research T-Cell Reconstitution after Thymus Xenotransplantation Induces Hair Depigmentation and Loss
T-cell reconstitution after thymus transplantation can cause hair whitening and loss.
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research Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice
Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
research Critical Role of ATP-P2X7 Axis in UV-Induced Melanogenesis
ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.
research Change in Hair Color in Mice Induced by Injection of α-MSH
Injecting α-MSH made mice's hair turn black.
research Therapeutic effects of topical Mycophenolate mofetil on hydroquinone-induced depigmentation in Guinea pigs and mice
Mycophenolate mofetil may safely help restore skin color in depigmentation conditions.
research The Effect of Butin on the Vitiligo Mouse Model Induced by Hydroquinone
Butin is effective in treating vitiligo in mice.
research Topical RT1640 treatment effectively reverses gray hair and stem cell loss in a mouse model of radiation‐induced canities
RT1640 treatment reverses gray hair and promotes hair growth in mice.
research On the Role of Melatonin in Skin Physiology and Pathology
Melatonin is important for skin health and protection, and can be made by the skin or applied to it.
research Next generation human skin constructs as advanced tools for drug development
Advanced human skin models improve drug development and could replace animal testing.
research Stem Cells and their Niches
The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
research Pathogenesis and regenerative therapy in vitiligo and alopecia areata: focus on hair follicle
Hair follicles are key to treating vitiligo and alopecia areata, but challenges exist.
research Alopecia areata and subsequent Marie Antoinette syndrome following COVID-19 infection and vaccination: A case report
COVID-19 infection and vaccination may trigger hair loss and rapid hair whitening.
research How the stress of fight or flight turns hair white
Stress turns hair white by depleting color-giving cells in hair follicles through a specific neurotransmitter related to the body's stress response.
research Field melanin mapping of the hairless scalp
The study found a specific pattern of uneven melanin distribution on balding scalps that could help understand skin diseases caused by light exposure.
research Editorial: Advances and novel intervention in photodermatology
New insights into skin damage from UV exposure suggest potential treatments, including targeting specific RNAs and combining therapies for better outcomes.
research 285 A new scalp treatment for anti-ageing hair
The new scalp treatment preserves hair color, reduces hair loss, and maintains hair strength.
research Clinical Snippets
Increased pigmentation may protect skin from UVB, new targets for skin disease treatments were identified, sunscreen ingredients don't affect hormones, TNF-α inhibitors may help diabetic wounds, and certain treatments could prevent chemotherapy-induced hair loss.
research Bilateral Eyelash Poliosis with Raccoon Erythema and Hypopigmentation-Contact Follicular Leukoderma
Topical eyedrops may cause eyelash whitening and skin lightening around the eyes.
research Alex de la Iglesia: "Todos somos perversos"
Bcl-2 affects hair growth and pigmentation by controlling cell death.
research Lipid‐mediated signalling and melanocyte function
A sphingolipid from human placenta may help treat vitiligo by activating melanocyte stem cells.
research In vitro Differentiation of Melanocyte Stem Cells Derived from Vitiligo Patients into Functional Melanocytes
Melanocyte stem cells from non-affected skin in vitiligo patients can become functional melanocytes for potential therapy.
research Regeneration of Mouse Skin Melanocyte Stem Cells In Vivo and In Vitro
The research found ways to activate melanocyte stem cells for potential treatment of skin depigmentation conditions.
research Do Hair Bulb Melanocytes Undergo Apotosis During Hair Follicle Regression (Catagen)?
Hair follicle melanocytes die during hair regression.
research Structure and function of melanocytes: microscopic morphology and cell biology of mouse melanocytes in the epidermis and hair follicle.
Mouse melanocyte structure and function are influenced by genetics, hormones, and environmental factors.
research Repigmentation through Melanocyte Regeneration in Vitiligo
UV light can help stimulate the growth of new pigment cells from hair follicles in people with vitiligo.
research Endothelin-1 combined with extracellular matrix proteins promotes the adhesion and chemotaxis of amelanotic melanocytes from human hair follicles in vitro
Endothelin-1 helps amelanotic melanocytes stick and move better on certain proteins.
research Overexpression of hepatoma-derived growth factor in melanocytes does not lead to oncogenic transformation
Overexpression of HDGF in melanocytes does not cause cancer.
research Detection of Functionally Active Melanocortin Receptors and Evidence for an Immunoregulatory Activity of α-Melanocyte-Stimulating Hormone in Human Dermal Papilla Cells
αMSH may help regulate immune responses in hair follicles and its disruption could lead to hair loss.
research Betamethasone actives cultured amelanotic melanocytes derived from outer root sheath of human hair follicle
Betamethasone activates and increases the growth of certain skin cells from hair follicles.
research Inducible cre-mediated N-ras activation and PTEN inactivation in transgenic mouse melanocytes requires keratinocyte hyperplasia to elicit a melanocyte pathology
Melanocyte pathology requires keratinocyte hyperplasia and regulation dysfunction.