research Transcriptional profiling in alopecia areata defines immune and cell cycle control related genes within disease-specific signatures
The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.
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research Hair follicle immune privilege in autoimmune and immune-mediated alopecias: paths toward reestablishing immune tolerance
Different types of alopecia cause hair loss due to immune system issues, with some allowing regrowth and others causing permanent loss.
research Macrophages as central mediators of sympathetic neuro-immune interplay in autoimmunity
Restoring nerve-macrophage communication may help treat autoimmune diseases.
research Immune modulation of hair follicle regeneration
Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
research Construction of regulatory network for alopecia areata progression and identification of immune monitoring genes based on multiple machine-learning algorithms
Researchers found four genes that could help diagnose severe alopecia areata early.
research The Dynamics of the Skin’s Immune System
The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
research What’s Sex Got to Do With COVID-19? Gender-Based Differences in the Host Immune Response to Coronaviruses
Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.
research Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management
Restoring hair bulb immune privilege is crucial for managing alopecia areata.
research Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia
Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
research Differential proteomics of lesional vs. non-lesional biopsies revealed non-immune mechanisms of alopecia areata
Non-immune factors play a significant role in alopecia areata.
research Implication of Human Bacterial Gut Microbiota on Immune-Mediated and Autoimmune Dermatological Diseases and Their Comorbidities: A Narrative Review
An imbalance in gut bacteria is linked to skin immune diseases and may affect their outcomes and related health issues.
research Humanized CXCL12 antibody delays onset and modulates immune response in alopecia areata mice: insights from single-cell RNA sequencing
A humanized CXCL12 antibody may delay and treat alopecia areata by altering the immune response.
research Early prediction of alopecia areata using machine learning modeling of neuro stress immune signatures from multi datasets
A machine learning model can predict alopecia areata early using specific gene markers.
research Engineering immune-competent hair follicle microphysiological systems: from organoid assembly to dynamic immune modelling
Hair follicle systems are being engineered to better mimic natural hair follicles for studying hair disorders and testing treatments.
research Melan-A Positive cells significantly expressed in immune-targeted follicles of Alopecia Areata
Melanocytes may trigger the immune response in alopecia areata, affecting hair regrowth.
research Cutaneous signals of immune system disease
Skin issues can indicate immune system problems.
research The hair follicle as a neuro-immuno-endocrine organ: Implications in hair disorders and regenerative therapies
Understanding hair follicle signaling can improve hair disorder treatments.
research The Immune Functions of Keratinocytes in Skin Wound Healing
Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
research Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata
Early intervention with JAK inhibitors may prevent alopecia areata progression.
research Identification of Distinct Immune Signatures and Chemokine Networks in Scalp Inflammatory Diseases
Different immune responses cause hair loss in scalp diseases, with unique patterns in scalp psoriasis possibly protecting against hair loss.
research An immune regulatory CCT repeat containing oligodeoxynucleotide capable of causing hair loss in male mice
A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.
research Burden of immune-related skin diseases worldwide, 1991–2021: insights and prediction from the Global Burden of Disease Study
Females are more affected by immune-related skin diseases, needing targeted health interventions.
research Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
research Identifying key components and therapeutic targets of the immune system in hidradenitis suppurativa with an emphasis on neutrophils
The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.
research PINK1 deficiency rewires early immune responses in a mouse model of Parkinson’s disease triggered by intestinal infection
PINK1 is important for controlling gut immune responses linked to early Parkinson's disease.
research Regulation of the innate immune response in rheumatoid arthritis
More research is needed to understand and manage rheumatoid arthritis better.
research Regulatory T cells: master orchestrators of immune tolerance and tissue homeostasis
Regulatory T cells help control the immune system and could lead to new treatments for diseases.
research A Case Study on Exploring Immune Dysregulation in Alopecia Areata - Mechanisms and Treatments Outcomes
Individualized treatment and psychological support improved the patient's quality of life and appearance despite medication side effects.
research Stress, Hair Growth Control, and the Neuro-Endocrine-Immune Connection
Stress may affect hair growth by influencing hair follicle development and could contribute to hair loss.
research Alopecia areata: a comprehensive review of clinical, immunologic, and genetic perspectives
Alopecia Areata is an autoimmune disease causing hair loss, with no cure yet, but research may lead to new treatments.