research KF19418, a new compound for hair growth promotion in vitro and in vivo mouse models
KF19418 promotes hair growth similarly to minoxidil but is not better in live mice.
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research Development of finasteride/PHBV@polyvinyl alcohol/chitosan reservoir-type microspheres as a potential embolic agent: from in vitro</i> evaluation to animal study
Created microspheres show potential for safe and effective use in prostate artery embolization.
research Human hair follicle and interfollicular keratinocyte reactivity to mouse HPV16-transformed cells: An in vitro study
HPV16-transformed cells can change human skin cell properties, aiding tumor growth.
research SELF-ASSEMBLED CHITOSAN NANOPARTICLES FOR PERCUTANEOUS DELIVERY OF CAFFEINE: PREPARATION, CHARACTERIZATION AND IN VITRO RELEASE STUDIES
Chitosan nanoparticles are promising for sustained caffeine delivery through the skin.
research Effects of the selective TrkA agonist gambogic amide on pigmentation and growth of human hair follicles in vitro
Gambogic Amide helps maintain hair color and promotes hair growth.
research Protective effects of Ecklonia cava extract on the toxicity and oxidative stress induced by hair dye in in-vitro and in-vivo models
Ecklonia cava extract can reduce the damage and stress caused by hair dye.
research Differentiation of nestin-negative human hair follicle outer root sheath cells into neurons in vitro
Human hair follicle cells can be turned into neural stem cell-like cells, which might help treat brain diseases.
research Hot water extract of oriental melon leaf promotes hair growth and prolongs anagen hair cycle: In vivo and in vitro evaluation
Oriental melon leaf extract may help hair grow and keep it in the growing phase longer.
research Safety and biopsy outcomes of a topical treatment (SM04554) for male androgenetic alopecia (AGA): Results from a phase 2, multicenter, randomized, double-blind, vehicle-controlled trial
Topical treatment SM04554 safely promotes hair growth in male baldness.
research Comparison of the response of secondary hair follicles of cashmere and angora goats to prolactin and melatonin in vitro</i>
Prolactin and melatonin affect the growth of Angora and Cashmere goat hair differently.
research Enhancement of skin rejuvenation and hair growth through novel near-infrared light emitting diode (nNIR) lighting: in vitro and in vivo study
Near-infrared LED light improves skin rejuvenation and hair growth better than white LED light.
research Hair Tonic Formulation Containing Ethyl Acetate Fraction of Sweet Potato (Ipomoea batatas (L.) Lamk) Leaves and In Vitro Anti-Dandruff Activity Test against Malassezia Furfur
Sweet potato leaf extract can effectively treat dandruff.
research Peer Review #1 of "Induced pluripotent stem cells from human hair follicle keratinocytes as a potential source for in vitro hair follicle cloning (v0.1)"
Human hair follicle cells can be turned into stem cells that may help clone hair for treating hair loss or burns.
research The importance of dual 5α-reductase inhibition in the treatment of male pattern hair loss: Results of a randomized placebo-controlled study of dutasteride versus finasteride
Dutasteride more effective for hair growth, but has more side effects than finasteride.
research Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo
Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
research The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results
Both mouse and rat models are effective for testing alopecia areata treatments.
research Development of Liposomal Systems of Finasteride for Topical Applications: Design, Characterization, and In Vitro Evaluation
Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.
research Pitx2, a β-catenin-regulated transcription factor, regulates the differentiation of outer root sheath cells cultured in vitro
Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.
research Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures
Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.
research Treatment of telogen effluvium using a dietary supplement containing Boswellia serrata , Curcuma longa , and Vitis vinifera : Results of an observational study
A dietary supplement with Boswellia serrata, Curcuma longa, and Vitis vinifera showed potential improvement in hair health for telogen effluvium patients, but more research is needed.
research Inhibitory activities of some traditional Chinese herbs against testosterone 5α-reductase and effects of Cacumen platycladi on hair re-growth in testosterone-treated mice
Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.
research Allergens of permanent hair dyes induces epidermal damage, skin barrier loss and IL-1 α increase in epidermal in vitro model
Permanent hair dye mixtures can irritate and damage the skin.
research 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro
11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.
research Effects of dobutamine on cyclic AMP accumulation induced by the stimulation of dopamine receptors in rabbit retina in vitro
Dobutamine does not mimic dopamine at therapeutic doses but may at very high concentrations; microfilaments, not microtubules, are important for wound healing in Xenopus embryos.
research Brassica oleracea extract, glucosinlates, and sulforaphane promote hair growth in vitro and ex vivo
Brassica oleracea extract, glucosinlates, and sulforaphane can boost hair growth and might be used to treat hair loss.
research Reduction of telogen rate and increase of hair density in androgenetic alopecia by a cosmetic product: Results of a randomized, prospective, vehicle‐controlled double‐blind study in men
Cosmetic foam product reduces hair loss and increases hair density in men.
research Conditioned medium from human adipose-derived mesenchymal stromal cells can modulate cell migration and morphology of keratinocytes in vitro
MSC-CM can boost skin cell growth and movement, aiding skin repair.
research DEVELOPING NEW DUAL-ACTION ANTIVIRAL/ANTI-INFLAMMATORY SMALL MOLECULES FOR COVID-19 TREATMENT USING IN SILICO AND IN-VITRO APPROACHES
Hit15 shows promise as a COVID-19 treatment by reducing virus infection and inflammation.
research Optimal concentration selection of active pharmaceutical ingredients in the cream-mask intended for androgenic alopecia treatment according to experimental results on paramecium caudatum biological model
The best mix for a hair loss treatment cream is 10% Sophora japonica tincture and 5% Serenoa repens extract.
research Efficacy and safety of a dietary supplement containing a lipid co-extract from Serenoa repens and Pygeum africanum for the treatment of androgenetic alopecia (AGA) in women. Results of a randomized, double-blind, placebo-controlled clinical trial
The supplement with Serenoa repens and Pygeum africanum significantly increased active hair growth and decreased rest phase hair in post-menopausal women with hair loss, with only mild digestive side effects.