65 citations
,
February 2017 in “Pflügers Archiv - European Journal of Physiology” Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.
18 citations
,
October 2023 in “Nature Communications” Men with baldness are more prone to skin cancers on the scalp due to sun exposure, not testosterone.
51 citations
,
March 2014 in “Nature Communications” Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.
18 citations
,
September 2006 in “Dermatologic Surgery” Aggressive scalp squamous cell carcinomas have a high death rate and need early, strong treatment.
May 2014 in “Journal of Investigative Dermatology” Scientists developed tools to observe hair regeneration in real time and assess skin health, using glowing mice and light-controlled genes.
September 2006 in “Dermatologic Surgery” Some aggressive scalp cancers are hard to treat and can be deadly, even when removed with specialized surgery.
March 2026 in “Frontiers in Cell and Developmental Biology” Vascular endothelial cells may significantly influence skin stem cells, but more research is needed.
March 2024 in “Research Square” The model helps understand alopecia areata and suggests ways to improve treatment by targeting immune issues.
February 2024 in “Frontiers in physiology” Lymphatic vessels are important for skin repair and could affect skin disease treatments.
January 2024 in “Research Square” The model helps understand alopecia areata and suggests treatment strategies.
191 citations
,
May 2018 in “British journal of dermatology/British journal of dermatology, Supplement” Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.
141 citations
,
August 2017 in “Developmental Dynamics” The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.
110 citations
,
July 2017 in “Immunology” Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
77 citations
,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
64 citations
,
August 2013 in “Mayo Clinic Proceedings” Wound healing insights can improve regenerative medicine.
63 citations
,
March 2016 in “International Journal of Molecular Sciences” Children with atopic dermatitis often have sleep problems due to itching and may benefit from melatonin, which helps with sleep and skin symptoms.
46 citations
,
December 2018 in “Genes & Development” Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
42 citations
,
February 2021 in “Signal Transduction and Targeted Therapy” Hair follicle regeneration possible, more research needed.
39 citations
,
January 2013 in “Journal of Investigative Dermatology” Changing Wnt signaling can lead to more or less hair growth and might help treat hair loss and skin conditions.
23 citations
,
November 2020 in “Central-European Journal of Immunology/Central European Journal of Immunology” Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.
1 citations
,
March 2024 in “Signal transduction and targeted therapy” NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
July 2026 in “npj Regenerative Medicine” Gli2 and Serpinh1 are key for skin wound healing by helping fibroblasts close wounds.
Lack of certain cells causes abnormal nipple development and nursing failure.
November 2023 in “npj regenerative medicine” Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
September 2014 in “Aktuelle Dermatologie” The symposium concluded that environmental factors significantly contribute to skin aging.
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
April 2017 in “Journal of Investigative Dermatology” A virus protein can activate a pathway that may lead to abnormal hair follicle development.
January 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Mothers have more hair proteins than their children, with age-related differences in protein patterns, and some proteins in hair could indicate early childhood development.
291 citations
,
January 2014 in “The Scientific World Journal” Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.
188 citations
,
March 2018 in “Frontiers in Immunology” Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.