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research Cashmere growth control in Liaoning cashmere goat by ovarian carcinoma immunoreactive antigen-like protein 2 and decorin genes

7 citations , March 2018 in “Asian-Australasian journal of animal sciences”

OCIAD2 and DCN genes affect hair growth in goats by having opposite effects on a growth signaling pathway and inhibiting each other.

Cloning of Wrinkle-Free, a Previously Uncharacterized Mouse Mutation, Reveals Crucial Roles for Fatty Acid Transport Protein 4 in Skin and Hair Development

research Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development

93 citations , April 2003 in “Proceedings of the National Academy of Sciences of the United States of America”

Fatty acid transport protein 4 is essential for skin and hair development.

research Plakophilin 1 suppresses keratinocyte innate immune responses through DExD/H helicases

December 2025

Plakophilin 1 helps control skin cell immune responses to prevent excessive inflammation.

Case Report: Exploring Autosomal Recessive Woolly Hair: Genetic and Scanning Electron Microscopic Perspectives on a Japanese Patient

research Case report: Exploring autosomal recessive woolly hair: genetic and scanning electron microscopic perspectives on a Japanese patient

May 2024 in “Frontiers in medicine”

A genetic mutation in the LIPH gene causes tightly curled hair that stops growing in some Japanese individuals.

research Expression of the bcl-2 Protooncogene in the Cycling Adult Mouse Hair Follicle

122 citations , July 1994 in “Journal of Investigative Dermatology”

research 0866 Role of transcriptional elongation in dermal fat development

July 2025 in “Journal of Investigative Dermatology”

Nelfb is essential for dermal fat development and survival.

research 63418 JAK3/TEC kinase pathways are active in alopecia areata lesions, and their inhibition with Ritlecitinib prevents αCD3/αCD28+IL-2 induced immune privilege collapse in healthy hair follicles ex vivo

September 2025 in “Journal of the American Academy of Dermatology”

Ritlecitinib may help treat alopecia areata by protecting hair follicles.

research Effects of lncRNA MTC on protein expression in skin fibroblasts of Liaoning Cashmere goat based on iTRAQ technique

3 citations , September 2022 in “Animal biotechnology”

lncRNA MTC affects protein levels in goat skin cells, impacting hair growth.

research Selective JAK 1 inhibition with upadacitinib as a potential treatment for coexistent severe atopic dermatitis and alopecia areata

4 citations , February 2024 in “Anais Brasileiros de Dermatologia”

research Transgenic HPV11-E2 protein modulates URR activity in vivo

2 citations , February 2023 in “Transgenic Research”

The E2 protein affects gene activity in hair follicles of mice.

The Effect of JAK Inhibitor on Survival, Anagen Re-Entry, and Hair Follicle Immune Privilege Restoration in Human Dermal Papilla Cells

research The Effect of JAK Inhibitor on the Survival, Anagen Re-Entry, and Hair Follicle Immune Privilege Restoration in Human Dermal Papilla Cells

16 citations , July 2020 in “International Journal of Molecular Sciences”

Ruxolitinib may help treat hair loss by reducing inflammation, promoting hair growth signals, and protecting hair follicle immunity.

Neutralization of IL-8 Prevents Dermatologic Adverse Events Associated with Epidermal Growth Factor Receptor Inhibition

research Neutralization of IL-8 Prevents the Induction of Dermatologic Adverse Events Associated with the Inhibition of Epidermal Growth Factor Receptor

32 citations , June 2012 in “PLoS ONE”

Blocking IL-8 can reduce skin rashes from cancer treatment.

LRIG1 as a Positive Prognostic Marker in Merkel Cell Carcinoma and Expression of Epithelial Stem Cell Markers

research LRIG1 is a positive prognostic marker in Merkel cell carcinoma and Merkel cell carcinoma expresses epithelial stem cell markers

10 citations , July 2021 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin”

LRIG1 is linked to better survival in Merkel cell carcinoma.

research Comparative immunohistochemical analysis suggests a conserved role of EPS8L1 in epidermal and hair follicle barriers of mammals

1 citations , October 2023 in “PROTOPLASMA”

research LL-37 stimulates the functions of adipose-derived stromal/stem cells via early growth response 1 and the MAPK pathway

