research Synthesis and biological evaluation of 3-tetrazolo steroidal analogs: Novel class of 5α-reductase inhibitors
3-tetrazolo steroidal analogs can strongly inhibit the enzyme linked to hair loss.
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720-750 / 1000+ resultsresearch Social isolation‐induced increase in α4and δ subunit gene expression is associated with a greater efficacy of ethanol on steroidogenesis and GABAAreceptor function
Social isolation makes rats more sensitive to alcohol's effects on the brain.
research Small Molecule Inhibitors and Inflammatory Skin Diseases
New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.
research Activation of the OVOL1-OVOL2 Axis in the Hair Bulb and in Pilomatricoma
The genes OVOL1 and OVOL2 are important for hair growth and may be involved in a type of skin tumor.
research GC-MS analysis and phytochemical screening of methanolic fruit extract of Citrullus colocynthis (L.) Schrad
The methanolic fruit extract of Citrullus colocynthis contains bioactive compounds that may support its use in traditional medicine and drug development.
research FORMULATION AND EVALUATION OF PHYTO-HYDROGEL CONTAINING AZADIRACHTA INDICA AND TRIDAX PROCUMBENS FOR THE TREATMENT OF SEBORRHEIC DERMATITIS
The hydrogel with neem and tridax extracts effectively treats seborrheic dermatitis.
research MLO ‐mediated Ca2+ influx regulates root hair tip growth in Arabidopsis
MLO proteins help regulate calcium and ROS levels, promoting root hair growth in Arabidopsis.
research Increased anxiety‐like phenotype in female guinea pigs following reduced neurosteroid exposure in utero
Female guinea pigs exposed to less allopregnanolone before birth showed more anxiety-like behavior.
research Mechanism of progesterone neuroprotection of rat cerebellar Purkinje cells following oxygen–glucose deprivation
Progesterone protects rat brain cells by enhancing GABA A receptor activity.
research Innate knowledge of herbal medicine among the Sonowal Kachari tribe of Lakhimpur district, Assam, India
The Sonowal Kachari tribe uses 39 plants for medicine, mainly leaves, showing their valuable herbal knowledge.
research Antioxidant Properties of Platycladus orientalis Flavonoids for Treating UV-Induced Damage in Androgenetic Alopecia Hair
Platycladus orientalis flavonoids protect balding hair from UV damage and slow hair color change.
research Characteristics of Households Experiencing Housing Instability
Herbal extract may help treat certain types of hair loss.
research Recalcitrant alopecia areata responsive to leflunomide and anthralin—Potentially undiscovered JAK /STAT inhibitors?
Leflunomide and anthralin may effectively treat severe alopecia areata.
research Oleanolic acid alleviates stress-induced alopecia via modulating brain-skin axis: Neuroprotection and dermal papilla cell senescence
research Dark cytotoxicity beyond photo-induced one of silica nanoparticles incorporated with RuII nitrosyl complexes and luminescent {Mo6I8} cluster units
research Intralesional steroids for alopecia areata
Intralesional steroids can help regrow hair in some alopecia areata patients but have side effects.
research Synthesis, Biological Evaluation and in silico Studies of Novel 5α-aza-Bhomo-3,5-secosteroids as Potential 5-reductase Inhibitors
research Comprehensive Evaluation of Tectona grandis L.f.: Integrated In Vitro and In Silico Analysis of Steroid 5α-Reductase Inhibition and Anti-Inflammatory Properties
Teak leaf extract may help hair growth and reduce inflammation safely.
research An in Vitro Approach: Antibacterial Activity of Sansevieria trifasciata Prain. Leaves with Chemometric Analysis
Sansevieria trifasciata leaves have strong antibacterial effects similar to ciprofloxacin.
research Auxin signaling gets oxidative to promote root hair growth
Auxin promotes root hair growth through oxidative processes involving reactive oxygen species.
research Cytotoxic and antioxidant effect of the ethanolic extract of Citrullus colocynthis L. plant fruit
Citrullus colocynthis fruit extract has strong antioxidant and cancer-fighting potential.
research Chemotherapy-Induced Alopecia Beyond Cytotoxicity: Hair Follicle Immune Privilege Collapse and JAK-STAT Signaling
Chemotherapy-induced hair loss may be linked to immune system changes, and certain treatments could help but need careful use.
research Role of Neurosteroidogenic Pathways in the Antiseizure Activity of Midazolam in the 6‐Hz and Kindling Models of Epilepsy
Midazolam's antiseizure effects are mainly due to synaptic GABA-A receptors, not neurosteroids or extrasynaptic receptors.
research Amygdalin ameliorates alopecia areata on C3H/HeJ mice by inhibiting inflammation through JAK2/STAT3 pathway
research Indulekha Bringha hair oil significantly improves hair density and reduces hair fall from roots in comparison to coconut oil in a randomized, single blinded, placebo-controlled clinical trial
Indulekha Bringha oil improves hair growth and reduces hair fall better than coconut oil.
research JAK Inhibitors: A New Weapon in the Skin Care Providers' Arsenal.
JAK inhibitors show promise in treating difficult skin diseases.
research Efficacy of Azadirachta indica and Zingiber officinale on Hirsutism in Polycystic Ovarian Disease: A Randomized Controlled Trial
Neem and Zanjabeel are as effective as standard drugs for treating hirsutism in PCOD patients.
research An Intensive Study on Curcuma longa and Dalbergia sissoo as Possible Promising Combination for the Treatment of Various Ailments
Curcuma longa and Dalbergia sissoo may work well together to treat inflammation, stress, and cancer.
research In silico investigation of possible multi-target drugs against Glutamate S-transferase and prolyl tRNA synthetase in Onchocerca volvulus
Bedaquiline, Telmisartan, Diosmin, Azelastine, and Adapalene may be effective treatments for onchocerciasis.
research EXPLORATION OF MEDICINAL PLANTS USED BY THE MALAYALI TRIBES OF KOLLI HILLS, TAMILNADU, INDIA
Medicinal plants are vital for Malayali tribes' health, and preserving this knowledge is important.