277 citations
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July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
185 citations
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February 2018 in “Journal of Investigative Dermatology” Melatonin may benefit skin health and could be a promising treatment in dermatology.
138 citations
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June 2023 in “Molecules” Skin pigmentation varies due to genetics, UV exposure, and drugs, with treatments available but requiring medical advice.
124 citations
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December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
122 citations
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April 1995 in “Journal of Cutaneous Pathology” The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.
116 citations
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April 2002 in “American journal of veterinary research” Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.
112 citations
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July 1998 in “Journal of Investigative Dermatology” Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.
67 citations
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September 2003 in “Journal of cutaneous pathology” Skin problems are very common in people with end-stage kidney disease.
62 citations
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April 2009 in “British Journal of Dermatology” Epidermal stem cells could lead to new treatments for skin and hair disorders.
59 citations
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April 2016 in “Cell Reports” EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.
53 citations
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April 2018 in “Journal of The American Academy of Dermatology” Cancer treatments often cause hair disorders, significantly affecting patients' quality of life, and better management methods are needed.
39 citations
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November 2017 in “Journal of The American Academy of Dermatology” The document suggests using standardized methods to track and measure hair loss in alopecia areata, including patient self-assessment and a 50% improvement in specific scores as a treatment goal.
34 citations
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January 2014 in “International Journal of Trichology” Polarized dermoscopy is slightly better than nonpolarized for diagnosing hair disorders, with each method having its own strengths.
22 citations
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February 2008 in “Journal of Dermatological Science” EPR spectroscopy showed that spontaneous hair growth results in thicker skin and less pigmented hair than depilation-induced growth.
21 citations
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July 2017 in “Journal of Cosmetic and Laser Therapy” Vesicular carriers like liposomes may improve cosmetic skin treatment delivery and effectiveness but need more human research.
19 citations
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May 2005 in “Archives of Environmental & Occupational Health” All immigrant workers in the study had skin problems, with fungal nail infections, athlete's foot, and acne or folliculitis being most common, affecting their quality of life, yet they didn't seek medical help.
18 citations
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October 2023 in “Nature Communications” Men with baldness are more prone to skin cancers on the scalp due to sun exposure, not testosterone.
18 citations
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January 2020 in “Ecology and evolution” Genes related to pigmentation, body rhythms, and behavior change during hares' seasonal coat color transition, with a common genetic mechanism in two hare species.
15 citations
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November 2015 in “Trends in biotechnology” Gene regulation could revolutionize hair color by altering pigmentation from within.
15 citations
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February 2015 in “Cell & tissue research/Cell and tissue research” P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.
13 citations
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July 2012 in “Pigment Cell & Melanoma Research” A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
12 citations
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June 2003 in “Journal of the European Academy of Dermatology and Venereology” Some psychoactive drugs can cause skin reactions, with carbamazepine having a higher risk, and stopping the drug and seeing a dermatologist is important.
11 citations
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May 2012 in “Genesis” Bmpr2 and Acvr2a receptors are crucial for hair retention and color.
10 citations
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May 1986 in “Experientia” Too much zinc in the diet can cause hair loss and color change in young mice by reducing copper in the body.
9 citations
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July 2022 in “Cell reports” Sox2 controls hair color by affecting pigment production in hair follicles.
9 citations
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June 1959 in “Archives of dermatology” Hair can darken after inflammation and then return to its original color.
8 citations
,
January 2017 in “Stem Cells International” A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
6 citations
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November 2013 in “International Journal of Radiation Biology” Gamma-rays exposure during the resting phase of hair growth can damage hair regeneration and color in mice.
3 citations
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January 2012 in “Wageningen Academic Publishers eBooks” Hair health depends on various factors and hair loss can significantly affect a person's well-being; understanding hair biology is key for creating effective hair care treatments.
3 citations
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May 2010 in “Archives of dermatology” Herpes zoster infection can cause permanent hair color change in the affected area.