Search

everythinglearnresearchcommunity

for

Search:↓

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.

Targeting mTOR in myeloid cells may help reduce psoriasis symptoms.

IL-1β inhibits human hair follicle growth.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

IL-36α helps in growing new hair follicles when healing wounds, potentially aiding in hair growth.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Overexpressing 14-3-3σ in mice skin reduces cell growth and hair density.

The Lanceolate hair-J mutation in mice mimics human hair disorders like Netherton's syndrome.

The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.

The L412F variant of TLR3 is linked to skin infections, more viral infections, and autoimmune issues.

IL-15 helps maintain hair growth and protects the immune status of hair follicles.

HR protein causes abnormal hair cycles by increasing Tgf-β2 and reducing miR-31.

The study developed a mouse model for Alopecia Areata that responds to treatment, useful for future research.

Two mouse mutations cause similar hair loss despite different skin changes.

Aire mutation reduces alopecia areata, while Notch4 mutation prevents it in mice.

IL-13 protein is much higher in the skin of atopic dermatitis patients than in healthy skin.

IL-17 is more important than IFN-γ in causing severe hair loss in chronic alopecia areata.

Dual TCR Treg cells are common in mouse tissues and vary by location.

CD8+ T cells expand significantly in alopecia areata, suggesting new treatment targets.

Krt6a-Cre transgenic mice help study gene effects on hair follicle development and tumor suppression.

Overexpression of the HE4 gene in mice causes eye inflammation and cloudiness.

The scant hair in snthr-1Bao mice is likely caused by a deletion affecting the Plcd1 gene.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

Certain genetic markers can indicate higher or lower risk for systemic lupus erythematosus.

Blocking IL-17a can improve age-related smell loss in mice.

The DiLiCre mouse model is an effective tool for precise genome editing using light.

Mice without the p21 gene can fully regenerate injured ears due to reduced Sdf1 increase and leukocyte recruitment, suggesting new ways to induce tissue regeneration in mammals.

TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.