16 citations
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March 2017 in “Oncotarget” SOCS3 treatment can prevent hair loss by stopping harmful immune responses.
8 citations
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July 2020 in “Clinical, cosmetic and investigational dermatology” Excessive sun protection might cause frontal fibrosing alopecia by disrupting skin immune balance.
August 2021 in “BMJ Case Reports” A woman with lupus had blood cell destruction, treated successfully with medication.
54 citations
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December 2011 in “American Journal Of Pathology” A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.
290 citations
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December 2017 in “Journal of The American Academy of Dermatology” Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.
2 citations
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June 2022 in “Journal of cosmetic dermatology” Dupilumab can help hair regrowth but may also trigger alopecia areata.
January 2013 in “Open journal of gastroenterology” Ulcerative colitis can cause skin issues due to immune system problems.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
2 citations
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July 2024 in “Skin Research and Technology” Copper may protect against alopecia areata, while certain inflammatory markers increase risk.
November 2025 in “Scholarly Commons (Embry–Riddle Aeronautical University)” Urban air pollution worsens hair loss in alopecia areata by increasing immune response.
March 2026 in “Frontiers in Medicine” Different types of alopecia cause hair loss due to immune system issues, with some allowing regrowth and others causing permanent loss.
150 citations
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October 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
27 citations
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January 2015 in “Current problems in dermatology” The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.
23 citations
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October 2018 in “Australasian Journal of Dermatology” The current understanding of frontal fibrosing alopecia involves immune, genetic, hormonal factors, and possibly environmental triggers, but more research is needed for effective treatments.
71 citations
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October 2013 in “Experimental Dermatology” Vitiligo and alopecia areata may have similar causes despite their differences.
5 citations
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October 2012 in “Veterinary Pathology” A Doberman Pinscher had a rare form of autoimmune disease causing hair loss and other severe symptoms.
1 citations
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January 2022 in “The Keio Journal of Medicine” Hair follicles regulate immune cells in the skin, and disrupting certain pathways can lead to skin issues and infections.
34 citations
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June 2020 in “British journal of dermatology/British journal of dermatology, Supplement” Frontal fibrosing alopecia is linked to increased immune system activity and reduced stem cells, suggesting early treatment targeting this pathway might prevent hair follicle damage.
51 citations
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December 2017 in “Skin Appendage Disorders” Stress may trigger hair loss by affecting immune protection in hair follicles.
35 citations
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July 2008 in “Dermatologic therapy” Cicatricial alopecia may be caused by immune attacks on hair follicles, gland issues, or stem cell damage.
717 citations
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June 2010 in “Nature” Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.
November 2025 in “Advanced Healthcare Materials” Bioprinting is improving skin models for better testing of skin diseases without using animals.
9 citations
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June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
1 citations
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January 2025 in “Genes & Diseases” Understanding T cells and signaling pathways can lead to better treatments for hair loss.
114 citations
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August 2002 in “Journal of Investigative Dermatology” Alopecia areata is caused by an immune response, and targeting immune cells might help treat it.
21 citations
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January 2024 in “Science Immunology” Regulatory T cells protect hair follicle stem cells by maintaining immune privilege in the skin.
January 2023 in “International Journal of Zoology and Animal Biology” Canine hypothyroidism can be linked to diabetes, requiring thorough testing for proper diagnosis.
10 citations
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March 2016 in “Journal of The American Academy of Dermatology” Finasteride's effectiveness for frontal fibrosing alopecia is uncertain.
June 2011 in “International Journal of Dermatology” A man's red tattoo caused a skin reaction and hair loss in his beard, which improved after treatment.
2 citations
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November 2025 in “Pharmaceutics” Cell-mediated drug delivery systems improve skin disease treatment by using living cells for precise, prolonged, and less toxic therapy.