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research The influence of biotin on viability, pyruvate carboxylase activity and the response to malate concentration in vitro</i> by isolated secondary hair follicles of the Angora goat

January 1999 in “Proceedings of the British Society of Animal Science”

Biotin deficiency may harm hair follicle health and growth in Angora goats.

research 1494 Dual effects of HA-iMSC-exosomes in human follicle dermal papilla cells (HFDPC) on androgenic alopecia in vitro model
April 2023 in “Journal of Investigative Dermatology”

Exosomes from certain stem cells can fight hair loss by promoting hair growth and maintaining the growth phase of hair.

research Metabolic study of androsta-1,4,6-triene-3,17-dione in horses using liquid chromatography/high resolution mass spectrometry
17 citations , August 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.

research t-Flavanone Improves the Male Pattern of Hair Loss by Enhancing Hair-Anchoring Strength: A Randomized, Double-Blind, Placebo-Controlled Study
7 citations , February 2016 in “Dermatology and therapy”

t-Flavanone helps improve male pattern hair loss by making hair roots stronger.

research The Acne-treatment Potential of Cinnamomum Camphora Chvar. Borneol Essential Oil in Vitro and in Vivo
August 2021 in “Research Square (Research Square)”

Borneol Essential Oil could be a natural and safe acne treatment.

research Development of Provesicular Nanodelivery System of Curcumin as a Safe and Effective Antiviral Agent: Statistical Optimization, In Vitro Characterization, and Antiviral Effectiveness
37 citations , December 2020 in “Molecules”

A new delivery system makes Curcumin more effective and safer against viruses.

research Demethylation of ITGAV accelerates osteogenic differentiation in a blast-induced heterotopic ossification in vitro cell culture model
11 citations , December 2018 in “Bone”

Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.

research Pectin Nanoparticle-Loaded Soft Coral Nephthea sp. Extract as In Situ Gel Enhances Chronic Wound Healing: In Vitro, In Vivo, and In Silico Studies
10 citations , July 2023 in “Pharmaceuticals”

The gel with coral extract and pectin nanoparticles helps heal chronic wounds.

research In Vitro Main Pathways of Steroid Action in Cultured Hair Follicle Cells: Vascular Approach
30 citations , December 1999 in “Journal of Investigative Dermatology Symposium Proceedings”

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

research A novel derivative of doxorubicin, AD198, inhibits canine transitional cell carcinoma and osteosarcoma cells in vitro
12 citations , September 2015 in “Drug Design Development and Therapy”

AD198 is more effective than doxorubicin in stopping certain dog cancer cells.

research In Vitro Performance of Dutasteride-Nanostructured Lipid Carriers Coated with Lauric Acid-Chitosan Oligomer for Dermal Delivery
8 citations , October 2020 in “Pharmaceutics”

Dutasteride-loaded nanoparticles coated with Lauric Acid-Chitosan show promise for treating hair loss due to their controlled release, low toxicity, and potential to stimulate hair growth.

research HaCaT‑conditioned medium supplemented with the small molecule inhibitors SB431542 and CHIR99021 and the growth factor PDGF‑AA prevents the dedifferentiation of dermal papilla cells in vitro</i>
7 citations , March 2021 in “Molecular Medicine Reports”

A mix of specific inhibitors and a growth factor helps keep hair growth cells from losing their properties in the lab.

research Type 2 Cytokine–Dependent Skin Barrier Regulation in Personalized 2-Dimensional and 3-Dimensional Skin Models of Atopic Dermatitis: A Pilot Study
2 citations , August 2024 in “JID Innovations”

AD-derived keratinocytes effectively mimic inflammation in atopic dermatitis.

research Natural Product-Inspired Bis(trifluoromethyl) Phenyl Hydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitors of Human Steroid 5α-Reductase Type-1: Synthesis, In Vitro</i>, and In Silico Studies
August 2025 in “ACS Omega”

New compounds show promise as nonsteroidal treatments for hair loss.

