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5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.

Dutasteride is safe and effective for treating hair loss, but may decrease libido.

Two existing drugs may help treat COVID-19 by inhibiting a key viral protein.

Local hormonal treatment for vulvovaginal atrophy is likely safe for women with estrogen receptor-positive breast cancer on aromatase inhibitors.

Using 5 alpha reductase inhibitors may increase dementia risk in the first two years.

11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.

New hybrid compound found to effectively prevent hair loss.

A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.

Long-term use of dutasteride can cause permanent erectile dysfunction in rats.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

3-tetrazolo steroidal analogs can strongly inhibit the enzyme linked to hair loss.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Dutasteride may protect the brain in early Parkinson's disease.

Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.

A cancer drug called nilotinib might cause hair loss due to inflammation around hair follicles.

EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.

Finasteride reduces movement issues in Parkinson's disease rats.

5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.

Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.

Immune checkpoint inhibitors can cause skin issues but are linked to better cancer outcomes.

Finasteride helps protect brain in old male rats.

New compounds may help treat prostate issues without affecting androgen receptors.