53 citations , April 2016 in “Stem cell research & therapy”

LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.

research Both Retinoic Acid Receptors α (RARα) and γ (RARγ) Are Able to Initiate Mouse Upper-Lip Skin Glandular Metaplasia

10 citations , August 1998 in “Journal of Investigative Dermatology”

research IL-1 Receptor–Knockout Mice Develop Epidermal Cysts and Show an Altered Innate Immune Response after Exposure to UVB Radiation

20 citations , July 2017 in “Journal of Investigative Dermatology”

IL-1 receptor absence in mice leads to skin cysts and changes in immune response after UVB exposure.

research Abstract 152

April 2015 in “Plastic and Reconstructive Surgery”

TLR3 activation helps improve skin and hair follicle healing in mice.

research 186 Mechanistic insights into Ritlecitinib-mediated immunomodulation in Alopecia Areata

November 2025 in “Journal of Investigative Dermatology”

research Cyclin-dependent kinase inhibitors, p21waf1/cip1 and p27kip1, are expressed site- and hair cycle-dependently in rat hair follicles

9 citations , February 2001 in “Journal of Dermatological Science”

p21waf1/cip1 and p27kip1 help in hair follicle differentiation in rats.

CircRNA-0100 Positively Regulates the Differentiation of Cashmere Goat SHF-SCs into Hair Follicle Lineage via Sequestering miR-153-3p to Heighten the KLF5 Expression

research CircRNA-0100 positively regulates the differentiation of cashmere goat SHF-SCs into hair follicle lineage via sequestering miR-153-3p to heighten the KLF5 expression

9 citations , February 2022 in “Archives animal breeding/Archiv für Tierzucht”

A circular RNA helps cashmere goat hair cells become hair follicles by blocking a molecule to boost a gene important for hair growth.

A Disease-Causing Novel Missense Mutation in the ST14 Gene Underlies Autosomal Recessive Ichthyosis with Hypotrichosis Syndrome in a Consanguineous Family

research A disease-causing novel missense mutation in the ST14 gene underlies autosomal recessive ichthyosis with hypotrichosis syndrome in a consanguineous family

9 citations , March 2018 in “European journal of dermatology/EJD. European journal of dermatology”

A new mutation in the ST14 gene causes a rare skin and hair disorder in a specific family.

Clinical Snippets: R-Spondin2 Amplifies Wnt Signaling for Hair Growth, Gene Expression Differences in Balding Scalp, IKB Regulates hBD2 in Psoriasis, ß-Defensin Gene Cluster and Hidradenitis Suppurativa, Autoantigen Epitopes in Alopecia Areata

research Clinical Snippets

July 2016 in “Experimental Dermatology”

New treatments for hair growth and psoriasis may be possible, and gene differences could affect baldness and the severity of skin conditions.

research Differential expression of type I IRS keratin genes in three breeds of sheep

January 2012 in “Zhongguo shouyi xuebao”

Sheep breeds show different keratin gene expression in the groin, linked to hair follicle density.

Understanding Immune Privilege in an Inducible Mouse Model of Primary Cicatricial Alopecia

research 175 Understanding immune privilege in an inducible mouse model of primary cicatrcial alopecia

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.

research Identification of lncRNAs involved in the hair follicle cycle transition of cashmere goats in response to photoperiod change

1 citations , May 2025 in “BMC Genomics”

lncRNAs may help control cashmere goat hair growth by responding to light changes.

research Autosomal Recessive Woolly Hair Caused by LIPH Mutations: A Case Series of Six Chinese Patients

November 2025 in “Clinical Cosmetic and Investigational Dermatology”

LIPH mutations cause woolly hair in some Chinese people.

research 092 Novel biallelic RIPK4 mutations cause ectodermal dysplasia with cutaneous syndactyly

September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

New RIPK4 gene mutations were found to cause a type of skin and limb birth defect.

research Author response: Involvement of ILC1-like innate lymphocytes in human autoimmunity, lessons from alopecia areata

February 2023

ILC1-like cells may contribute to hair loss in alopecia areata.

research Expression of truncated latent TGF-β-binding protein modulates TGF-β signaling

40 citations , May 2005 in “Journal of Cell Science”

Truncated LTBP-1 disrupts TGF-β signaling, affecting hair growth.

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