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research The structure of human trichohyalin. Potential multiple roles as a functional EF-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein

161 citations , June 1993 in “Journal of Biological Chemistry”

Trichohyalin helps in hair and skin cell structure and function by binding calcium and linking proteins.

research Hirsutism and Quality of Life

January 2010 in “Springer eBooks”

Hirsutism can lower a woman's quality of life, causing emotional distress and affecting social and work opportunities.

research Human iPS Cell-Derived Cell Aggregates Exhibited Dermal Papilla Cell Properties in in vitro Three-Dimensional Assemblage Mimicking Hair Follicle Structures

10 citations , August 2021 in “Frontiers in cell and developmental biology”

Scientists made structures that look like human hair follicles using stem cells, which could help grow hair without using actual human tissue.

research In Vitro Assembly and Structure of Trichocyte Keratin Intermediate Filaments

91 citations , December 2000 in “The journal of cell biology/The Journal of cell biology”

Scientists successfully created mouse hair proteins in the lab, which are stable and similar to natural hair.

research The Intermediate Filament Architecture as Determined by X-Ray Diffraction Modeling of Hard α-Keratin

66 citations , June 2004 in “Biophysical Journal”

Hard α-keratin in hair has a unique, nonordered structure, different from other fibers.

research Cutaneous Ultrastructural Features of the Flaky Skin (fsn) Mouse Mutation

28 citations , June 1995 in “The Journal of Dermatology”

The flaky skin mouse mutation is a natural model for studying human psoriasis.

Optimization and Characterization of a Focal Dermal Hypoplasia Mouse Model to Test Potential Treatments

research 1465 Optimization/characterization of a Focal Dermal Hypoplasia mouse model to test potential treatments

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Li2CO3 improved skin disease in a mouse model of Focal Dermal Hypoplasia without toxicity.

research Further Clinical Evidence for the Effect of IGF-1 on Hair Growth and Alopecia

29 citations , August 2017 in “Skin appendage disorders”

IGF-1 may affect hair growth and loss, but more research is needed to confirm effective and safe treatments.

research The Efficacy and Safety of AP-FHG0604T on Female Pattern Hair Loss: A Randomized Double-blind Placebo-controlled Clinical Trial

February 2007 in “Journal of Clinical Dermatology”

research A Mechanical-assisted Post-bioprinting Strategy for Challenging Bone Defects Repair

1 citations , September 2023 in “Research Square (Research Square)”

The new method improves bone repair by enhancing cell loading and stability in bioprinted scaffolds.

research An Extended Epidermal Response Heals Cutaneous Wounds in the Absence of a Hair Follicle Stem Cell Contribution

170 citations , November 2007 in “The journal of investigative dermatology/Journal of investigative dermatology”

Skin can heal wounds without hair follicle stem cells, but it takes a bit longer.

research Letters to the Editors: Re: Indian Association of Hair Restoration Surgeons

March 2009 in “Hair transplant forum international”

research 155 Exploring perceived quality of life in middle- to old-aged patients with inherited ichthyosis: a qualitative study

November 2024 in “Journal of Investigative Dermatology”

Inherited ichthyosis negatively impacts quality of life, affecting daily activities, self-image, and reproductive decisions.

research Pembrolizumab-Induced Autoimmune Hepatitis

October 2018 in “The American journal of gastroenterology”

Pembrolizumab can cause serious liver issues, requiring close monitoring and early treatment.

research WISP-1 induced by mechanical stress contributes to the fibrosis and hypertrophy of ligamentum flavum via the Hedgehog-Gli1 signaling

November 2020

Mechanical stress causes ligament thickening through WISP-1 and Hedgehog signaling.

research TOPICAL EFLORNITHINE TREATMENT FOR HIRSUTISM IN WOMEN: SUMMARY OF FINDINGS

June 2026 in “International Journal of Innovative Technologies in Social Science”

Topical eflornithine is an effective treatment for hirsutism in women, significantly reducing facial hair growth and improving quality of life. The study, which involved a systematic literature review of articles from 2001 to 2006, found that eflornithine works well both as a standalone treatment and when combined with laser or intense pulsed light therapies. The review also assessed the pharmacokinetics and safety of eflornithine, supporting its use as a beneficial intervention for managing hirsutism.