81 citations
,
June 2014 in “American Journal of Men's Health” Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.
34 citations
,
December 2021 in “Journal of Clinical Medicine” Men with BPH should discuss potential sexual side effects with doctors before treatment, as some treatments can affect ejaculation.
3 citations
,
July 2021 in “Urology Herald” COVID-19 may affect reproductive and urinary systems, needing more research for better care.
September 2022 in “Frontiers in genetics” A Chinese male with a new genetic mutation has a skin condition and severe urinary issues, with treatments having mixed success.
36 citations
,
March 2014 in “Cell death and differentiation” Disrupting β-catenin signaling in certain cells causes anorectal malformations.
October 2013 in “The American Journal of Gastroenterology” Colonic lipomas can cause complications like intussusception, requiring surgery if symptoms occur.
April 2022 in “The Journal of Sexual Medicine” Treating hematospermia can improve sexual function and reduce anxiety.
49 citations
,
December 2007 in “Fertility and Sterility” Stopping finasteride improved sperm counts in two men, reducing the need for fertility treatments.
January 2001 in “亚洲男性学杂志:英文版” Men's fertility and sexual health decline with age, but some remain fertile into their eighties.
May 2021 in “Journal of the Endocrine Society” Long-term opioid use can cause a serious condition where the adrenal glands don't work properly, which doctors should watch out for.
February 2026 in “PubMed” Finasteride withdrawal causes anxiety-like behavior in male rats.
December 2017 in “Reactions Weekly” Finasteride caused bleeding in a man, which stopped after stopping the drug.
26 citations
,
December 2019 in “Neurobiology of Stress” Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.
4 citations
,
October 2022 in “Current Urology” Platelet-rich plasma shows promise in reducing pain for bladder pain syndrome.
March 2018 in “European Urology Supplements” Patients follow treatment well, but many change medicines; good information helps compliance.
September 2025 in “Healthcare” SSRIs may help manage sexual behavior in dementia patients, but they can cause long-lasting sexual dysfunction.
4 citations
,
December 2010 in “Journal of the American Geriatrics Society” Thalamic stroke can cause delirium without other symptoms, especially in older adults.
Waking up to urinate at night (nocturia) is linked to higher death rates, but the exact reason is unknown.
March 2008 in “European Urology Supplements” Finasteride and dutasteride can affect sexual function in BPH patients.
3 citations
,
July 2014 in “Indian Journal of Surgery” Sex hormones might influence bladder cancer development, and aromatase inhibitors could increase risk in postmenopausal women.
September 2021 in “Authorea (Authorea)” Systemic lupus erythematosus caused severe abdominal issues in a Sudanese woman.
January 2019 in “Nihon Yakuri Gakkai nenkai yoshishu” Current treatments for lower urinary tract symptoms include α1-blockers, 5ARIs, PDE5 inhibitors, anticholinergic agents, and β3-adrenergic receptor agonists.
18 citations
,
August 2011 in “Medical Hypotheses” Physical inactivity is a primary cause of many human illnesses.
July 2013 in “Pharmaceutical Regulatory Affairs Open Access” Invasomes with 0.5% limonene greatly improve skin delivery of finasteride.
November 2003 in “PubMed”
3 citations
,
June 1987 in “British Journal of Dermatology” Nifedipine may help treat perniosis, improving symptoms and clearing lesions for some patients.
January 2014 in “Hebei yixue” Combining tamsulosin and finasteride effectively improves urinary symptoms in elderly BPH patients.
January 2017 in “Clinical pharmacist” Long use of finasteride and dutasteride can cause long-term erection problems.
20 citations
,
September 2019 in “Epidemiology and Psychiatric Sciences” SSRI antidepressants can cause long-lasting sexual problems.