67 citations
,
July 2016 in “Reviews in Endocrine and Metabolic Disorders” Stress can worsen skin conditions by affecting hormone levels and immune response.
63 citations
,
October 2012 in “Wound Repair and Regeneration” Hair follicle grafting can help heal chronic leg ulcers.
46 citations
,
August 2006 in “Mechanisms of Development” Runx1 is crucial for proper hair structure and development.
40 citations
,
June 2009 in “Journal of Cutaneous Pathology” AGA patients have fewer hairs and smaller follicles; T:V ratio above 4:1 may indicate AGA.
38 citations
,
September 2017 in “Oncologist” Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.
38 citations
,
October 1988 in “Clinics in Dermatology” Minoxidil can help grow hair and make hair follicles bigger, but it can also cause side effects.
32 citations
,
June 2013 in “Journal of Investigative Dermatology” Mice without certain skin proteins had abnormal skin and hair development.
29 citations
,
March 2023 in “European Journal of Human Genetics” New genetic factors linked to acne risk were discovered, highlighting the role of certain pathways and genes.
24 citations
,
September 2002 in “Dermatologic Surgery” The study found that hair follicles are above muscle connections in the scalp, which may help protect stem cell areas.
23 citations
,
November 2011 in “Journal of the European Academy of Dermatology and Venereology” Hair loss is a rare but recognized symptom of pemphigus vulgaris, with patients usually regrowing hair after treatment.
20 citations
,
August 2014 in “Therapeutic delivery” The transfollicular route shows promise for noninvasive, targeted drug delivery but needs more research.
20 citations
,
September 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” MMP-9 is essential for proper hair canal formation.
16 citations
,
July 2013 in “The American Journal of Dermatopathology” Pigmented casts are common in several hair loss conditions and can help diagnose specific types of alopecia.
16 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.
14 citations
,
October 2018 in “PloS one” Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.
14 citations
,
September 2010 in “Annals of Plastic Surgery” Hair restoration has evolved from surgery to drugs to potential gene therapy, with improved results and ongoing research driven by high demand.
13 citations
,
December 2020 in “Dermatologic Therapy” Sebaceous glands in our skin, developing during pregnancy and active in puberty, produce sebum for skin lubrication, temperature control, and fighting germs, also help in hormone regulation, and their dysfunction can cause conditions like acne and hair loss.
10 citations
,
January 2010 in “Acta Histochemica Et Cytochemica” c-kit affects hair growth and color in alopecia areata and androgenetic alopecia.
9 citations
,
June 2017 in “Journal of Cutaneous Pathology” People with pemphigus vulgaris and pemphigus foliaceus often have smaller sebaceous glands on their scalp.
6 citations
,
January 2019 in “Journal of dermatology” Immune checkpoint inhibitors used in cancer therapy can cause hair loss, and understanding this can help manage the side effect.
4 citations
,
April 2024 in “The Journal of Cell Biology” Caspase-1 helps hair stem cells move to heal wounded or inflamed skin.
4 citations
,
May 2021 in “Biomedicines” Targeting the protein Caveolin-1 might help treat a type of scarring hair loss called Frontal Fibrosing Alopecia.
2 citations
,
June 2001 in “American Journal of Pathology” The document concludes that understanding how hair follicles naturally die and regenerate is important for insights into organ development and could impact health and disease treatment.
1 citations
,
February 2025 in “Scientific Reports” CD4 is crucial for maintaining skin stem cell balance and aiding wound healing.
1 citations
,
December 2023 Hair grows in cycles and changes with age, starting from fetal development.
1 citations
,
October 2018 in “InTech eBooks” The document concludes that treatments for cicatricial alopecia are not well-supported by evidence, but hair transplantation shows more predictable and satisfactory results.
1 citations
,
January 2018 in “Methods in molecular biology” The research found ways to activate melanocyte stem cells for potential treatment of skin depigmentation conditions.
1 citations
,
June 2012 in “Actas Dermo-Sifiliográficas” Early and aggressive treatment of scarring alopecia is important to prevent further hair follicle damage.
January 2026 in “Preprints.org” Nanotechnology shows promise for treating hair loss but faces safety and approval challenges.
November 2025 in “Journal of Skin and Sexually Transmitted Diseases” Trichofolliculoma was found in a person with amniotic band syndrome for the first time.