairing full-thickness skin defects by iPSC-derived epithelial stem cells seeded on a human acellular amniotic membrane
iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.
research Intraepidermal Injections of Autologous Epidermal Cell Suspension: A new promising approach to Dermatological Disorders. Preliminary Study
Injecting a person's own skin cells back into their skin is a promising, safe, and affordable treatment for skin disorders.
research A pilot study evaluating dosing tolerability of 17α-estradiol in male common marmosets (Callithrix jacchus)
research 459 Estetrol prevents catagen progression in healthy and female pattern hair loss hair follicles ex vivo
Estetrol may help prevent hair loss and support hair growth in women.
research Vertebral epidermal transamidases
Transamidases are present in the epidermis but their exact role is unclear.
research Systematically optimized coenzyme q10-loaded novel proniosomal formulation for treatment of photo-induced aging in mice: characterization, biocompatibility studies, biochemical estimations and anti-aging evaluation
The new CoQ10 gel protects mouse skin better against aging from UV light than the old gel.
research A case report of inflammatory nonscarring alopecia associated with the epidermal growth factor receptor inhibitor erlotinib
Erlotinib can cause nonscarring hair loss and itchy skin.
research Olfactory epithelium regeneration and homeostasis: cellular and molecular mechanisms and novel methodological advances
The olfactory epithelium (OE) exhibits lifelong neurogenesis and robust regenerative abilities through the roles of horizontal basal cells (HBCs) and globose basal cells (GBCs), regulated by transcription factors like Sox2, p63, Pax6, Ascl1, Neurog1, and NeuroD1, along with signaling pathways such as Wnt/β-catenin, Notch, YAP, and inflammation-related regulators. Genes like Lgr5, Tmem59, Notch1, and Chil4 are crucial for OE homeostasis and regeneration within a dynamic network. Advances in single-cell and spatial transcriptomics, as well as organoid models, have uncovered new cell states and differentiation pathways, enhancing the understanding of OE regeneration and informing future strategies for olfactory function restoration.
research 713 Fisetin promotes differentiation, inhibits proliferative and inflammatory responses in cultured human cells and alleviates psoriasiform dermatitis in mice
Fisetin may help treat psoriasis and reduce skin inflammation.
research Application of Niosomes in Cosmetics: A Systematic Review
Niosomes improve the effectiveness of skin and hair cosmetics.
research Dermatopathology and molecular genetics
Combining skin tissue pathology with genetics has greatly improved the diagnosis and understanding of certain skin diseases.
research Photobiomodulation in 3D tissue engineering
PBM helps improve cell survival in 3D tissue engineering.
research Cyproterone acetate for hirsutism
Cyproterone acetate with estradiol may subjectively improve excessive hair growth in women, but it's not clinically better than other treatments.
research Engineered Exosomes Co-Delivering EGF and FGF Ameliorate Androgenetic Alopecia in a Mouse Model
Engineered exosomes with EGF and FGF improve hair growth in mice with hair loss.
research Chronic Pancreatitis and Persistent Steatorrhea: What Is the Correct Dose of Enzymes?
Enzyme doses for chronic pancreatitis should match meal size, not patient size.
research Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases
Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
research Alginate-Based Cryogels for Combined Chemo/Photothermal Antibacterial Therapy and Rapid Hemostasis
SEF cryogels effectively kill bacteria, stop bleeding, and speed up wound healing.
research Intravital imaging of host–parasite interactions in skin and adipose tissues
Intravital microscopy helps us see how parasites interact with skin and fat in living animals.
research RSPO1, a potent inducer of pancreatic β cell neogenesis
RSPO1 could help create new diabetes treatments by increasing pancreatic β cells.
research Generating Disulfides in Multicellular Organisms: Emerging Roles for a New Flavoprotein Family
QSOX enzymes help form protein bonds in cells, especially in tissues with high secretory activity.
research Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex
Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.