15 citations
,
April 2017 in “Cell Stem Cell” Some brain cancer cells avoid immune system detection, and certain treatments could target this to slow their growth; also, certain fat cell precursors help regenerate hair and skin after injury.
45 citations
,
April 2019 in “International Immunology” The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.
January 2026 in “Immunity & Inflammation” Autoimmune skin diseases result from genetic and environmental factors disrupting immune checkpoints.
18 citations
,
March 2024 in “Frontiers in Pharmacology” Natural plant products like Proanthocyanidins and curcumin may help treat ischemic stroke by reducing inflammation.
16 citations
,
September 2020 in “British journal of dermatology/British journal of dermatology, Supplement” The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.
November 2024 in “Journal of Investigative Dermatology” Targeting PTEN can improve healing in venous leg ulcers.
IL-1 signaling is crucial for hair follicle stem cell growth and wound healing.
20 citations
,
December 2020 in “Frontiers in Immunology” The immune processes causing VKH and vitiligo are similar in dogs and humans.
1 citations
,
January 2025 in “Advances in Wound Care” Dermal sheath cells help heal wounds by showing both skin and connective tissue traits.
September 2019 in “Encyclopedia of Life Sciences” Wound healing involves complex signaling that stops bleeding, reduces damage, and repairs skin, sometimes without scarring.
85 citations
,
December 2017 in “Developmental Biology” Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
May 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” KAP-depleted hair causes less immune response and is more biocompatible for implants.
October 2022 in “Frontiers in Cell and Developmental Biology” Aging skin is affected by inflammation, reduced stem cell function, and slower wound healing.
7 citations
,
November 2020 in “Experimental Dermatology” Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
Selenium is essential for health, but too little or too much can cause serious health problems.
5 citations
,
October 2024 in “Molecules and Cells” Epidermal stem cells work with the skin's environment to heal wounds effectively.
April 2026 in “Frontiers in Cell and Developmental Biology” GPCRs are vital for wound healing by affecting cell growth and immune response.
1425 citations
,
September 2020 in “Open Biology” Better understanding of wound healing is needed to develop effective treatments for chronic wounds.
2 citations
,
September 2025 in “International Journal of Nanomedicine” Extracellular vesicles can help treat skin issues like wounds, hair loss, aging, and inflammation.
November 2025 in “Frontiers in Immunology” Immune cells are crucial for normal skin development and their dysfunction can cause skin disorders.
February 2024 in “Frontiers in physiology” Lymphatic vessels are important for skin repair and could affect skin disease treatments.
February 2021 in “Journal of Investigative Dermatology” Hair loss in male pattern baldness is linked to changes in specific genes and proteins that affect hair growth and scalp health.
January 2026 in “Inflammation and Regeneration” Two-photon microscopy improves skin imaging but faces safety and cost challenges for clinical use.
1 citations
,
March 2024 in “Signal transduction and targeted therapy” NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
276 citations
,
April 2003 in “Molecular endocrinology” Vitamin D is important for bones, hair, blood pressure, and breast development.
188 citations
,
March 2018 in “Frontiers in Immunology” Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.
137 citations
,
January 2006 in “Frontiers in bioscience” CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
119 citations
,
January 2012 in “Nutrition & Metabolism” Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.
113 citations
,
June 2019 in “F1000Research” Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
80 citations
,
April 2018 in “Trends in Molecular Medicine” Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.