research Unraveling the ECM-Immune Cell Crosstalk in Skin Diseases
Abnormal ECM and immune cell interactions can cause skin diseases.
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research The interplay of oxidative stress and immune dysfunction in Hashimoto’s thyroiditis and polycystic ovary syndrome: a comprehensive review
Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.
research Sparse haplotype-based fine-scale local ancestry inference at scale reveals recent selection on immune responses
Recent selection on immune response genes was identified across seven ethnicities.
research 1391 Immune cells may have a role in hair loss process caused by TRPV3 gain-of-function mutation
Immune cells might contribute to hair loss caused by a specific mutation.
research Immunopharmacological potential of Arctium lappa L. in immune-mediated skin diseases: A critical review of experimental and clinical evidence
Arctium lappa L. might help treat immune-related skin diseases, but more research is needed.
research Integumentary System
The skin protects the body, helps heal wounds, stores energy, and supports health.
research 259 Immunohistochemical insight into the association between the collapse of immune privilege in the sweat gland and syringotropic immune cell infiltrates in collagen diseases
The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.
research Activating an adaptive immune response from a hydrogel scaffold imparts regenerative wound healing
A special gel scaffold was made that speeds up wound healing and skin regeneration, even though it breaks down faster than expected.
research Regulation of the innate immune response in rheumatoid arthritis
More research is needed to understand and manage rheumatoid arthritis better.
research Current and prospective strategies for advancing the targeted delivery of CRISPR/Cas system via extracellular vesicles
Engineered extracellular vesicles could improve CRISPR/Cas delivery, making gene editing safer and more effective.
research Role of the SOX family in cancer immune evasion: Emerging player and promising therapeutic opportunities
Targeting SOX proteins may improve cancer treatment by restoring immune function.
research 757 Wound healing in aged skin exhibits systems-level alterations in cellular composition and cell-cell communication
Aged skin heals slower due to more inflammation and disrupted cell communication.
research Microbial allies in skin trauma recovery: from immune modulation to engineered probiotic therapeutics
Engineered probiotics can help heal wounds faster, especially in diabetic foot ulcers.
research Stress, Hair Growth Control, and the Neuro-Endocrine-Immune Connection
Stress may affect hair growth by influencing hair follicle development and could contribute to hair loss.
research Advances in nanomaterial-mediated CRISPR/Cas delivery: from lipid nanoparticles to vesicle-derived systems
Ionizable lipid nanoparticles are the best for delivering gene-editing therapies.
research Proinflammatory cytokines regulate epidermal stem cells in wound epithelialization
Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
research Association of psoriasis and psoriatic arthritis with human leukocyte antigen and killer cell immunoglobulin–like receptor gene frequency: A multiethnic population study
Certain immune system genes are linked to a higher risk of psoriasis and psoriatic arthritis, while others may offer protection.
research Bioadhesive Polydopamine-Vitamin A Derivative Hydrogels Reprogram the Wound Microenvironment for Scarless Wound Healing and Hair Follicle Regeneration
The hydrogel helps wounds heal without scars and promotes new hair growth.
research Cutaneous Neuroimmune Interactions in Peripheral Neuropathic Pain States
New therapies targeting skin neuroimmune interactions could treat neuropathic pain.
research Biological therapy in the treatment of melanoma
Biological therapy boosts the immune system to effectively fight melanoma.
research The coenzyme A precursor pantethine enhances antitumor immunity in sarcoma
Pantethine may boost the immune system's ability to fight sarcoma.
research Referee report. For: Case Report: Tuberculosis lymphadenitis with systemic lupus erythematosus in a young woman: a case report [version 2; peer review: 2 approved, 1 not approved]
People with weakened immune systems, like those with SLE, are at higher risk for TB.
research Nail Involvement inAutoimmune Bullous Disorders
The nail immune system is similar to hair but different from skin, with fewer immune markers.
research Cytostatics and immunosuppressive drugs
Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.
research Zinc‐Coordinated Trienzyme Nanogel Cascade Therapy for Accelerated Post‐Pancreatectomy Cutaneous Wound Healing
The zinc-coordinated nanogel therapy speeds up wound healing after pancreas surgery by balancing metabolism and fighting bacteria.
research Stress exposure modulates peptidergic innervation and degranulates mast cells in murine skin
Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.
research The autoimmune basis of alopecia areata: A comprehensive review
Alopecia areata is caused by the immune system attacking hair follicles.
research Learning from nudity: lessons from the nude phenotype
The Foxn1 gene mutation causes hairlessness and immune system issues, and understanding it could lead to hair growth disorder treatments.
research Clinical perspectives on the age-related increase of immunosuppressive activity
Aging and chronic inflammation weaken the immune system, increasing cancer and infection risks.
research A kindred with mutant IKAROS and autoimmunity
A mutation in the IKZF1 gene causes immune system overactivity, linked to autoimmune diseases like lupus.