research Quality of life in cutaneous lupus erythematosus
Patients with cutaneous lupus erythematosus have a severely impaired quality of life, especially emotionally.
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300-330 / 1000+ resultsresearch Evaluation of Keratinocyte Proliferation and Differentiation in Vitamin D Receptor Knockout Mice
Alopecia in VDR knockout mice is due to impaired hair cycle initiation, not keratinocyte issues.
research Cellular Activity in the Dermis Surrounding the Hair Bulb in Alopecia Areata
Hair growth in alopecia areata is hindered due to impaired cell activity in the surrounding tissue.
research The overexpression of R-spondin 3 affects hair morphogenesis and hair development along with the formation and maturation of the hair follicle stem cells
Overexpression of R-spondin 3 leads to sparse hair and impaired hair regeneration.
research 319 Mechanisms of cell death regulation in hair regeneration
Blocking cell death in hair follicles can lead to impaired hair growth.
research Investigating the mechanisms underlying age-related dysfunctions in skin and hair follicle regeneration
Senescence and genomic instability in fibroblasts contribute to hair loss and impaired skin regeneration with age.
research Obesity and peri-implantation endometrium
Obesity negatively affects the endometrium, leading to higher miscarriage risk and impaired cell function.
research Urinary symptoms in patients with androgenetic alopecia
Lower nitric oxide and higher fibrinogen found in hirsute women; impaired sexual function in 22.6% of hair loss patients, linked to psoriasis severity.
research A Neutralizing Prolactin Receptor Antibody Whose In Vivo Application Mimics the Phenotype of Female Prolactin Receptor-Deficient Mice
The antibody 005-C04 blocks prolactin receptors, causing reversible infertility, impaired lactation, and hair regrowth in female mice.
research LB1256 TRIV-509, a dual inhibitor of KLK5 and KLK7, rapidly improves barrier integrity and markers of epidermal differentiation in atopic dermatitis skin explants
TRIV-509 quickly improves skin barrier and cell health in atopic dermatitis.
research A systematic review of patient‐reported outcomes in patients with cutaneous lupus erythematosus
Cutaneous lupus erythematosus greatly reduces patients' quality of life.
research Pregnancy's lasting imprint: Late pregnancy allopregnanolone alters rat fear recall and medial prefrontal cortex activity
Pregnancy affects fear memory and brain activity in female rats.
research Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation
Msx2 deficiency in mice leads to bone growth and organ development problems.
research Quality of Life in Alopecia Areata: A Sample of Tunisian Patients
Alopecia areata significantly worsens quality of life, suggesting a need for mental health support.
research Androgens Protect against Apolipoprotein E4-Induced Cognitive Deficits
Androgens can help prevent memory problems caused by apoE4.
research Elevated Circulation Levels of an Antiangiogenic SERPIN in Patients with Diabetic Microvascular Complications Impair Wound Healing through Suppression of Wnt Signaling
High kallistatin levels in diabetics worsen wound healing by blocking important cell signals.
research The Function of LPR1 is Controlled by an Element in the Promoter and is Independent of SUMO E3 Ligase SIZ1 in Response to Low Pi Stress in Arabidopsis thaliana
LPR1 regulates root growth under low phosphate stress independently of SIZ1 in Arabidopsis thaliana.
research Hypertension and Reproduction
Reproductive factors can increase hypertension risk and affect cardiovascular health.
research DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization
Vitamin D receptor is important for regulating hair growth and wound healing in mice.
research Psychosocial impact of alopecia areata in paediatric and adolescent populations: A systematic review
Alopecia areata negatively affects the self-esteem and quality of life of children and teens.
research Seborrheic Dermatitis Revisited: Pathophysiology, Diagnosis, and Emerging Therapies—A Narrative Review
New treatments for seborrheic dermatitis show promise for difficult cases.
research Epidermolysis Bullosa Simplex Keratinocytes Show Disturbed Mitochondrial Positioning and Activity
Skin cells from people with Epidermolysis Bullosa Simplex have abnormally placed and less active mitochondria.
research Impairment of Hair-Inducing Capacity of Three-Dimensionally Cultured Human Dermal Papilla Cells by the Ablation of STAT5
STAT5 is crucial for hair growth in 3D cultured human dermal papilla cells.
research Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration
Hair regeneration needs dynamic cell behavior and mesenchyme presence for stem cell activation.
research Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle
Inhibiting Bmp signaling disrupts hair growth and differentiation.
research Mitochondrial Reactive Oxygen Species Promote Epidermal Differentiation and Hair Follicle Development
Mitochondrial reactive oxygen species are essential for skin and hair development.
research Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization
Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.
research Exploring the role of stem cells in cutaneous wound healing
Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.
research Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients
Schizophrenia patients' stem cells show abnormal neuron development and mitochondrial issues.
research p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis
p63 controls Satb1 to help skin develop properly.