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research miR-761-hepcidin/Gpx4 pathway contribute to unexplained liver dysfunction in polycystic ovary syndrome by regulating liver iron overload and ferroptosis

16 citations , January 2023 in “Gynecological Endocrinology”

Liver damage in PCOS is linked to iron overload and cell death due to the miR-761-hepcidin/GPX4 pathway.

research Interleukin-1β-Induced Inhibition of Hair Growth In Vitro Is Mediated by Cyclic AMP

33 citations , January 1997 in “Journal of Investigative Dermatology”

research SYNTHESIS OF INOSITOL IN MICE

43 citations , March 1942 in “The Journal of experimental medicine/The journal of experimental medicine”

Mice need pantothenic acid to make inositol.

research Promoting axonal regeneration through exosomes: An update of recent findings on exosomal PTEN and mTOR modifiers

14 citations , October 2018 in “Brain Research Bulletin”

Exosomes help nerve fibers grow by affecting specific cell signaling pathways.

research Lysophosphatidic acid increases the proliferation and migration of adipose-derived stem cells via the generation of reactive oxygen species

24 citations , July 2015 in “Molecular Medicine Reports”

Lysophosphatidic acid boosts stem cell growth and movement by creating reactive oxygen species.

research The role of Pygo2 during intestinal tumor initiation and progression in vivo

January 2016

Pygo2 is important for early growth and progression of intestinal tumors, and could be a target for treating cancers with certain mutations.

research Androgens Regulate Tau Phosphorylation Through Phosphatidylinositol 3-Kinase–Protein Kinase B–Glycogen Synthase Kinase 3β Signaling

14 citations , June 2022 in “Neuroscience”

research Lonicerin promotes wound healing in diabetic rats by enhancing blood vessel regeneration through Sirt1-mediated autophagy

40 citations , December 2023 in “Acta Pharmacologica Sinica”

research The Force Is Strong with This One: Metabolism (Over)powers Stem Cell Fate

33 citations , March 2018 in “Trends in cell biology”

Metabolism plays a key role in determining stem cell fate.

research Cyclooxygenases in the skin: pharmacological and toxicological implications

165 citations , September 2003 in “Toxicology and applied pharmacology”

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

research 879 Molecular network of Smads and Id2 genes in hair follicle stem cells regulation

April 2017 in “Journal of Investigative Dermatology”

The BMP/Smads pathway and Id2 gene control hair follicle stem cells, affecting their rest and growth phases.

research Intrinsic ROS Drive Hair Follicle Cycle Progression by Modulating DNA Damage and Repair and Subsequently Hair Follicle Apoptosis and Macrophage Polarization

20 citations , January 2022 in “Oxidative Medicine and Cellular Longevity”

Reactive oxygen species (ROS) influence hair growth by causing DNA damage, cell death, and changes in immune cells.

research Signaling pathways and targeted therapeutic strategies for polycystic ovary syndrome

October 2023 in “Frontiers in endocrinology”

Effective PCOS treatments require targeting specific signaling pathways.

research The AR/miR-221/IGF-1 pathway mediates the pathogenesis of androgenetic alopecia

2 citations , January 2023 in “International Journal of Biological Sciences”

A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.

research The role of hsa‐miR‐193a‐5p as an important factor for control of inositol in alopecia areata

June 2024 in “Skin Research and Technology”

hsa-miR-193a-5p may help diagnose and treat alopecia areata.

research LB1031 Immune Cell-Mediated Amplification of Stem Cell Activation in Hairy Melanocytic Nevus via Osteopontin-CD44 Axis

1 citations , July 2024 in “Journal of Investigative Dermatology”

Immune cells boost stem cell activity in hairy moles, causing more hair growth.

research OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes

6 citations , November 2022 in “Antioxidants”

OR2AT4 helps reduce aging and cell damage in human skin cells.

research Effects of the PI3K/Akt signaling pathway on the hair inductivity of human dermal papilla cells in hair beads

12 citations , April 2022 in “Journal of Bioscience and Bioengineering”

Activating the PI3K/Akt pathway improves hair growth by human dermal papilla cells in hair beads.

research Mitochondrial dysfunction in diabetic neuropathy may be involved in the development of neuropathic pain via a reduction in neurosteroid synthesis

4 citations , April 2017 in “F1000Research”

Mitochondrial problems in diabetic nerve damage might cause pain by lowering the production of certain nerve-related steroids.

research Small Molecule Inhibitors and Inflammatory Skin Diseases

March 2018 in “Suez Canal University Medical Journal”

New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.

research Studies of E2s Related to Unconventional Ubiquitination in Arabidopsis thaliana

December 2018

UBC13 and UBC22 enzymes are important for plant growth and development in Arabidopsis thaliana.

research Roles of Type 10 17beta-Hydroxysteroid Dehydrogenase in Intracrinology and Metabolism of Isoleucine and Fatty Acids

26 citations , March 2006 in “Endocrine, metabolic & immune disorders. Drug targets”

This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.

research ICP5249 Promotes Hair Growth by Activating the AMPK-Autophagy Signaling Pathway

5 citations , July 2024 in “Journal of Microbiology and Biotechnology”

ICP5249 helps hair grow by activating a specific cell pathway.

research Rps14 upregulation promotes inner ear progenitor proliferation and hair cell regeneration in the neonatal mouse cochlea

September 2022 in “Research Square (Research Square)”

Increasing Rps14 helps grow more inner ear cells and repair hearing cells in baby mice.

research OsPHR2 Is Involved in Phosphate-Starvation Signaling and Excessive Phosphate Accumulation in Shoots of Plants

546 citations , February 2008 in “PLANT PHYSIOLOGY”

OsPHR2 gene causes excessive phosphate in rice shoots, affecting plant growth and root development.

research Induction of Pluripotent Stem Cells Via Wnt Signaling Pathway.

January 2013 in “eScholarship (California Digital Library)”

Activating Wnt signaling improves the efficiency and safety of creating stem cells.

Graphene Oxide and Indole-3-Acetic Acid Cotreatment Regulates the Root Growth of Brassica Napus L. via Multiple Phytohormone Pathways

research Graphene oxide and indole-3-acetic acid cotreatment regulates the root growth of Brassica napus L. via multiple phytohormone pathways

34 citations , March 2020 in “BMC plant biology”

Graphene oxide and indole-3-acetic acid together inhibit root growth in Brassica napus L. by affecting multiple plant hormone pathways.

research Bioinformatics analysis and verification of m6A related genes based on the construction of keloid diagnostic model

January 2023 in “Research Square (Research Square)”

IGF2BP3 gene is up-regulated in keloid patients, suggesting potential targets for treatment.

research Urokinase plasminogen activator (uPA) is a positive regulator of outer root sheath keratinocyte proliferation

2 citations , July 2004 in “Cell Biology International”

uPA helps hair follicle cells grow.

research CD34 ⁺ cell–derived fibroblast-macrophage cross-talk drives limb ischemia recovery through the OSM-ANGPTL signaling axis

39 citations , April 2023 in “Science Advances”

CD34⁺ cells help heal damaged limbs by promoting blood vessel growth.

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