5 citations
,
November 1999 in “Medical Hypotheses” Minoxidil, a common hair loss treatment, might work by counteracting a hormone that reduces hair growth and promotes hair loss.
January 2026 in “Frontiers in Cellular Neuroscience” Neurosteroids like neuro-estrogen and neuro-androgen are crucial for brain function and can improve cognition and protect against aging-related decline.
January 1989 in “Clinical and Experimental Dermatology” The symposium concluded that hair growth involves complex processes, including the hair follicle life cycle, the role of the dermal papilla, hair strength, pigmentation, and the impact of diseases and treatments like minoxidil on hair and skin.
5 citations
,
June 2015 in “Veterinary dermatology” A dog with complete hair loss regrew most hair after treatment, with no relapse after stopping treatment.
115 citations
,
October 2003 in “Journal of Neuroscience” Aβ afferents do not sprout into the superficial spinal cord layers after nerve injury.
30 citations
,
July 2018 in “Scientific Reports” Blocking certain fat production can reverse skin inflammation and hair loss.
30 citations
,
September 2003 in “Experimental Dermatology” Minoxidil helps prevent stress-caused hair loss in mice.
22 citations
,
October 2019 in “Cerebral cortex” Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
January 2022 in “Dermatology Review” Higher IL-31 levels are linked to worse itching in chronic kidney disease patients.
506 citations
,
January 2012 in “Molecular and Cellular Endocrinology” Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
256 citations
,
October 2013 in “Nature Communications” Bioengineered lacrimal glands can restore tear production and protect eyes.
168 citations
,
August 2000 in “American Journal of Pathology” Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.
134 citations
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December 2018 in “Dermatology and Therapy” Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.
131 citations
,
August 2004 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.
109 citations
,
December 2003 in “American Journal of Pathology” Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.
81 citations
,
January 2003 in “The FASEB Journal” Follistatin helps hair growth and cycling, while activin prevents it.
68 citations
,
July 2011 in “Journal of Biochemistry/The journal of biochemistry” New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.
68 citations
,
September 1990 in “Biochemical Pharmacology” Minoxidil activates hair growth by being sulfated by P-PST in the human liver.
64 citations
,
June 1992 in “International Journal of Dermatology” Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.
49 citations
,
November 2019 in “Egyptian Journal of Medical Human Genetics” Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.
46 citations
,
January 1991 in “Journal of Investigative Dermatology” Minoxidil works in liver and outer hair root sheath for hair growth.
35 citations
,
January 2002 in “Scandinavian Journal of Urology and Nephrology” Finasteride reduces prostate bleeding by affecting blood vessel growth.
32 citations
,
February 2016 in “The American journal of dermatopathology/American journal of dermatopathology” Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.
27 citations
,
May 2015 in “Neuropharmacology” Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.
22 citations
,
August 1999 in “Experimental Dermatology” Certain drugs can cause early hair growth in mice by affecting the nerves.
18 citations
,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
12 citations
,
February 2014 in “PLoS ONE” Topical rapamycin may effectively treat fibrous papules on the face.
11 citations
,
September 2021 in “Journal of molecular endocrinology” ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
11 citations
,
April 2016 in “The American Journal of Dermatopathology” Special and immunohistochemical stains are not routinely needed for diagnosing hair disorders.
11 citations
,
July 2015 in “Gene” DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.