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research TGFβ‐mediated inhibition of hypodermal adipocyte progenitor differentiation promotes wound‐induced skin fibrosis

3 citations , July 2024 in “Cell Proliferation”

Blocking TGFβ can help treat fibrotic skin conditions by promoting fat cell formation.

research Altered FGF expression profile in human scalp-derived fibroblasts upon WNT activation: implication of their role to provide folliculogenetic microenvironment

17 citations , September 2020 in “Inflammation and Regeneration”

WNT activation in scalp fibroblasts boosts hair growth by increasing FGF9.

research Four Independent Mutations in the Feline Fibroblast Growth Factor 5 Gene Determine the Long-Haired Phenotype in Domestic Cats

75 citations , September 2007 in “Journal of Heredity”

FGF5 gene mutations cause long hair in domestic cats.

research NFIC promotes the vitality and osteogenic differentiation of rat dental follicle cells

11 citations , August 2019 in “Journal of Molecular Histology”

NFIC helps rat dental cells grow and turn into bone-like cells.

research BMP4 and nuclear laminC orchestrate a expression of AHF/Trichohyalin molecule, a key modulator of keratin intermediate filaments in the hair follicle

January 2007

research Fibroblast growth factor 21 is differentially expressed in flank skin and regulates the proliferation of hair follicles in yak

April 2026 in “Gene”

research Inhibition of a signaling modality within the gp130 receptor enhances tissue regeneration and mitigates osteoarthritis

1 citations , March 2023 in “Science Translational Medicine”

Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.

research Transglutaminase 5 Expression in Human Hair Follicle

28 citations , August 2005 in “Journal of Investigative Dermatology”

TG5 helps maintain hair follicle health, while TG3 aids in hair shaft development.

Branching of Spiral Ganglion Neurites Induced by Focal Application of Fibroblast Growth Factor-1

research Branching of Spiral Ganglion Neurites Is Induced by Focal Application of Fibroblast Growth Factor‐1

15 citations , May 2003 in “The Laryngoscope”

FGF-1 causes spiral ganglion neurites to branch more.

research Exogenous IGF-1 promotes hair growth by stimulating cell proliferation and down regulating TGF-β1 in C57BL/6 mice in vivo

53 citations , March 2014 in “Growth Hormone & IGF Research”

IGF-1 injections help mice grow more hair by increasing cell growth and blocking a hair growth inhibitor.

research
Discovery of Four New FGF5 Variants Causing Long Hair in the Dog

January 2026 in “Preprints.org”

Four new FGF5 gene variants cause long hair in dogs.

research Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling

158 citations , February 2012 in “Journal of Investigative Dermatology”

FGF18 helps keep hair in its resting phase, affecting hair growth cycles.

research Issue Information

May 2021 in “FEBS open bio”

research Possible involvement of 5α-reduced neurosteroids in adrenergic and serotonergic stimulation of GFAP gene expression in rat C6 glioma cells

17 citations , April 2006 in “Brain Research”

5α-reduced neurosteroids may help regulate glial cell differentiation.

research Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis

47 citations , September 2012 in “Human molecular genetics online/Human molecular genetics”

Folliculin deficiency causes problems with cell division and positioning due to disrupted RhoA signaling and interaction with p0071.

research Telogen Phase of Hair Growth Cycle Is Regulated by Cyclic Epithelial FGF18 Signaling

1 citations , December 2012 in “Journal of Dermatological Science”

FGF18 controls hair growth rest phase.

research Coordinating Stem Cell Behavior in the Hair Follicle

September 2025 in “Digital Commons - RU (Rockefeller University)”

Nfib in hair follicle stem cells boosts melanocyte stem cell growth and differentiation.

research Analysis of the FGF gene family provides insights into aquatic adaptation in cetaceans

20 citations , January 2017 in “Scientific reports”

Whale genes show changes that help them live in water, like less hair and better flippers.

research Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis

252 citations , March 1998 in “Developmental dynamics”

FGFs-4, -8, and -9 have overlapping roles and are repeatedly used in tooth development.

research Regulation of a hair follicle keratin intermediate filament gene promoter

39 citations , December 1998 in “Journal of Cell Science”

The LEF-1 binding site enhances gene expression in hair follicles, with other proteins aiding specific regulation.

Fibroblast Growth Factors Stimulate Hair Growth Through Beta-Catenin and Shh Expression in C57BL/6 Mice

research Fibroblast Growth Factors Stimulate Hair Growth throughβ-Catenin and Shh Expression in C57BL/6 Mice

64 citations , January 2015 in “BioMed Research International”

Certain growth factors can promote hair growth in mice by activating hair growth-related proteins.

research Purification and characterization of an immuno-stimulatory compound from the water extract of royoporus badius (Pers.) A.B. De.

January 2018

A new compound from Royoporus badius activates immune cells and induces inflammatory responses.

research Effect of oleuropein on mRNA and protein expression of growth factors in C57BL/6N mouse skin tissue.

December 2015 in “OPAL (Open@LaTrobe) (La Trobe University)”

Oleuropein increases IGF-1 levels in mouse skin.

research Suppression of Cutibacterium acnes-Mediated Inflammatory Reactions by Fibroblast Growth Factor 21 in Skin

7 citations , March 2022 in “International Journal of Molecular Sciences”

FGF21 can help reduce skin inflammation caused by C. acnes.

research Latent transforming growth factor beta-binding protein 1 (LTBP1): roles as a multifunctional extracellular matrix regulator in human disease. From molecular mechanisms to clinical translation prospects

March 2026 in “Folia Histochemica et Cytobiologica”

LTBP1 is a key regulator in diseases and a potential target for new treatments.

research Structure-guided PEGylated fibroblast growth factor 2 variants accelerate wound healing with improved stability

1 citations , May 2020

Compound 6 is a promising candidate for better wound healing.

research CRISPR/Cas9‐mediated loss of FGF5 function increases wool staple length in sheep

47 citations , June 2017 in “The FEBS journal”

Disabling the FGF5 gene in sheep leads to longer wool.

Crosstalk Between Androgen and Wnt/β-Catenin Leads to Changes in Wool Density in FGF5-Knockout Sheep

research Crosstalk between androgen and Wnt/β-catenin leads to changes of wool density in FGF5-knockout sheep

23 citations , May 2020 in “Cell Death and Disease”

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

research 1362 The role of Fgf20 in establishing the hair follicle dermal condensate

April 2018 in “Journal of Investigative Dermatology”

Fgf20 is important for the development and regulation of the cells that form the base of hair follicles.

research Signal transducer and activator of transcription 5B deficiency due to a novel missense mutation in the coiled-coil domain

14 citations , September 2018 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.

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