32 citations
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January 2017 in “Orphanet journal of rare diseases” FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
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January 1987 in “Dermatology” Minoxidil slows down skin cell growth and may help treat scars and skin conditions.
September 2016 in “European Journal of Pediatric Dermatology/PD. European journal of pediatric dermatology” Ulerythema ophryogenes causes hair thinning and inflammation, with limited treatment options.
September 2013 in “Helda (University of Helsinki)” Mutations in specific genes cause certain congenital defects in dogs, aiding in understanding similar human diseases.
68 citations
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January 2013 in “BMC Pharmacology and Toxicology” Glibenclamide slows breast cancer cell growth by stopping cell division.
38 citations
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May 2010 in “American Journal Of Pathology” 17β-Estradiol slows wound healing in male mice through estrogen receptor-α.
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January 2007 in “Biological & pharmaceutical bulletin” Glycine reduces skin pigmentation by lowering melanin production.
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February 2021 in “Scientific Reports” RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.
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December 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Nicotinamide applied to the scalp can slow down hair growth.
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September 2002 in “The Journal of clinical investigation/The journal of clinical investigation” Blocking testosterone speeds up wound healing in males.
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October 2020 in “Stem cell research & therapy” DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
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July 2017 in “Oncology Letters” Lacking cyclin D3 reduces skin cancer growth without affecting normal skin cell growth.
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January 1981 in “Elsevier eBooks” Melatonin stops melanin production after tyrosinase action, with cyclic GMP mimicking this effect.
Finasteride reduces DHT to treat prostate issues and hair loss.
November 2003 in “Journal of Investigative Dermatology” Topical Imiquimod may fight vascular tumors by affecting blood vessels or the immune system, low iron might be linked to some hair loss, removing the top skin layer helps vitamin C get in, genetic testing helps diagnose skin conditions, and too much iron could worsen skin inflammation.
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May 2021 in “Journal of endocrinological investigation” APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.
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July 2009 in “Pediatrics in Review” Early diagnosis and treatment of congenital adrenal hyperplasia are crucial to manage symptoms and prevent complications.
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April 2009 in “Pediatrics in review” Doctors need to recognize and treat metabolic disorders in children early to prevent serious health issues.
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April 2016 in “British Journal of Dermatology” Buschke-Ollendorff syndrome is a rare genetic disorder causing skin and bone changes, with some cases also showing ADHD or developmental delays.
January 2024 in “Clinical, cosmetic and investigational dermatology” A child with a rare vitamin D-resistant condition improved with treatment.
176 citations
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September 2006 in “Stem Cells” BMP signaling prevents hair growth by stopping stem cell activation.
82 citations
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May 2009 in “Development” EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
56 citations
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March 2003 in “Journal of Investigative Dermatology” 17β-estradiol can reduce inflammation in the skin.
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August 1993 in “PubMed” IL-1 alpha stops hair follicle growth and hair production.
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June 2011 in “Molecular Medicine” Progesterone significantly reduces neuroblastoma tumor growth without harming healthy cells.
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December 2018 in “International journal of environmental research and public health/International journal of environmental research and public health” EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.
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August 2020 in “Acta histochemica” All-trans-retinoic acid stops mink hair growth by affecting cell growth and causing cell death.
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October 2015 in “Experimental dermatology” Adenine helps delay aging in human hair follicle cells.
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January 1998 in “Science” A mutation in the human hairless gene causes alopecia universalis.
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January 1997 in “Endocrinology” Testosterone can slow hair growth in adult monkeys, but a blocker called RU 58841 can counteract this and potentially help hair regrow.