research MOLECULAR AND CELLULAR BASIS OF EXOGEN AND ANAGEN INDUCTION
Hair growth and shedding involve specific cell changes and gene roles.
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180-210 / 1000+ resultsresearch Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts
Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.
research Case Report: A novel KRT74 variant in an eight-year-old boy with alopecia totalis successfully treated with baricitinib
Baricitinib successfully regrew hair in an 8-year-old boy with alopecia totalis linked to a KRT74 gene variant.
research Evolution of hard proteins in the sauropsid integument in relation to the cornification of skin derivatives in amniotes
Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
research Sustained Exosome‐Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and MiRNAs, and Sustained Release Formulation
Hydrogel with M2-derived exosomes improves wound healing by slowly releasing exosomes that help reduce inflammation and promote tissue repair.
research Red Dots in a Net-Like Pattern on the Upper Chest: A Novel Clinical Observation in Frontal Fibrosing Alopecia and Fibrosing Alopecia in Pattern Distribution
Red dots on the upper chest may be an early sign of certain types of hair loss.
research Phenotyping mice with skin, hair, or nail abnormalities: A systematic approach and methodologies from simple to complex
Understanding genetic variations in mice is crucial for studying skin, hair, or nail abnormalities.
research Fish Acellular Dermal Matrix Promotes Repair of Full‐Thickness Skin Defects in Mice and Bama Pigs
Tilapia skin matrix effectively aids skin wound healing and is a promising option for clinical use.
research Does Complement Have a Role in the Pathogenesis of Alopecia Areata?
The complement system might be involved in the development of alopecia areata and could lead to new treatments.
research Single-cell sequencing combined with spatial transcriptomics reveals the characteristics of follicle-targeted inflammation patterns in primary cicatricial alopecia
Specific immune cells and pathways contribute to hair follicle inflammation and hair loss, suggesting potential treatments for lichen planopilaris.
research Deep Hair Phenomics: Implications in Endocrinology, Development, and Aging
A new tool can analyze hair to detect changes due to hormones, genetics, and aging.
research Application of multi-omics techniques to androgenetic alopecia: Current status and perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
research Development of Hair Keratin Protein to Accelerate Oral Mucosal Regeneration
Hair keratin protein might help heal mouth wounds faster.
research Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis
Sensory neuron remodeling and Merkel-cell changes happen independently during skin maintenance.
research SnapshotDx Quiz: May 2020
BIVV009 is a safe treatment for bullous pemphigoid that reduces C3 deposition without harmful side effects.
research Modeling animal genomics in mice: An authentic approach for the functional interrogation of evolutionarily and agriculturally critical variants
Mouse models are essential for studying and improving genetic traits in agriculture.
research Mammalian target of rapamycin complex 1 (mTORC 1) may modulate the timing of anagen entry in mouse hair follicles
A protein complex called mTORC1 likely affects when hair growth starts in mice.
research Two Cases of Linear Alopecia on the Occipital Scalp
Two rare bald spots on the back of the scalp were found to be lupus, not alopecia areata.
research Autofluorescence in the Stem Cell Region of the Hair Follicle Bulge
Autofluorescence in hair follicle stem cells can interfere with studies but may help isolate these cells.
research Culture and characterization of rat hair follicle stem cells
Rat hair follicle stem cells can be successfully cultured and may be useful for creating tissue-engineered hair, vessels, and skin.
research The composition of cell‐based therapies obtained from point‐of‐care devices/systems which mechanically dissociate lipoaspirate: a scoping review of the literature
It's unclear if cell-based therapies from lipoaspirate devices improve clinical outcomes due to inconsistent data.
research Disorders of hair
The document concludes that hair analysis is not good for assessing nutrition but can detect long-term heavy metal exposure.
research Disturbance of Immune Microenvironment in Androgenetic Alopecia through Spatial Transcriptomics
Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.
research Dermal PapillaCell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1
Exosomes from skin cells can boost hair growth by stimulating a gene called LEF1.
research Adipose transcriptome in the scalp of androgenetic alopecia
The scalp fat tissue of men with hair loss shows changes in gene activity that may contribute to their condition.
research Quantitative Single-Cell Approaches to Stem Cell Research
New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.
research Clinical and molecular genetic studies in hereditary hair loss
Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.
research Hair metal dysregulation in Parkinson’s disease: Implications for diagnosis and gut-brain axis involvement
Hair metal analysis may help diagnose Parkinson's disease and suggests gut involvement.
research Time-dependent 53BP1 foci kinetics in X-irradiated human hair follicle dermal papilla cells
53BP1 focus analysis in hair cells can help estimate radiation doses.
research Histopathology of Scarring and Nonscarring Hair Loss
The conclusion is that accurate diagnosis of different types of hair loss requires careful examination of tissue samples and understanding of clinical symptoms.