20 citations
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January 2017 in “Scientific reports” Whale genes show changes that help them live in water, like less hair and better flippers.
TGF-β1 and 2 in hair follicles may be linked to hair loss in AGA.
10 citations
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February 2019 in “Journal of cellular physiology” TGF-β2 helps yak hair follicles enter the regression phase, while HSP70 tries to prevent it.
1 citations
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March 2023 in “Science Translational Medicine” Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.
GPC1 is important for hair growth by helping blood vessels form around hair follicles.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.
May 2021 in “FEBS open bio” 7 citations
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November 1997 in “Reproduction Fertility and Development” Epidermal growth factor disrupts hair and gland formation in bandicoots.
October 2015 in “Regenerative Medicine” Two growth factors, PDGF and FGF2, can potentially be used together to grow enough cells for a hair loss treatment, but their exact function on human cells needs further confirmation.
19 citations
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January 2019 in “Animals” PDGFA helps activate hair growth in cashmere goats.
103 citations
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February 1972 in “Proceedings of the National Academy of Sciences” A unique enzyme in guinea pig hair follicles helps form protein cross-links in hair.
January 2008 in “Memorial University Research Repository (Memorial University)” Pygopus 2 helps ovarian cancer cells grow by aiding ribosomal RNA production, independent of Wnt signaling.
54 citations
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April 2019 in “Journal of cellular physiology” miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.
136 citations
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June 2006 in “Journal of Dermatological Science” PDGF isoforms can promote and sustain hair growth.
55 citations
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October 2008 in “American Journal Of Pathology” mIGF-1 in skin cells speeds up wound healing and hair growth in mice without harmful effects.
June 2023 in “Medical records-international medical journal” Decreased IGF-1R expression may contribute to sacrococcygeal pilonidal sinus development.
Knocking out the FGF5 gene in sheep increased wool production and hair-follicle density.
4 citations
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April 2024 in “Cellular and Molecular Biology” Injectable platelet-rich fibrin is better than platelet-rich plasma for promoting hair growth.
June 2024 in “Archives of Dermatological Research” SFRP2 and PTGDS may be key factors in female hair loss.
1 citations
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December 2021 in “Development & Reproduction” Lack of FPR2 slows hair growth by affecting hair cell activity.
55 citations
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September 2003 in “Experimental Dermatology” PDGF signaling may play a role in hair growth cycle regulation.
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June 2023 in “BMC genomics” A specific gene mutation causes long hair in Angora rabbits.
August 2013 in “Nature Reviews Drug Discovery” A protein called FGF9 helps regenerate hair follicles in mice after skin damage, and increasing FGF9 could potentially help human hair growth.
December 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” Endoglin is important for proper hair growth cycles and stem cell activation in hair follicles.
1 citations
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September 2016 in “Journal of Dermatological Science” FGF18 treatment during hair's resting phase can protect against hair loss from radiation.
52 citations
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April 2013 in “Developmental Cell” Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.
November 2022 in “Journal of Investigative Dermatology” ILC1-like cells can cause alopecia areata by themselves.
15 citations
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March 2007 in “BioTechniques” The assay quickly identifies substances that increase or decrease blood vessel growth.
12 citations
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September 2018 in “Journal of Drug Delivery Science and Technology” The silk fibroin hydrogel with FGF-2-liposome can potentially treat hair loss in mice.
31 citations
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February 2014 in “Journal of dermatological science” Placental growth factor may help treat hair loss.