May 2024 in “JAMA Dermatology” Oral contraceptive use may increase the risk of frontal fibrosing alopecia in women with a specific CYP1B1 gene variant.
April 2017 in “Journal of Investigative Dermatology” SM04755 may be an effective topical treatment for psoriasis.
41 citations
,
September 2012 in “Cellular and Molecular Life Sciences” MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
4 citations
,
September 2019 in “Biomedical Papers/Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc Czech Republic” CD2 might be a new treatment target for patchy alopecia areata.
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.
328 citations
,
November 2020 in “Nature Materials” Hydrogel scaffolds can help wounds heal better and grow hair.
2 citations
,
March 2021 in “Molecular Immunology” Dermal macrophages might help regrow hair.
May 2026 in “Frontiers in Cell and Developmental Biology” Hair follicle organoids can help study hair biology and disorders but need improvements for wider use.
April 2026 in “Cellular and Molecular Immunology” SPT6 prevents excessive skin inflammation by blocking a feedback loop.
July 2025 in “International Journal of Molecular Sciences” Blocking CXCL12 can reverse hair loss and fibrosis in androgenetic alopecia.
November 2022 in “Annals of Translational Medicine” Immune activities and specific genes are important in male pattern baldness.
28 citations
,
April 2023 in “Stem cell research & therapy” Tiny vesicles from stem cells could be a new treatment for healing wounds.
18 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
3 citations
,
November 2023 in “Frontiers in cell and developmental biology” Melanocytes are important for skin and hair color and protect the skin from UV damage.
June 2023 in “Research Square (Research Square)” Hair loss in male pattern baldness is linked to changes in immune cell behavior around hair follicles.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” miR-486 may help prevent hair loss in alopecia areata.
146 citations
,
February 2012 in “Journal of Clinical Investigation” Blocking Hedgehog signaling offers new treatment options for advanced basal cell carcinoma.
125 citations
,
September 2001 in “The FASEB Journal” Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.
13 citations
,
January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
27 citations
,
July 2017 in “Scientific Reports” N-WASP is essential for healthy skin and preventing inflammation.
1 citations
,
July 2019 in “Clinical Rheumatology” Leflunomide is more likely to help treat alopecia areata than cause it.
9 citations
,
July 2022 in “EMBO molecular medicine” Blocking certain immune signals can reduce skin damage from radiation therapy.
8 citations
,
October 2021 in “Stem Cell Research & Therapy” Mesenchymal stem cells may effectively treat and prevent allergic skin conditions.
5 citations
,
January 2025 in “Burns & Trauma” Machine learning and single-cell analysis improve understanding and treatment of wound healing.
June 2025 in “International Journal of Molecular Sciences” Targeting EMT and fibrotic remodeling may help treat androgenetic alopecia.
March 2024 in “Research Square” The model helps understand alopecia areata and suggests ways to improve treatment by targeting immune issues.
January 2024 in “Research Square” The model helps understand alopecia areata and suggests treatment strategies.
January 2024 in “Applied Mathematics and Nonlinear Sciences” The model helps understand alopecia areata and suggests better treatment strategies.
163 citations
,
April 2019 in “Nature Communications” Mechanical stretching of the skin can promote hair growth by activating certain immune cells.
127 citations
,
January 2015 in “Journal of Biological Rhythms” The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.