61 citations
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December 2016 in “The EMBO Journal” The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.
61 citations
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September 2008 in “Stem Cells” Most hair follicle stem cells do not protect their DNA by dividing it unevenly.
59 citations
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May 2017 in “Scientific reports” ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.
58 citations
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February 2016 in “Scientific reports” Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
57 citations
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December 2021 in “Nature Communications” Non-canonical Wnt signaling helps intestinal stem cells move to injury sites for tissue repair.
55 citations
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April 2017 in “Experimental Dermatology” The document describes a way to isolate and grow human hair follicle cells in 3D to help study hair growth.
53 citations
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April 2014 in “Experimental Dermatology” Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.
53 citations
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January 2009 in “Journal of Investigative Dermatology” UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.
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September 1999 in “The journal of cell biology/The Journal of cell biology” K16 can partially replace K14 but causes hair loss and skin issues.
51 citations
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September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
51 citations
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October 2002 in “British Journal of Dermatology” Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.
50 citations
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April 2014 in “Nature Communications” The research identified new skin traits in mice, some linked to human skin conditions.
49 citations
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April 2000 in “Journal of The American Academy of Dermatology” Despite progress in treatment, the exact cause of Alopecia areata is still unknown.
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February 2025 in “Nano-Micro Letters” Microneedles offer a promising, painless way to treat skin diseases but need improvements for better use.
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November 1992 in “International Journal of Dermatology” Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.
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December 2020 in “Journal of the European Academy of Dermatology and Venereology” The document concludes that understanding and treating hair loss requires recognizing its various types and using appropriate diagnostic tools and treatments.
47 citations
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June 2019 in “Nature Communications” Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.
47 citations
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July 2013 in “Pharmacological Reviews” Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
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May 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.
46 citations
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April 2016 in “Journal of Investigative Dermatology” New genes found linked to balding, may help develop future treatments.
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September 2013 in “PLOS ONE” Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.
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December 2001 in “Journal of Endocrinology/Journal of endocrinology” FLRG and follistatin have different roles in wound healing.
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January 1991 in “Journal of Investigative Dermatology” Minoxidil works in liver and outer hair root sheath for hair growth.
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September 2019 in “The EMBO Journal” Lymphatic vessels are essential for hair follicle growth and skin regeneration.
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June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
44 citations
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January 2011 in “Journal of Cutaneous Pathology” The HoVert technique is a simple, cost-effective new method that improves alopecia diagnosis by allowing detailed analysis from a single biopsy.
42 citations
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March 2018 in “PLOS Biology” Autophagy is important for human hair growth and health.
42 citations
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February 2014 in “Stem Cells and Development” Vitamin C helps adipose-derived stem cells grow and may support hair growth.
41 citations
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March 2017 in “PLoS neglected tropical diseases” Isotretinoin shows promise as a treatment for Chagas disease by effectively inhibiting key transporters in the parasite.
40 citations
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March 2019 in “Nature Communications” CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.