4 citations
,
December 2021 in “Clinical and Experimental Reproductive Medicine” Higher estrone-to-estradiol ratios are linked to worse glucose metabolism and insulin resistance in women with PCOS.
February 2022 in “Mediators of Inflammation” Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.
12 citations
,
May 2005 in “Fertility and Sterility” Higher insulin levels are linked to larger ovaries in women with idiopathic hirsutism.
16 citations
,
January 2012 in “European Journal of Endocrinology” The study suggests certain ACE gene variations are more common in women with PCOS and may be linked to increased insulin resistance.
22 citations
,
January 2012 in “Obstetrics and Gynecology International” Obese women with PCOS have more cardiovascular risk factors, and waist-to-stature ratio is a better health marker than waist-to-hip ratio.
3 citations
,
August 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” People with PCOS have higher levels of PAI-1, which may increase their risk of heart disease and fertility issues.
January 2014 in “Healthy aging research” Polycystic ovarian disease symptoms can continue after menopause, making diagnosis and management in older women challenging.
24 citations
,
August 2005 in “Health and Quality of Life Outcomes” Women with androgenetic alopecia experience worse physical well-being and quality of life, but similar mental health compared to those without it.
77 citations
,
March 2004 in “Human Reproduction” Women with irregular periods and/or excessive body hair are more likely to have polycystic ovaries, and this condition is linked to higher health risks.
2 citations
,
June 2024 in “Journal of the Pakistan Medical Association” Higher SFRP-4 levels were found in people without a diabetic family history.
January 2026 in “Journal of Clinical Medicine” Improving diet and lifestyle can help manage skin conditions linked to insulin resistance and inflammation.
15 citations
,
July 2012 in “Biological trace element research” Higher hair calcium to magnesium ratios and lower chromium levels in hair may indicate insulin resistance in Korean men.
3 citations
,
October 2010 in “Journal of Experimental & Clinical Medicine” Obesity is a major risk factor for insulin resistance in Taiwanese women with PCOS, which is also an independent risk factor for metabolic syndrome.
1 citations
,
January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” Hypothyroidism may worsen metabolic problems like insulin resistance and obesity in women with PCOS.
121 citations
,
April 2008 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Many women in southern China have polycystic ovary syndrome, with some symptoms differing from Western women.
8 citations
,
March 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.
1 citations
,
November 2017 in “International journal of clinical endocrinology and metabolism” The supplement with Myo-inositol and D-chiro-inositol improves metabolic symptoms in PCOS, especially when combined with metformin.
May 2022 in “The Journal of Clinical Pharmacology” Metformin reduces certain hormone levels in men with early-onset hair loss.
1 citations
,
November 2023 in “Journal of neurology” A patient with a nerve disorder died from infection complications after developing insulin resistance from a treatment.
January 2023 in “International journal of medical science and health research” Anovulatory PCOS patients are younger with longer cycles and higher blood pressure and hormone levels.
28 citations
,
October 2013 in “Journal of The American Academy of Dermatology” Ovarian SAHA syndrome makes women with PCOS more resistant to insulin and increases their risk of blood sugar problems.
53 citations
,
January 2011 in “Diabetes” People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.
February 2013 in “Journal of The American Academy of Dermatology” There is no significant link between insulin resistance and certain hair disorders like idiopathic hirsutism and androgenic alopecia.
15 citations
,
October 2011 in “Gynecological Endocrinology” Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.
6 citations
,
April 2016 in “Journal of the Formosan Medical Association” Metformin improved insulin resistance and BMI in overweight Taiwanese women with PCOS, and a 2-hour insulin test may be a good screening tool.
March 2012 in “Journal of Pediatric and Adolescent Gynecology” Teens with PCOS have a higher risk of type 2 diabetes and need regular glucose checks.
26 citations
,
June 2014 in “Fertility and Sterility” Teens with PCOS and a mom with PCOS have higher insulin resistance and lower adiponectin levels, which could signal early metabolic problems.
8 citations
,
November 2012 in “Journal of Endocrinological Investigation” Greek women with classic PCOS are more likely to have metabolic syndrome and insulin resistance than those with newer PCOS types.
February 2010 in “Journal of The American Academy of Dermatology” White hirsute women with PCOS have higher insulin resistance, but similar nitric oxide and fibrinogen levels compared to those with idiopathic hirsutism.
40 citations
,
April 2008 in “European journal of endocrinology” Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.