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GlossaryIncreased Insulin Requirement

need for more insulin to control blood sugar levels

Increased Insulin Requirement refers to the need for a higher dose of insulin to maintain normal blood sugar levels. This can occur due to various factors such as stress, illness, hormonal changes, or insulin resistance, where the body's cells become less responsive to insulin. For individuals with diabetes, this means they may need to adjust their insulin dosage to effectively manage their condition.

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research Cushing's syndrome due to pharmacological interaction in a cystic fibrosis patient

37 citations , September 2002 in “Acta pædiatrica”

A cystic fibrosis patient developed Cushing's syndrome from a drug interaction between itraconazole and budesonide, which improved after stopping the medications.

research Diabetes in a Bearded Woman

4 citations , June 2005 in “Andrology”

A woman's diabetes improved after removing ovarian tumors that caused high testosterone levels.

Immediate and Delayed Complications of Dexamethasone Cyclophosphamide Pulse Therapy

research Immediate and Delayed Complications of Dexamethasone Cyclophosphamide Pulse (DCP) Therapy

20 citations , October 2003 in “The Journal of Dermatology”

DCP therapy causes side effects like weakness, flushing, headaches, and taste changes, but less frequently causes hypertension and diabetes.

Severe Insulin Resistance in a Pediatric Patient: Key Areas to Address in Screening

research Severe Insulin Resistance in a Pediatric Patient: Key Areas to Address in the Screening

March 2013 in “Journal of pediatric nursing”

The case emphasizes the need for careful screening in children for insulin resistance and related conditions.

research Are Women with Polycystic Ovary Syndrome at Increased Risk of Alzheimer Disease? Lessons from Insulin Resistance, Tryptophan and Gonadotropin Disturbances and Their Link with Amyloid-Beta Aggregation

4 citations , July 2024 in “Biomolecules”

Women with PCOS may have a higher risk of Alzheimer's disease.

Prevalence of Clinical Manifestations Associated With Insulin Resistance Among Female Medical Students in Saudi Arabia

research Prevalence of Clinical Manifestations Known to Be Associated With Insulin Resistance Among Female Medical Students of a Private College in Saudi Arabia

November 2024 in “Cureus”

Many female medical students in Saudi Arabia show signs of insulin resistance linked to increased waist size.

Insulin Resistance as a Risk Factor for the Development of Type 2 Diabetes Mellitus: A Systematic Approach

research Insulin resistance as risk factor for the development of type 2 diabetes mellitus: a systematic approach

December 2021 in “Acta Marisiensis”

Insulin resistance increases the risk of developing type 2 diabetes and other health issues.

research Metabolic risk in PCOS: phenotype and adiposity impact

162 citations , January 2015 in “Trends in Endocrinology and Metabolism”

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

research Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth

222 citations , January 2014 in “International journal of reproductive medicine”

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Pro-Insulin-Like Growth Factor-II Ameliorates Age-Related Inefficient Regenerative Response by Orchestrating Self-Reinforcement Mechanism of Muscle Regeneration

research Pro-Insulin-Like Growth Factor-II Ameliorates Age-Related Inefficient Regenerative Response by Orchestrating Self-Reinforcement Mechanism of Muscle Regeneration

19 citations , April 2015 in “Stem Cells”

Pro-IGF-II improves muscle repair in old mice.

Metabolic Syndrome and Insulin Resistance Syndrome Among Infertile Women with Polycystic Ovary Syndrome: A Cross-Sectional Study from Central Vietnam

research Metabolic Syndrome and Insulin Resistance Syndrome among Infertile Women with Polycystic Ovary Syndrome: A Cross-Sectional Study from Central Vietnam

14 citations , January 2018 in “Endocrinology and Metabolism”

Many infertile women with PCOS in Central Vietnam have metabolic or insulin resistance syndrome, with obesity and older age increasing the risk.

research Cardiometabolic and neuroimaging correlates of cognitive function in polycystic ovary syndrome

1 citations , January 2017 in “Spectrum Research Repository (Concordia University)”

Women with PCOS have altered brain structure and reduced cognitive performance.

