research Diffuse Alopecia Areata
Diffuse alopecia areata causes widespread hair thinning due to an autoimmune response.
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810-840 / 1000+ resultsresearch Role of Human Skin Antimicrobial Peptides in Psoriasis
Inflammation in psoriasis may trigger antimicrobial peptides and cell death.
research 415 Targeting inflammation and specialized pro-resolving mediators to reinforce barrier function and scalp homeostasis.
Targeting inflammation can improve scalp and hair health.
research Novel potential therapeutic targets of alopecia areata
New treatments for hair loss from alopecia areata may include targeting immune cells, using stem cells, balancing gut bacteria, applying fatty acids, and using JAK inhibitors.
research AIRE Deficiency Leads to the Development of Alopecia Areata‒Like Lesions in Mice
AIRE deficiency causes hair loss similar to alopecia areata in mice.
research CD4+CD25+FoxP3+ Regulatory Tregs inhibit fibrocyte recruitment and fibrosis via suppression of FGF-9 production in the TGF-β1 exposed murine lung
Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.
research Advances in molecular pathogenesis of hidradenitis suppurativa: Dysregulated keratins and ECM signaling
Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.
research Editorial: Advances and novel intervention in photodermatology
New insights into skin damage from UV exposure suggest potential treatments, including targeting specific RNAs and combining therapies for better outcomes.
research The Roles of Keratinocytes in the Initiation, Progression and Maintenance of Hidradenitis Suppurativa
Keratinocytes contribute to hidradenitis suppurativa by causing inflammation and worsening the condition.
research Present and Future Use of Exosomes in Dermatology
Exosomes could be key in treating skin conditions and healing wounds.
research Complete Blood Collection-based Systemic Inflammation Biomarkers as a Severity Biomarker in Alopecia Areata: A Cross-sectional Study
Higher inflammation markers are linked to more severe alopecia areata.
research Hair follicle is a target of stress hormone and autoimmune reactions
Stress hormones and autoimmune reactions can cause hair loss.
research Etiology of cicatricial alopecias: a basic science point of view
Cicatricial alopecia may be caused by immune attacks on hair follicles, gland issues, or stem cell damage.
research Cutaneous immunopathology of androgenetic alopecia.
Inflammation, possibly triggered by a specific bacteria and activated by UV radiation, may contribute to male pattern baldness.
research Jieduquyuziyin prescription alleviates SLE complicated by atherosclerosis via promoting cholesterol efflux and suppressing TLR9/MyD88 activation
Jieduquyuziyin prescription helps treat SLE with atherosclerosis by improving cholesterol removal and reducing inflammation.
research Administration of Nrf-2-Modified Hair-Follicle MSCs Ameliorates DSS-Induced Ulcerative Colitis in Rats
Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.
research 4‐octyl itaconate alleviates cisplatin‐induced ferroptosis possibly via activating the NRF2 /HO ‐1 signalling pathway
4-octyl itaconate may prevent hearing loss caused by the drug cisplatin by activating certain cell protection pathways.
research Hair follicle transplantation promotes skin ulcer healing in a mouse model of experimental diabetes
Hair follicle transplantation speeds up wound healing in diabetic mice.
research Frontal fibrosing alopecia preceding the development of vitiligo: A case report
Hair loss condition FFA was seen before the appearance of skin depigmentation vitiligo in a patient.
research 097 LFA-1 blockade prevents the onset of alopecia areata in C3H/HeJ mice
Blocking LFA-1 prevents hair loss in mice.
research Co-editors’ Messages
Inflammation linked to the immune response may play a role in causing various types of hair loss.
research Abstract 18: Targeted epidermal ablation of EGFR causes local and systemic inflammation
Removing EGFR in skin causes inflammation and abnormal hair growth.
research Involvement of ILC1-like innate lymphocytes in human autoimmunity, lessons from alopecia areata
ILC1-like cells can independently cause alopecia areata.
research Possible role of β‐hydroxybutyrate in inducing inflammation in alopecia areata
High beta-hydroxybutyrate levels may worsen hair loss in alopecia areata.
research Scar Inhibition in Wound Healing: Mechanisms, Design, and Recent Advances
Advancements in gene therapy, stem cells, and biomaterials show promise for reducing scarring in wound healing, but face clinical challenges.
research The Role of Extracellular Vesicles in the Development and Treatment of Psoriasis: Narrative Review
Extracellular vesicles show promise for treating psoriasis by reducing inflammation and skin lesions.
research Editor's evaluation: Involvement of ILC1-like innate lymphocytes in human autoimmunity, lessons from alopecia areata
ILC1-like cells can independently cause alopecia areata by affecting hair follicles.
research Quantifying extracellular vesicle heterogeneity: the effect of process conditions on protein cargo for skin therapy
Standardized methods are needed to understand how process conditions affect extracellular vesicle protein content for skin therapy.
research Effects of Acanthus ebracteatus Vahl. extract and verbascoside on human dermal papilla and murine macrophage
Acanthus ebracteatus Vahl. extract and verbascoside may help prevent hair loss and promote hair growth due to their anti-inflammatory properties and ability to protect against cell death.
research Dermal lymphatic dilation in a mouse model of alopecia areata
Mice with alopecia areata had wider lymphatic vessels in their skin.