August 2014 in “Warwick Research Archive Portal (University of Warwick)” Obesity negatively affects the endometrium, leading to higher miscarriage risk and impaired cell function.
Older age, obesity, hirsutism, and having children increase metabolic risk in women with PCOS.
Metformin is safe in early pregnancy for women with PCOS and may reduce certain risks.
Obesity is linked to many gastrointestinal diseases and needs more research for treatment development.
Hair follicles can be used to quickly assess drug effects in cancer treatment.
May 2010 in “Current Women's Health Reviews” The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.
January 2009 in “Elsevier eBooks” Some plant-based treatments may help with ovary function, insulin resistance, and excess male hormones in PCOS, but more research is needed to confirm their safety and effectiveness.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
TGF-β1 and 2 in hair follicles may be linked to hair loss in AGA.
98 citations
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November 1999 in “Dermatology Online Journal” IGF-1 can boost hair growth by promoting cell growth and preventing cell death.
1 citations
,
January 2022 in “Annals of Dermatology” A new mutation in the MBTPS2 gene causes a mild form of IFAP syndrome.
June 2023 in “Medical records-international medical journal” Decreased IGF-1R expression may contribute to sacrococcygeal pilonidal sinus development.
April 2018 in “Journal of Investigative Dermatology” Fgf20 is important for the development and regulation of the cells that form the base of hair follicles.
August 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” FGF18 controls hair cycle rest and growth phases.
28 citations
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November 2013 in “Cell and Tissue Research” July 2025 in “Journal of Investigative Dermatology” Nelfb is essential for dermal fat development and survival.
1 citations
,
September 2025 in “Frontiers in Immunology” Folate receptor β helps suppress the immune system in macrophages and affects cancer growth and hair health.
2 citations
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July 2023 in “Animals” FGF10 and non-coding RNAs are important for cashmere goat hair follicle development.
December 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” Endoglin is important for proper hair growth cycles and stem cell activation in hair follicles.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Transglutaminase 2 may control sebocyte maturation and lipid metabolism.
44 citations
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July 1993 in “Journal of Investigative Dermatology”
12 citations
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February 1998 in “Gene” The B2 genes are crucial for hair growth in rats.
94 citations
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March 1996 in “Journal of Investigative Dermatology”
1 citations
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August 2022 in “International Journal of Molecular Sciences” FGF12 is important for hair growth and could be targeted for hair loss treatment.
March 2026 in “Journal of Investigative Dermatology” Folliculin slows hair growth, and blocking it might help treat hair loss.
GPC1 is important for blood vessel growth in hair follicles and could help treat hair loss.
150 citations
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June 1999 in “Oncogene”