Hair Loss: A Harbinger of Morbidities to Come

research Hair Loss: A Harbinger of the Morbidities to Come!

1 citations , January 2012 in “International Journal of Trichology”

Early hair loss in men and women may indicate a higher risk of heart disease and metabolic problems.

research Hair growth promoting effect and action mechanism of Chrysanthemum zawadskii extract

January 2014

Chrysanthemum zawadskii extract may help treat hair loss by promoting hair growth and affecting growth factors.

Update: The Pathogenesis and Treatment of Polycystic Ovary Syndrome

research Update: The Pathogenesis and Treatment of PCOS

11 citations , July 2003 in “The Nurse practitioner”

New treatments for PCOS focus on managing symptoms and improving fertility.

research The frequency of polycystic ovary syndrome in women with prediabetes compared with normoglycemic women

November 2025 in “Frontiers in Endocrinology”

Women with prediabetes may have a higher risk of PCOS-like changes, especially if they have impaired glucose tolerance.

Extracellular Vesicles Derived from MSCs Activate Dermal Papilla Cells In Vitro and Promote Hair Follicle Conversion from Telogen to Anagen in Mice

research Extracellular vesicles derived from MSCs activates dermal papilla cell in vitro and promotes hair follicle conversion from telogen to anagen in mice

113 citations , November 2017 in “Scientific Reports”

Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.

research Role of Oxidative Stress in Obese and Nonobese PCOS Patients

12 citations , January 2022 in “International Journal of Clinical Practice”

Oxidative stress is higher in women with PCOS, especially if they're obese, and it may increase their risk of heart disease.

research The good, the bad, and the ugly facets of insulin resistance

11 citations , January 2020 in “Medical Journal Armed Forces India”

Insulin resistance is a complex condition that can lead to many diseases and has few treatment options.

research Changes in Prolactin and Insulin Resistance in PCOS Patients Undergoing Metformin Treatment: A Retrospective Study

1 citations , December 2024 in “Journal of Clinical Medicine”

Lower baseline prolactin levels may lead to better insulin resistance improvement with metformin in PCOS patients.

research Lab Quality Management and Methodology

January 2015 in “Indian Journal of Medical Biochemistry”

Men with early balding should be checked for metabolic syndrome, as there's a link between the two.

research Linking diet to acne metabolomics, inflammation, and comedogenesis: an update

138 citations , July 2015 in “Clinical, Cosmetic and Investigational Dermatology”

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

research Endocrine and Reproductive Effects of Polycystic Ovarian Syndrome

18 citations , December 2014 in “Obstetrics and Gynecology Clinics of North America”

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

research A patient with combined polycystic ovary syndrome and autoimmune polyglandular syndrome type 2

9 citations , January 2007 in “Gynecological Endocrinology”

A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.

research The Polycystic Ovary Syndrome and Acne

2 citations , January 2014 in “Springer eBooks”

Polycystic Ovary Syndrome (PCOS) often leads to severe acne, and lifestyle changes and hormonal treatments can help manage it.

research Gynecologic and andrologic dermatology and the metabolic syndrome

14 citations , September 2017 in “Clinics in Dermatology”

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

research Metabolic dysfunction in female mice with disruption of 5α-reductase 1

11 citations , January 2017 in “Journal of Endocrinology/Journal of endocrinology”

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

research Diagnosis of Polycystic Ovary Syndrome

97 citations , February 2007 in “Clinical Obstetrics and Gynecology”

The definition of Polycystic Ovary Syndrome may change with new research, and careful screening is key for managing the condition.

research The Biomedical Role of Zinc in the Functioning of the Human Organism

5 citations , December 2014 in “Polish Journal of Public Health”

Zinc is essential for many body functions and imbalances can lead to health problems.

Polycystic Ovary Syndrome: Comprehensive Overview

research Polycystic Ovary Syndrome

257 citations , July 2018 in “Obstetrics & Gynecology”

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.