January 2012 in “International Society of Hair Restoration Surgery” Finasteride is effective for hair loss but has controversial side effects.
November 2022 in “Hair transplant forum international” Finasteride does not cause sexual dysfunction in men with hair loss.
February 2023 in “Sexual Medicine Reviews” Finasteride impairs sperm quality and fertility in rats, even after stopping treatment.
20 citations
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April 2012 in “Fertility and Sterility” Finasteride causes lasting fertility decrease in rats.
1 citations
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June 2017 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride use may cause sexual dysfunction; more research needed.
September 2019 in “Reactions Weekly” Man experienced post-finasteride syndrome symptoms after using finasteride and dutasteride for hair loss.
The document suggests that drugs for prostate issues might cause lasting sexual, mental, and physical health problems due to blood vessel damage in the penis.
May 2023 in “The Journal of Sexual Medicine” Men with self-diagnosed PFS-related ED have normal erectile hemodynamics.
32 citations
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March 2019 in “Climacteric” Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.
September 2003 in “Reactions Weekly”
October 2024 in “Journal of the Endocrine Society” Post-finasteride syndrome can cause lasting sexual, physical, and mental health issues with limited treatment options.
17 citations
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December 2018 in “The World Journal of Men s Health” Long-term use of dutasteride can cause permanent erectile dysfunction in rats.
February 2024 in “Urology” Certain medications, especially Paroxetine, Tamsulosin, and Finasteride, are linked to ejaculatory disorders.
18 citations
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March 2019 in “Journal of The European Academy of Dermatology and Venereology” Finasteride use doesn't cause sexual dysfunction in men with hair loss.
January 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Finasteride may be a promising treatment for recurrent priapism in sickle cell anemia.
May 2023 in “The Journal of Sexual Medicine” Flibanserin may help improve sexual symptoms in various conditions beyond its approved use.
March 2023 in “The Journal of Urology” Men with better urinary symptoms have a lower risk of death.
29 citations
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July 2012 in “The Journal of Sexual Medicine” Rats had lasting erectile problems after stopping a certain medication.
April 2017 in “Actas urológicas españolas” 5-alpha reductase inhibitors increase the risk of sexual dysfunction in patients treating enlarged prostate but not in those treating hair loss.
June 2026 in “Frontiers in Medicine” This systematic review examines the sexual dysfunction associated with 5α-reductase inhibitors (5-ARIs) used for treating androgenetic alopecia (AGA). Analyzing 41 studies, it finds that sexual adverse events, such as decreased libido and erectile dysfunction, occur in 1.9–6.7% of men taking oral finasteride and 4.1–12.0% for dutasteride, with lower rates for topical finasteride. These effects are generally mild, reversible, and not consistently reported in women. Clinicians should inform patients about these potential side effects, emphasizing their infrequency and reversibility, while advocating for shared decision-making and further research to better understand individual susceptibility and long-term risks.
March 2013 in “Reactions Weekly” A man's fertility improved after he stopped taking finasteride but worsened again when he restarted the medication.
2 citations
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March 2021 in “Reproduction” Finasteride may affect male fertility by interfering with specific sperm signaling.
June 2014 in “Reactions Weekly” Finasteride can cause muscle weakness and eye movement issues, even at low doses.
40 citations
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April 2018 in “Endocrine” PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.
125 citations
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January 1999 in “Drugs” Finasteride effectively treats baldness but may cause sexual side effects.
12 citations
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March 2023 in “The FASEB Journal” Platelet-rich plasma can improve erectile function in older individuals by reducing prostate enlargement.
8 citations
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April 2004 in “The Journal of Urology” Doxazosin and finasteride negatively affect sexual function in men with BPH.
30 citations
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January 2020 in “Fertility and Sterility” Finasteride can cause serious side effects in some men, needing more research for treatment.
Finasteride and testosterone are the drugs most linked to male infertility, but many other potential drugs may be under-reported.