36 citations
,
July 2007 in “Journal of Investigative Dermatology” Certain HLA class II alleles increase or decrease the risk of alopecia areata.
Atopy and altered T cell functions contribute to Alopecia Areata.
19 citations
,
February 2016 in “Journal of The American Academy of Dermatology” CD3+ T-cell presence is a reliable marker to tell apart alopecia areata from pattern hair loss.
20 citations
,
September 2003 in “Journal of Investigative Dermatology” Targeting MIG and MCP-1 may help treat inflammation in alopecia areata.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The ALADIN score can predict how well patients with alopecia areata will respond to JAK inhibitor treatments.
August 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” TAGX-0003 protected hair follicles and reversed alopecia areata in a mouse model.
July 2025 in “Foundation University Journal of Dentistry” Alopecia areata patients often have autoimmune disorders, especially thyroid issues.
September 2024 in “Cureus” Early detection and targeted management are crucial for better outcomes in systemic lupus erythematosus.
July 2024 in “Journal of Investigative Dermatology” The Fas/FasL pathway may play a role in alopecia areata.
2 citations
,
October 1990 in “PubMed” Severe alopecia areata involves higher levels of certain immune cells, which can be normalized with betamethasone.
22 citations
,
January 2017 in “Acta Endocrinologica” A woman with multiple autoimmune diseases showed improvement in hair loss but not in skin discoloration after treatment.
1 citations
,
October 2025 in “Journal of Allergy and Clinical Immunology” A JAK1 variant causes hair loss, skin issues, and thyroid disease, but treatment with a specific inhibitor can help.
November 2025 in “Skin Appendage Disorders” Immune cell-targeting biologics show potential for treating alopecia areata but need better-targeted therapies.
May 2025 in “International Journal of Dermatology” Alopecia areata patients are more likely to develop systemic lupus erythematosus.
1 citations
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January 2015 in “General Medicine” Vitiligo and alopecia areata might be early signs of Type 1 Diabetes.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers found that certain miRNAs, which affect immune system regulation, are differently expressed in mice with a hair loss condition compared to healthy mice.
23 citations
,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” Genetic discoveries are leading to new treatments for alopecia areata.
November 2023 in “Ibrahim Cardiac Medical Journal” Alopecia areata patients are more likely to have thyroid disorders than healthy individuals.
2 citations
,
March 2023 in “3C Empresa Investigación y pensamiento crítico” Alopecia areata patients have higher IFN-γ and low vitamin D3 levels.
8 citations
,
June 2012 in “Journal of Crohn s and Colitis” Managing multiple autoimmune diseases in one patient is extremely challenging.
164 citations
,
November 1989 in “Clinical and Experimental Dermatology” Juvenile alopecia areata is more severe and has a worse prognosis than maturity-onset alopecia areata.
21 citations
,
January 2021 in “Journal of infection and chemotherapy” Men, diabetes, and high inflammation levels lead to higher COVID-19 antibodies.
May 2025 in “International Journal of Dermatology” 71 citations
,
February 1992 in “Journal of Cutaneous Pathology” Antibodies help identify glycoproteins in normal skin and tumor cells.
May 2024 in “Drugs & Therapy Perspectives” New treatments like JAK inhibitors offer hope for better alopecia areata management.
August 2021 in “BMJ Case Reports” A woman with lupus had blood cell destruction, treated successfully with medication.
Higher PD-1 levels mean fewer CD8+ T cells in alopecia areata hair follicles.
April 2018 in “Journal of Investigative Dermatology” Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.
23 citations
,
September 2020 in “Journal of Dermatological Science” Targeting Vδ1+T-cells may help treat alopecia areata.
January 2025 in “Dermatologic Therapy” Alopecia areata may be linked to higher heart disease risk.