June 2023 in “Research Square (Research Square)” Different immune responses cause hair loss in scalp diseases, with unique patterns in scalp psoriasis possibly protecting against hair loss.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain immune cells, when activated by specific signals, can encourage hair growth.
64 citations
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August 2014 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking EGFR can lead to hair loss due to inflammation and stem cell damage.
139 citations
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August 2018 in “Development” The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.
16 citations
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October 2018 in “Experimental Dermatology” Mesenchymal stem cell therapy may help treat alopecia areata by promoting hair growth and reducing inflammation.
15 citations
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June 2015 in “F1000Research” Psoriasis may be chronic because it lacks certain immune system controls that prevent overreaction.
12 citations
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March 2021 in “JAAD Case Reports” Nail changes from immunotherapy can be managed without stopping cancer treatment.
8 citations
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January 2022 in “Journal of Experimental Orthopaedics” It's unclear if cell-based therapies from lipoaspirate devices improve clinical outcomes due to inconsistent data.
6 citations
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May 2013 in “The Journal of Dermatology” Autoimmune reactions may cause both alopecia areata and HAM.
4 citations
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June 2024 in “British Journal of Dermatology” EGFRi/MEKi treatments cause hair follicles to lose some immune protection, leading to inflammation.
2 citations
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February 2025 Merkel cell polyomavirus can infect and persist in skin cells, evading the immune system, but certain treatments can control it.
1 citations
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April 2025 in “Journal of Feline Medicine and Surgery” Early diagnosis and treatment by vets are crucial for managing rare but severe feline skin disorders.
1 citations
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March 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Biodegradable scaffolds help regenerate wounds and hair by activating the immune system.
December 2025 in “Journal of Investigative Dermatology” Immune system issues may contribute to female pattern hair loss.
August 2025 in “International Journal of Cancer” Childhood and adult height, and early immune-related hospitalizations increase testicular cancer risk, while baldness, larger families, and sports reduce it.
April 2021 in “Journal of Investigative Dermatology” Arg1+ macrophages may play a role in causing alopecia areata.
February 2026 in “Stem Cell Research & Therapy” Stem cell therapies show promise for hair regrowth in alopecia areata but need more research for safety and effectiveness.
June 2023 in “Research Square (Research Square)” Hair loss in male pattern baldness is linked to changes in immune cell behavior around hair follicles.
13 citations
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May 2023 in “Journal of Dermatological Science” Reduced SIRT1 in hair cells may cause alopecia areata by triggering immune responses.
76 citations
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January 2017 in “World Journal of Stem Cells” Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.
59 citations
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March 2020 in “Journal of Biomedical Science” Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
57 citations
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May 1980 in “International Journal of Dermatology” Langerhans cells are crucial for skin immunity and allergic reactions.
20 citations
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December 2010 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Decreased CD200 in hair follicles may cause immune issues in some alopecia areata cases.
4 citations
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January 2024 in “Allergy” Everyone has an immune response to PPD, but reactions differ, causing tolerance, mild inflammation, or allergy.
2 citations
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December 2022 in “The Journal of Dermatology” Patients with hidradenitis suppurativa have higher levels of cell-free DNA in their blood.
May 2023 in “Frontiers in Immunology” Treg cell-based therapies might help treat hair loss from alopecia areata, but more research is needed to confirm safety and effectiveness.
January 2022 in “Biocell” Mesenchymal stem cells and their secretions might help treat chronic skin inflammation in atopic dermatitis.
December 2012 in “Journal of dermatological science” Langerhans cells and melanocytes migrate to the skin and hair follicles during early human development.
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.