research Post COVID-19 Sequelae in Adults: A Review
Post-COVID syndrome causes long-lasting symptoms like fatigue, breathing issues, and anxiety.
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research Evaluating the serum zinc and vitamin D levels in alopecia areata
People with alopecia areata often have lower levels of zinc and vitamin D.
research Traction alopecia
Tight hairstyles can cause temporary or permanent hair loss, with less hair seen under a microscope in later stages.
research Acne Tarda and Male-Pattern Baldness Unmasking Primary Ovarian Insufficiency: A Case and Review
A woman with acne and baldness was found to have a rare ovarian condition but successfully had a child through fertility treatment.
research Skin
Skin problems are common in Lupus patients and can indicate the disease's severity, requiring specific treatments and lifestyle changes.
research Introductory Chapter: Hair Loss
The document explains the causes, types, diagnosis, and treatments of hair loss, and its psychological impact, especially on women.
research Vitiligo: A comprehensive overview
Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.
research Dermatitis cruris pustulosa et atrophicans revisited: our experience with 37 patients in south India
DCPA is a chronic leg infection often related to Staphylococcus aureus, affecting mostly young men in India.
research What is behind the ‘swarm of bees’ in alopecia areata
Alopecia areata is caused by immune system issues, and JAK inhibitors might help treat it.
research Lichen planopilaris is characterized by immune privilege collapse of the hair follicle's epithelial stem cell niche
Lichen planopilaris may be an autoimmune disease causing hair loss due to immune system issues in hair follicles.
research Cytokine profiles associated with persisting symptoms of post-acute sequelae of COVID-19
Certain immune responses may cause ongoing COVID-19 symptoms like fatigue and brain fog.
research 165 Single-cell RNA sequencing analysis unveils highly active yet diminished CD14+CD16- circulating monocytes, independent of alopecia areata severity
This study investigates the role of circulating monocytes in Alopecia Areata (AA) using single-cell RNA sequencing of peripheral blood mononuclear cells from individuals with mild and severe AA, as well as healthy controls. The analysis reveals a significant depletion of highly active CD14+CD16- monocytes in AA patients, regardless of disease severity, compared to healthy controls. Despite their reduced numbers, these monocytes exhibit heightened metabolic activity and diverse immune responses, including enriched pathways for TLR signaling and interferon-gamma-mediated signaling. The study highlights the paradoxical nature of these monocytes, suggesting their pivotal role in systemic inflammation and potential as therapeutic targets in AA pathogenesis.
research Mitochondrial dysfunction in metabolic syndrome and inflammatory skin disease
Mitochondrial dysfunction links metabolic syndrome and inflammatory skin diseases, suggesting targeted therapies and lifestyle changes.
research Melanocortin receptor type 2 (MC2R, ACTH receptor) expression in patients with alopecia areata
Lower MC2R expression may contribute to alopecia areata.
research Antigen presenting cells in the skin of a patient with hair loss and systemic lupus erythematosus.
Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.
research Effective Role of Cytotoxic CD8+ T Cell in Iraqi Alopecia areata Patients
Higher CD8+ T cell levels are linked to Alopecia areata in Iraqi patients.
research Exploring the hair follicle immune privilege state in nonsegmental vitiligo
Hair follicles in nonsegmental vitiligo are better protected from immune attacks than in alopecia areata.
research The Carcinogenesis of the Human Scalp: An Immunometabolic-Centered View
Hair helps prevent scalp skin cancer by supporting immune protection.
research Cutaneous microbial biofilm formation as an underlying cause of red scrotum syndrome
Microbial biofilms may cause red scrotum syndrome.
research Gsdma3 Mutation Causes Bulge Stem Cell Depletion and Alopecia Mediated by Skin Inflammation
A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.
research Hidradenitis Suppurativa as a Potential Subtype of Autoinflammatory Keratinization Disease
Hidradenitis suppurativa might be a type of autoinflammatory skin disease.
research Mycobacterial 65,000 MW heat-shock protein shares a carboxy-terminal epitope with human epidermal cytokeratin 1/2.
A mycobacterial protein shares a similar region with a human skin protein, possibly affecting skin diseases.
research A concomitant diagnosis of COVID‐19 infection and systemic lupus erythematosus complicated by a macrophage activation syndrome: A new case report
COVID-19 may trigger systemic lupus erythematosus, requiring careful diagnosis and treatment.
research Alopecia universalis during treatment with leflunomide and adalimumab - Case report
A patient lost all their hair while on rheumatoid arthritis medication.
research Pathological Mechanisms Involved in Epidermolysis Bullosa Simplex: Current Knowledge and Therapeutic Perspectives
Promising treatments for EBS include anti-inflammatory drugs, antibiotics, creams, mTOR inhibitors, and gene editing, but more trials are needed.
research Exploring the Complexities of Atopic Dermatitis: Pathophysiological Mechanisms and Therapeutic Approaches
Atopic dermatitis needs personalized treatment using various therapies, starting with topical corticosteroids.
research A Case of Frontal Fibrosing Alopecia in a Patient with Primary Biliary Cirrhosis and Polymyalgia Rheumatica
Frontal fibrosing alopecia might be linked to autoimmune diseases.
research Efficacy and Potential Mechanisms of Naringin in Atopic Dermatitis
Naringin may help treat atopic dermatitis by reducing inflammation and improving the skin barrier.
research RETRACTED: Serum lipids may causally affect the occurrence of alopecia areata: A Mendelian randomization study
Higher LDL lipids may increase alopecia areata risk, while higher triglycerides may decrease it.
research Relationship between hair shedding and systemic inflammation in COVID-19 pneumonia
Hair shedding after COVID-19 is more linked to the disease's severity and inflammation rather than hormones, with women at higher risk.