research Skin and hair on-a-chip: in vitro skin models versus ex vivo tissue maintenance with dynamic perfusion
208 citations , January 2013 in “Lab on a Chip”

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

research Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo
68 citations , December 2011 in “Journal of Investigative Dermatology”

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

research A novel control of human keratin expression: cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytesin vitro</i>andin situ
66 citations , February 2013 in “PeerJ”

Activating cannabinoid receptor 1 reduces certain keratin levels, potentially aiding psoriasis treatment.

research Effects of epidermal growth factor, fibroblast growth factor, minoxidil and hydrocortisone on growth kinetics in human hair bulb papilla cells and root sheath fibroblasts cultured in vitro
58 citations , June 1987 in “Archives of Dermatological Research”

EGF and FGF boost hair cell growth, hydrocortisone slows it, and minoxidil doesn't affect it.

research Pitx2, a β-catenin-regulated transcription factor, regulates the differentiation of outer root sheath cells cultured in vitro
51 citations , February 2009 in “Journal of dermatological science”

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

research Endocrine controls of primary adult human stem cell biology: Thyroid hormones stimulate keratin 15 expression, apoptosis, and differentiation in human hair follicle epithelial stem cells in situ and in vitro
42 citations , July 2010 in “European Journal of Cell Biology”

Thyroid hormones affect hair follicle stem cells by promoting differentiation and reducing growth.

research VEGF165 modulates proliferation, adhesion, migration and differentiation of cultured human outer root sheath cells from central hair follicle epithelium through VEGFR-2 activation in vitro
35 citations , October 2013 in “Journal of Dermatological Science”

VEGF165 influences hair follicle cell growth and movement through VEGFR-2 activation.

research Arabidopsis thaliana as a model system for the study of the effect of inoculation by azospirillum brasilense Sp-245 on root hair growth
29 citations , December 1994 in “Soil Biology and Biochemistry”

Inoculating Arabidopsis with Azospirillum brasilense significantly increases root hair length.

research Conditioned medium from primary cytotrophoblasts, primary placenta-derived mesenchymal stem cells, or sub-cultured placental tissue promoted HUVEC angiogenesis in vitro
28 citations , February 2021 in “Stem Cell Research & Therapy”

Placental cell medium boosts blood vessel growth in lab tests.

research Cultured dermal papilla cells of the rat vibrissa follicle. Proliferative activity, adhesion properties and reorganization of the extracellular matrix in vitro
27 citations , December 1997 in “Archives of Dermatological Research”

Rat dermal papilla cells have unique properties and interact differently with their environment compared to other skin cells.

research Hair growth in vitro from histocultured skin
25 citations , August 1992 in “In vitro cellular & developmental biology”

The new system can grow hair in the lab and test hair growth treatments.

research Anticancer effects of metformin on neuroendocrine tumor cells in vitro
22 citations , September 2014 in “Hormones”

Metformin may help treat neuroendocrine tumors.

research Formulation of Chitosan-Coated Brigatinib Nanospanlastics: Optimization, Characterization, Stability Assessment and In-Vitro Cytotoxicity Activity against H-1975 Cell Lines
21 citations , March 2022 in “Pharmaceuticals”

The new Brigatinib nanocarrier is more effective against lung cancer cells than the free drug.

research Effects of dihydrotestosterone on rat dermal papilla cells in vitro
19 citations , April 2015 in “European Journal of Pharmacology”

Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

research ProjectH: a collaborative quantitative study of computer-mediated communication
18 citations , April 1998 in “MIT Press eBooks”

DMG-Na may improve blood flow and help hair growth without side effects.

research Investigation of age-related decline of microfibril-associated glycoprotein-1 in human skin through immunohistochemistry study
15 citations , December 2013 in “Clinical Cosmetic and Investigational Dermatology”

MAGP-1 decreases with age, leading to weaker, sagging skin.

