3 citations
,
May 2022 in “Dermatologic surgery” Exosomes could help with skin and hair, but more research and better methods are needed.
18 citations
,
September 2023 in “Experimental Dermatology” The skin microbiome plays a key role in treating atopic dermatitis.
January 2026 in “Lab on a Chip” Organoids and hair-on-chip technologies show promise for hair regeneration but face clinical challenges.
19 citations
,
January 2008 in “Journal of Pharmacy and Pharmacology” Porcine hair follicles can effectively model human hair follicles for drug absorption.
28 citations
,
November 1987 in “Journal of the American Academy of Dermatology” The model successfully grew and differentiated hair follicle cells in the lab.
54 citations
,
March 1991 in “Proceedings of the National Academy of Sciences” This model can replace animal testing for quick, cost-effective skin toxicity tests.
1 citations
,
August 2025 in “Frontiers in Bioengineering and Biotechnology” A 3D skin model helps study wound healing better than traditional methods.
7 citations
,
July 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” Passage numbers affect cell growth and experiment results.
March 2020 in “Central European Journal of Biology” The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.
September 2019 in “Journal of Investigative Dermatology” Researchers developed a 3D skin model with its own immune and blood vessel cells to better understand skin health and disease.
29 citations
,
April 2003 in “Experimental dermatology” Human hair follicles grown in vitro maintain normal keratin patterns and structure.
March 2026 in “Experimental Dermatology” The new model helps understand and develop treatments for genetic skin disorders like AEC.
Mouse hair follicles grow best in a special medium, especially when cut and from adult mice.
39 citations
,
March 2022 in “Nature Protocols” Scientists created hair-growing skin models from stem cells, which could help treat hair loss and skin diseases.
27 citations
,
June 2015 in “Journal of photochemistry and photobiology. B, Biology” The new lab-grown skin model is good for testing sunscreen's protection against DNA damage from UV light.
29 citations
,
May 2007 in “International journal of pharmaceutics” Different compounds move through artificial sebum at different rates, which can help choose the best ones for targeting hair follicles.
TGF-β1 and FGF-18 are key in hair loss, and Minoxidil helps hair growth.
April 2023 in “Journal of Investigative Dermatology” The research developed methods to test drugs that could protect and restore hair follicle protection in a hair loss condition.
April 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Topical folates can penetrate skin and enhance wound healing.
19 citations
,
July 2017 in “PLoS ONE” Cell characteristics change with passage numbers, affecting experiment results.
Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.
4 citations
,
September 2024 in “Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics” 3D models and organoids improve liposarcoma research and therapy development.
1 citations
,
November 2022 in “Pharmaceutical research” The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.
2 citations
,
January 2020 in “Methods in molecular biology” Scientists created early-stage hair follicles from human skin cells, which could help treat baldness and study hair growth.
59 citations
,
August 2014 in “International Journal of Biological Macromolecules” The study found an efficient method to extract antioxidants from Hibiscus leaves.
46 citations
,
August 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” Phosphatidic acid may help hair grow by affecting cell growth pathways.
21 citations
,
April 2021 in “Biofabrication” The study created a skin model with realistic blood vessels that improves skin grafts and testing for drug delivery.
7 citations
,
September 2021 in “Antimicrobial Agents and Chemotherapy” Olorofim effectively treats fungal skin infections.
March 2025 in “Molecules” Tectona grandis leaf extracts, especially with propylene glycol, may be promising for topical hair loss treatments.
January 2022 in “International Journal of Medical Sciences” Cedrol may be an effective treatment for colorectal cancer.