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Research

research The influence of biotin on viability, pyruvate carboxylase activity and the response to malate concentration in vitro</i> by isolated secondary hair follicles of the Angora goat

research 1494 Dual effects of HA-iMSC-exosomes in human follicle dermal papilla cells (HFDPC) on androgenic alopecia in vitro model

research Metabolic study of androsta-1,4,6-triene-3,17-dione in horses using liquid chromatography/high resolution mass spectrometry

research t-Flavanone Improves the Male Pattern of Hair Loss by Enhancing Hair-Anchoring Strength: A Randomized, Double-Blind, Placebo-Controlled Study

research The Acne-treatment Potential of Cinnamomum Camphora Chvar. Borneol Essential Oil in Vitro and in Vivo

research Development of Provesicular Nanodelivery System of Curcumin as a Safe and Effective Antiviral Agent: Statistical Optimization, In Vitro Characterization, and Antiviral Effectiveness

research Demethylation of ITGAV accelerates osteogenic differentiation in a blast-induced heterotopic ossification in vitro cell culture model

research Pectin Nanoparticle-Loaded Soft Coral Nephthea sp. Extract as In Situ Gel Enhances Chronic Wound Healing: In Vitro, In Vivo, and In Silico Studies

research In Vitro Main Pathways of Steroid Action in Cultured Hair Follicle Cells: Vascular Approach

research A novel derivative of doxorubicin, AD198, inhibits canine transitional cell carcinoma and osteosarcoma cells in vitro

research In Vitro Performance of Dutasteride-Nanostructured Lipid Carriers Coated with Lauric Acid-Chitosan Oligomer for Dermal Delivery

research HaCaT‑conditioned medium supplemented with the small molecule inhibitors SB431542 and CHIR99021 and the growth factor PDGF‑AA prevents the dedifferentiation of dermal papilla cells in vitro</i>

research Type 2 Cytokine–Dependent Skin Barrier Regulation in Personalized 2-Dimensional and 3-Dimensional Skin Models of Atopic Dermatitis: A Pilot Study

research Natural Product-Inspired Bis(trifluoromethyl) Phenyl Hydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitors of Human Steroid 5α-Reductase Type-1: Synthesis, In Vitro</i>, and In Silico* Studies*

research Skin and hair on-a-chip: in vitro skin models versus ex vivo tissue maintenance with dynamic perfusion

research Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo

research A novel control of human keratin expression: cannabinoid receptor 1-mediated signaling down-regulates the expression of keratins K6 and K16 in human keratinocytesin vitro</i>andin situ

research Effects of epidermal growth factor, fibroblast growth factor, minoxidil and hydrocortisone on growth kinetics in human hair bulb papilla cells and root sheath fibroblasts cultured in vitro

research Pitx2, a β-catenin-regulated transcription factor, regulates the differentiation of outer root sheath cells cultured in vitro

research Endocrine controls of primary adult human stem cell biology: Thyroid hormones stimulate keratin 15 expression, apoptosis, and differentiation in human hair follicle epithelial stem cells in situ and in vitro

research VEGF165 modulates proliferation, adhesion, migration and differentiation of cultured human outer root sheath cells from central hair follicle epithelium through VEGFR-2 activation in vitro

research Arabidopsis thaliana as a model system for the study of the effect of inoculation by azospirillum brasilense Sp-245 on root hair growth

research Conditioned medium from primary cytotrophoblasts, primary placenta-derived mesenchymal stem cells, or sub-cultured placental tissue promoted HUVEC angiogenesis in vitro

research Cultured dermal papilla cells of the rat vibrissa follicle. Proliferative activity, adhesion properties and reorganization of the extracellular matrix in vitro

research Hair growth in vitro from histocultured skin

research Anticancer effects of metformin on neuroendocrine tumor cells in vitro

research Formulation of Chitosan-Coated Brigatinib Nanospanlastics: Optimization, Characterization, Stability Assessment and In-Vitro Cytotoxicity Activity against H-1975 Cell Lines

research Effects of dihydrotestosterone on rat dermal papilla cells in vitro

research ProjectH: a collaborative quantitative study of computer-mediated communication

research Investigation of age-related decline of microfibril-associated glycoprotein-1 in human skin through immunohistochemistry study